- ►nih.gov HJ Nam, MD Lane, E Padron, B Gurda, R … - Journal of Virology, 2007 - Am Soc Microbiol Adeno-associated viruses (AAVs) are being developed as gene therapy vectors, and
their efficacy could be improved by a detailed understanding of their viral
capsid structures. AAV serotype 8 (AAV8) shows a significantly greater ... Cited by 25 - Related articles - BL Direct - All 11 versions
JC Grieger, VW Choi, RJ Samulski - Nature Protocols, 2006 - nature.com The adeno-associated virus (AAV) is one of the most promising viral vectors for
human gene therapy. As with any potential therapeutic system, a thorough
understanding of it at the in vitro and in vivo levels is required. Over ... Cited by 21 - Related articles - BL Direct - All 3 versions
M Natkunarajah, P Trittibach, J McIntosh, Y … - Gene Therapy, 2007 - nature.com To date adeno-associated viral (AAV) vectors are the only gene therapy vectors
that have been shown to efficiently transduce photoreceptor cells and have thus
become the most commonly used vector for ocular transduction. Various AAV ... Cited by 19 - Related articles - BL Direct - All 3 versions
RD Wideman, ILY Yu, TD Webber, CB Verchere … - Proceedings of the National Academy of Sciences, 2006 - National Acad Sciences Glucagon-like peptide 1 (GLP-1) is a hormone that has received significant
attention as a therapy for diabetes because of its ability to stimulate insulin
biosynthesis and release and to promote growth and survival of ... Cited by 21 - Related articles - BL Direct - All 10 versions
LJ Lai, X Xiao, JH Wu - Journal of biomedical science, 2007 - Springer 1 Graduate Institute of Clinical Medical Sciences, College of Medicine, Chang
Gung University, Kwei San, Tao Yuan, 333, Taiwan; 2 Department of Ophthalmology,
Chang Gung Memorial Hospital, 199 Tung-Hwa North Road, Taipei, 105, Taiwan; ... Cited by 17 - Related articles - BL Direct - All 5 versions
- ►nih.gov I Kwon, DV Schaffer - Pharmaceutical research, 2008 - Springer Received July 4, 2007; accepted August 3, 2007; published online 1 September
2007 Abstract. Gene delivery vectors based on adeno-associated virus (AAV) are
highly promising due to several desirable features of this parent virus, ... Cited by 14 - Related articles - BL Direct - All 5 versions
L Pasquali, Y Fan, M Trucco, S Ringquist - Trends in Biotechnology, 2006 - Elsevier Type 1 Diabetes (T1D) is an autoimmune disease resulting from the destruction of
pancreatic insulin-producing β cells that most frequently occurs in genetically
predisposed children. Recent observations illustrating the regenerative ... Cited by 10 - Related articles - All 5 versions
H Cheng, SH Wolfe, V Valencia, K Qian, L … - Journal of Biomedical Science, 2007 - Springer 1 Department of Comparative Biomedical Sciences, School of Veterinary Medicine,
Louisiana State Univer- sity, Baton Rouge, LA, USA; 2 ChildrenÕs Research
Institute, Department of Pediatrics, University of South Florida, 140 7th ... Cited by 11 - Related articles - BL Direct - All 2 versions
A Casellas, A Salavert, J Agudo, E Ayuso, V … - Diabetes, 2006 - Am Diabetes Assoc Type 1 diabetic patients are diagnosed when β-cell destruction is almost
complete. Reversal of type 1 diabetes will require β-cell regeneration from
islet cell precursors and prevention of recurring autoimmunity. IGF-I ... Cited by 9 - Related articles - BL Direct - All 7 versions
AR Barbu, B Bodin, M Welsh, L Jansson, N … - Diabetologia, 2006 - Springer Abstract Aims/hypothesis Successful gene transfer to pancreatic islets might be
a powerful tool for dissecting the biological pathways involved in the
functional impairment and destruction of beta cells in type 1 diabetes. In ... Cited by 8 - Related articles - BL Direct - All 4 versions
