G Wolf, FN Ziyadeh - Nephron Physiol, 2007 - content.karger.com One of the earliest clinically detectable abnormalities in diabetic nephropathy is microalbuminuria
that eventually progresses to proteinuria. The degree of proteinuria correlates with the progression
of glomerulosclerosis and tubulointerstitial fibrosis. In the glomerulus, a typical ... Cited by 41 - Related articles - BL Direct - All 5 versions
K Sharma, S RamachandraRao, G Qiu, … - The Journal of …, 2008 - pubmedcentral.nih.gov 1 Translational Research in Kidney Disease, Division of Nephrology, Department of
Medicine, University of California, San Diego, La Jolla, California, USA. 2 Veterans Administration
San Diego Healthcare System, La Jolla, California, USA. 3 Center for Novel Therapies in ... Cited by 40 - Related articles - BL Direct - All 8 versions
JJ Li, SJ Kwak, DS Jung, JJ Kim, TH Yoo, DR Ryu, SH … - Kidney International, 2007 - nature.com Glomerular visceral epithelial cells, namely podocytes, are highly specialized cells and give
rise to primary processes, secondary processes, and finally foot processes. The foot processes
of neighboring podocytes interdigitate, leaving between them filtration slits. These are ... Cited by 16 - Related articles - BL Direct - All 3 versions
D Landau - Current opinion in nephrology and hypertension, 2006 - pdfs.journals.lww.com Purpose of review Tight junctions are intercellular seams sealing and preventing the entrance
of microorganisms or unwanted substances from the luminal compartment. They also define
the border between the basolateral and apical membranes of polarized cells, thus ... Cited by 13 - Related articles - BL Direct - All 6 versions
- ►problemsinanes.com GR Reddy, K Kotlyarevska, RF Ransom, RK … - Current Opinion in …, 2008 - journals.lww.com Introduction Diabetes mellitus accounts for approximately one-third of all new cases of end stage
renal disease (ESRD) worldwide, and is the most common cause of ESRD in the United States
where approximately 45% of new cases of ESRD are secondary to diabetes mellitus [1]. ... Cited by 13 - Related articles - BL Direct - All 9 versions
S Nakamuta, H Endo, Y Higashi, A … - Journal of …, 2008 - informahealthcare.com The infiltration of human immunodeficiency virus (HIV)-1, such as by HIV-infected
leukocytes, across an injured blood-brain barrier (BBB) is a characteristic pathologic manifestation
of HIV-1–associated dementia. HIV-1 gp120 has been implicated as a cause of ... Cited by 4 - Related articles - All 4 versions
MC Wagner, G Rhodes, E Wang, V Pruthi, E Arif, … - Journal of Biological …, 2008 - ASBMB Glomerular injury is often characterized by the effacement of podocytes, loss of slit
diaphragms, and proteinuria. Renal ischemia or the loss of blood flow to the kidneys has been
widely associated with tubular and endothelial injury but rarely has been shown to induce ... Cited by 2 - Related articles - All 3 versions
JM Teiken, JL Audettey, DI Laturnus, S Zheng, … - … Record Part B: The … - interscience.wiley.com Recent studies show that podocyte nuclear density (N V ) and numbers of renal podocytes per
glomerulus (N) are altered in experimental and spontaneous diabetes mellitus. N V and N are
generally reduced, and it has been hypothesized that these morphological changes may ... Cited by 2 - Related articles - BL Direct - All 2 versions
M Kimura, M Toyoda, M Kato, K Kobayashi, M Abe, T … - Internal Medicine, 2008 - J-STAGE Background Alpha-actinin-4 is an actin filament crosslinking protein that interacts with intercellular
adhe- sion molecules. Recent animal studies suggested that alpha-actinin-4 is an essential component
of the glomerular filtration barrier. However, little is known about its expression in human ... Cited by 1 - Related articles - All 2 versions
