JS Kooner, JC Chambers, CA Aguilar-Salinas, DA … - Nature genetics, 2008 - nature.com We tested over 267,000 SNPs in 1,005 Northern Europeans and 248,000 in 1,006 Indian Asians for
association with triglycerides and HDL cholesterol, with replication in 10,536 subjects. We found
association of a nonsynonymous SNP ( ... Cited by 72 - Related articles - BL Direct - All 3 versions
… Denechaud, P Bossard, JMA Lobaccaro, L … - The Journal of …, 2008 - pubmedcentral.nih.gov The transcription factor carbohydrate-responsive element–binding protein (ChREBP) has emerged as a
central regulator of lipid synthesis in liver because it is required for glucose-induced expression
of the glycolytic enzyme liver– ... Cited by 32 - Related articles - BL Direct - All 6 versions
PD Denechaud, R Dentin, J Girard, C Postic - FEBS letters, 2008 - Elsevier Non-alcoholic fatty liver disease is tightly associated with insulin resistance, type 2 diabetes and
obesity, but the molecular links between hepatic fat accumulation and insulin resistance are not
fully identified. Excessive ... Cited by 19 - Related articles - All 9 versions
E Peschke, I Stumpf, I Bazwinsky, L Litvak, H … - Journal of pineal …, 2007 - edulife.com.br Inconsistent data have been reported concerning the influence of melatonin on the secretion of
insulin, on blood glucose, as well as on carbohydrate metabolism. Our previous investigations
demonstrated that melatonin inhib- ... Cited by 18 - Related articles - View as HTML - BL Direct - All 5 versions
- ►jlr.org G da Silva Xavier, GA Rutter, F Diraison, C … - The Journal of Lipid …, 2006 - ASBMB Pancreatic ß-cell dysfunction is central to the pathogenesis of type 2 diabetes and may involve
secretory failure through glucolipotoxity. The relative importance of the transcription factors
carbohydrate-responsive element ... Cited by 20 - Related articles - BL Direct - All 3 versions
MN Davies, BL O'Callaghan, HC Towle - Journal of Biological Chemistry, 2008 - ASBMB Carbohydrate response element-binding protein (ChREBP) is a glucose-responsive transcription factor
that activates genes involved in de novo lipogenesis in mammals. The current model for glucose
activation of ChREBP proposes that ... Cited by 11 - Related articles - All 5 versions
- ►physiology.org J Jason Collier, P Zhang, KB Pedersen, … - American Journal of …, 2007 - Am Physiological Soc Increased glucose flux generates metabolic signals that control transcriptional programs through
poorly understood mechanisms. Previously, we demonstrated a necessity in hepatocytes for c-Myc in
the regulation of a prototypical ... Cited by 8 - Related articles - BL Direct - All 9 versions
G Musso, R Gambino, M Cassader - Progress in Lipid Research, 2009 - Elsevier Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in Western
countries and is considered the hepatic manifestation of metabolic syndrome. The hallmark of NAFLD
is hepatic neutral lipid ... Cited by 7 - Related articles - All 2 versions
- ►pnas.org CA Stoltzman, CW Peterson, KT Breen, … - Proceedings of the …, 2008 - National Acad Sciences Glucose is a fundamental metabolite, yet how cells sense and respond to changes in extracellular
glucose concentration is not completely understood. We recently reported that the MondoA:Mlx dimeric
transcription factor directly ... Cited by 7 - Related articles - BL Direct - All 6 versions
K Iizuka, Y Horikawa - Biochemical and Biophysical Research …, 2008 - Elsevier BHLHB2/DEC1 is a transcription factor implicated in cell proliferation, apoptosis, and metabolism,
and is also known to play an important role in the regulation of the mammalian circadian rhythm.
However, its precise role in ... Cited by 5 - Related articles - All 3 versions
