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Scholar Results 1 - 10 of about 34 citing Park: Accelerated diabetic nephropathy in mice lacking the Peroxisome Proliferator–Activated.... (0.12 sec) 

Regulation of renal fatty acid and cholesterol metabolism, inflammation, and fibrosis in …

- shouxi.net
G Proctor, T Jiang, M Iwahashi, Z Wang, J Li, … - Diabetes, 2006 - Am Diabetes Assoc
In Akita and OVE26 mice, two genetic models of type 1 diabetes, diabetic
nephropathy is characterized by mesangial expansion and loss of podocytes,
resulting in glomerulosclerosis and proteinuria, and is associated with ...
Cited by 29 - Related articles - BL Direct - All 5 versions

Obesity, insulin resistance, and renal function


SF Knight, JD Imig - Microcirculation, 2007 - informahealthcare.com
There is a growing body of evidence indicating that obesity and insulin
resistance contribute to the progression of renal disease. A low-grade
inflammatory response occurs in obesity and insulin resistance that causes ...
Cited by 20 - Related articles - BL Direct - All 4 versions

Combined use of rosiglitazone and fenofibrate in patients with type 2 diabetes: prevention of …

- diabetesjournals.org
G Boden, C Homko, M Mozzoli, M Zhang, K … - Diabetes, 2007 - Am Diabetes Assoc
Elevated plasma free fatty acid (FFA) levels are responsible for much of the
insulin resistance in obese patients with type 2 diabetes. To lower plasma FFA
levels effectively and long term, we have treated eight obese patients with ...
Cited by 19 - Related articles - BL Direct - All 11 versions

Fibrates and future PPARα agonists in the treatment of cardiovascular disease


B Staels, M Maes, A Zambon - Nature Clinical Practice Cardiovascular Medicine, 2008 - nature.com
B Staels is Professor of Pharmacy and Director of the Department of
Atherosclerosis, Institut Pasteur de Lille, UMR545 Inserm, Lille, France. His
research focuses on molecular pharmacology of cardiovascular and metabolic ...
Cited by 18 - Related articles - All 3 versions

Peroxisome Proliferator–Activated Receptor α/γ Dual Agonist Tesaglitazar Attenuates …


DR Cha, X Zhang, Y Zhang, J Wu, D Su, JY … - Diabetes, 2007 - Am Diabetes Assoc
Peroxisome proliferator–activated receptors (PPARs) are nuclear transcription
factors and play a central role in insulin sensitivity, lipid metabolism, and
inflammation. Both PPARα and -γ are expressed in the kidney, and their ...
Cited by 17 - Related articles - BL Direct - All 4 versions

Homocysteine induces mesangial cell apoptosis via activation of p38-mitogen-activated …


S Shastry, AJ Ingram, JW Scholey, LR James - Kidney international, 2006 - nature.com
Hyperhomocysteinemia is prevalent among patients with chronic kidney disease
(CKD) and has been linked to progressive kidney and vascular diseases. Increased
glomerular mesangial cell (MC) turnover, including proliferation and ...
Cited by 11 - Related articles - BL Direct - All 4 versions

PPARs and the kidney in metabolic syndrome

- physiology.org [PDF] 
X Ruan, F Zheng, Y Guan - American Journal of Physiology- Renal Physiology, 2008 - Am Physiological Soc
215 articles, 104 of which you can access free at: This article cites
http://ajprenal.physiology.org/cgi/content/full/294/5/F1032#BIBL ... 1 other
HighWire hosted article: This article has been cited by
Cited by 10 - Related articles - BL Direct - All 3 versions

PPAR-alpha agonist fenofibrate induces renal CYP enzymes and reduces blood pressure and …


X Zhao, LY Li - Am J Nephrol, 2008 - content.karger.com
We have previously shown that fenofibrate, a peroxisome proliferator-activated
receptor- activator, increases renal cytochrome P450 (CYP)-derived eicosanoids
and improves endothelial function in pre-diabetic obese rats. The present ...
Cited by 8 - Related articles - All 5 versions

Knocking Out Peroxisome Proliferator-Activated Receptor (PPAR) α Inhibits Radiation- …


W Zhao, S Iskandar, M Kooshki, JG Sharpe, … - Radiation research, 2007 - BioOne
Peroxisome proliferator-activated receptor (PPAR) α, a member of the
ligand-activated nuclear receptor superfamily, plays an important role in lipid
metabolism and glucose homeostasis and is highly expressed in the kidney. ...
Cited by 9 - Related articles - All 8 versions

Long-term treatment of glucagon-like peptide-1 analog exendin-4 ameliorates diabetic …

- asnjournals.org
CW Park, HW Kim, SH Ko, JH Lim, GR Ryu, … - Journal of the American Society of Nephrology, 2007 - Am Soc Nephrol
Glucagon-like peptide-1 (GLP-1) is a gut incretin hormone and is a new
clinically available class of agents for improving of insulin resistance in both
animals and humans with type 2 diabetes. These studies aimed to determine ...
Cited by 7 - Related articles - All 8 versions


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