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Biochemistry and physiology of mammalian secreted phospholipases A2

- washington.edu [PDF] 
G Lambeau, MH Gelb, 2008 - Annual Reviews
Phospholipases A 2 (PLA2s) are esterases that hydrolyze the sn-2 ester of
glycerophospholipids and constitute one of the largest families of lipid
hydrolyzing enzymes. The mammalian genome contains 10 enzymatically active ...
Cited by 33 - Related articles - All 4 versions

Transgenic expression of group V, but not group X, secreted phospholipase A2 in mice leads …

- jbc.org
M Ohtsuki, Y Taketomi, S Arata, S Masuda, Y … - Journal of Biological Chemistry, 2006 - ASBMB
In an effort to elucidate the functions of secreted phospholipase A 2 (sPLA 2 )
enzymes in vivo, we generated transgenic (Tg) mice for group V sPLA 2 (sPLA 2
-V) and group X sPLA 2 (sPLA 2 -X), which act potently on ...
Cited by 17 - Related articles - All 7 versions

[PDF] Recombinant production and properties of binding of the full set of mouse secreted …


M Rouault, C Le Calvez, E Boilard, F Surrel, … - Biochemistry, 2007 - faculty.washington.edu
ABSTRACT: To date, 12 secreted phospholipases A2 (sPLA2s) have been identified
in the mouse species and divided into three structural collections (I/II/V/X,
III, and XII). On the basis of their different molecular properties and ...
Cited by 15 - Related articles - View as HTML - All 5 versions

Human group III secreted phospholipase A2 promotes neuronal outgrowth and survival.


S Masuda, K Yamamoto, T Hirabayashi, Y … - The Biochemical journal, 2008 - ncbi.nlm.nih.gov
Human sPLA2-III [group III secreted PLA2 (phospholipase A2)] is an atypical
sPLA2 isoenzyme that consists of a central group III sPLA2 domain flanked by
unique N- and C-terminal domains. In the present study, we found that ...
Cited by 10 - Related articles - BL Direct - All 5 versions

Analyses of group III secreted phospholipase A2 transgenic mice reveal potential …


H Sato, R Kato, Y Isogai, G Saka, M Ohtsuki, … - Journal of Biological Chemistry, 2008 - ASBMB
Among the many mammalian secreted phospholipase A 2 (sPLA 2 ) enzymes, PLA2G3
(group III secreted phospholipase A 2 ) is unique in that it possesses unusual
N- and C-terminal domains and in that its central sPLA 2 domain is ...
Cited by 10 - Related articles - All 3 versions

Biology of Secretory Phospholipase A 2


BB Boyanovsky, NR Webb - Cardiovascular Drugs and Therapy, 2009 - Springer
Page 1. REVIEW Biology of Secretory Phospholipase A 2 Boris B. Boyanovsky
& Nancy R. Webb Published online: 14 October 2008 # Springer ...
Cited by 8 - Related articles - All 3 versions

Important genetic checkpoints for insulin resistance in salt-sensitive(S) Dahl rats


MF Shehata - Cardiovascular diabetology, 2008 - cardiab.com
Despite the marked advances in research on insulin resistance (IR) in humans and
animal models of insulin resistance, the mechanisms underlying high salt-induced
insulin resistance remain unclear. Insulin resistance is a multifactorial ...
Cited by 5 - Related articles - Cached - All 8 versions

Glucose homeostasis, insulin secretion, and islet phospholipids in mice that overexpress …

- physiology.org
S Bao, DA Jacobson, M Wohltmann, A Bohrer, … - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc
Studies with genetically modified insulinoma cells suggest that group VIA
phospholipase A 2 (iPLA 2 β) participates in amplifying glucose-induced insulin
secretion. INS-1 insulinoma cells that overexpress iPLA 2 β, for example, ...
Cited by 5 - Related articles - BL Direct - All 5 versions

An emerging risk factor for obesity: does disequilibrium of polyunsaturated fatty acid …


G Ailhaud, P Guesnet, SC Cunnane - British Journal of Nutrition, 2008 - Cambridge Univ Press
1 ISDBC, Université de Nice Sophia-Antipolis, CNRS, 28 avenue Valrose, Nice
06100, France 2 Nu.Re.Li.Ce, INRA, UR909, Jouy-en-Josas cedex 78352, France 3
Research Center on Aging, Université de Sherbrooke, 1036 Belvedere Street ...
Cited by 4 - Related articles - All 5 versions

Structural basis for bile salt inhibition of pancreatic phospholipase A2

- nih.gov
YH Pan, BJ Bahnson - Journal of molecular biology, 2007 - Elsevier
Bile salt interactions with phospholipid monolayers of fat emulsions are known
to regulate the actions of gastrointestinal lipolytic enzymes in order to
control the uptake of dietary fat. Specifically, on the lipid/aqueous ...
Cited by 3 - Related articles - All 6 versions


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