- ►nih.gov M Claret, MA Smith, RL Batterham, C … - Journal of Clinical …, 2007 - Am Soc Clin Investig 1 Centre for Diabetes and Endocrinology, Rayne Institute, University College London,
London, United Kingdom. 2 Neurosciences Institute, Pathology and Neuroscience Division, Ninewells
Hospital and Medical School, University of Dundee, Dundee, United Kingdom. 3 Cellular ... Cited by 64 - Related articles - BL Direct - All 15 versions
N Marty, M Dallaporta, B Thorens - Physiology (Bethesda, Md.), 2007 - ncbi.nlm.nih.gov Neuronal circuits in the central nervous system play a critical role in orchestrating the control
of glucose and energy homeostasis. Glucose, beside being a nutrient, is also a signal detected
by several glucose-sensing units that are located at different anatomical sites and ... Cited by 22 - Related articles - BL Direct - All 4 versions
- ►pnas.org MJ Wolfgang, SH Cha, A Sidhaye, S … - Proceedings of the …, 2007 - National Acad Sciences Hypothalamic malonyl-CoA has been shown to function in global energy homeostasis by modulating
food intake and energy expenditure. Little is known, however, about the regulation of
malonyl-CoA concentration in the central nervous system. To address this issue we ... Cited by 18 - Related articles - BL Direct - All 9 versions
FQ Zhao, AF Keating - Current Genomics, 2007 - pubmedcentral.nih.gov Glucose is the major energy source for mammalian cells as well as an important substrate for
protein and lipid synthesis. Mammalian cells take up glucose from extracellular fluid into the
cell through two families of structurallyrelated glucose transporters. The facilitative ... Cited by 12 - Related articles - BL Direct - All 5 versions
- ►endojournals.org X Yang, J Mastaitis, T Mizuno, CV Mobbs - Endocrinology, 2007 - Endocrine Soc Because appetite, hypothalamic gene expression, reproductive function, and adrenal function
are highly sensitive to acute changes in plasma glucose levels, it has been hypothesized hypothalamic
neurons sensitive to glucose play a role in regulating these functions. To assess this ... Cited by 11 - Related articles - BL Direct - All 3 versions
MS Freiberg, MJ Pencina, RB D'Agostino, K Lanier, … - Obesity, 2008 - depts.washington.edu IntroductIon Obesity has reached epidemic proportions internationally (1,2). Excess adiposity
augments the risk for a variety of vas- cular and nonvascular diseases, and leads to considerable
health care expenditure (3,4). Consequently, the prevention, identification, and treatment ... Cited by 10 - Related articles - View as HTML - All 3 versions
- ►physiology.org IA Simpson, D Dwyer, D Malide, KH Moley … - American Journal of …, 2008 - Am Physiological Soc Glucose metabolism is vital to most mammalian cells, and the passage of glucose across cell
membranes is facilitated by a family of integral membrane transporter proteins, the GLUTs. There
are currently 14 members of the SLC2 family of GLUTs, several of which have been the ... Cited by 9 - Related articles - All 4 versions
N Marty, I Bady, B Thorens - Diabetes, 2006 - Am Diabetes Assoc The pancreatic β-cell paradigm for glucose sensing has been proposed to apply to brain glucose
sensors controlling counterregulation to hypoglycemia and feeding behavior. Over recent
years, we tested this model in mice by first showing that inactivation of the GLUT2 gene ... Cited by 8 - Related articles - BL Direct - All 4 versions
- ►physiology.org KM Eny, T Wolever, B Fontaine-Bisson, A … - Physiological …, 2008 - Am Physiological Soc Glucose sensing in the brain has been proposed to be involved in regulating food intake, but
the mechanism is not known. Glucose transporter type 2 (GLUT2)-null mice fail to control their
food intake in response to glucose, suggesting a potential role for this transporter as a ... Cited by 6 - Related articles - All 3 versions
N Horike, H Sakoda, A Kushiyama, H Ono, M … - Journal of Biological …, 2008 - ASBMB AMP-activated protein kinase (AMPK) activation reportedly suppresses transcriptional activity
of the cAMP-responsive element (CRE) in the phosphoenolpyruvate carboxykinase C
(PEPCK-C) promoter and reduces hepatic PEPCK-C expression. Although a previous ... Cited by 6 - Related articles - All 3 versions
