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Scholar Results 1 - 10 of about 44 citing Schoenborn: The ATGL gene is associated with free fatty acids, triglycerides, and type 2 diabetes. (0.12 sec) 

Comparative studies of the role of hormone-sensitive lipase and adipose …

- physiology.org
M Ryden, J Jocken, V van Harmelen, A … - American Journal of …, 2007 - Am Physiological Soc
Hormone-sensitive lipase (HSL) and adipose triglyceride lipase (ATGL) regulate adipocyte lipolysis
in rodents. The purpose of this study was to compare the roles of these lipases for lipolysis in
human adipocytes. Subcutaneous adipose tissue was investigated. HSL and ATGL ...
Cited by 32 - Related articles - BL Direct - All 5 versions

Importance of TNFα and neutral lipases in human adipose tissue lipolysis

- cell.com
D Langin, P Arner - Trends in Endocrinology & Metabolism, 2006 - Elsevier
Catecholamines and natriuretic peptides stimulate human adipocyte lipolysis through an increase
in cAMP and cGMP levels, resulting in phosphorylation and activation of hormone-sensitive
lipase. A defect in hormone-sensitive lipase expression might contribute to the resistance ...
Cited by 30 - Related articles - All 7 versions

Adipose triglyceride lipase and hormone-sensitive lipase protein expression is …

- endojournals.org
JWE Jocken, D Langin, E Smit, WHM Saris, C … - Journal of Clinical …, 2007 - Endocrine Soc
Results: Fasting insulin levels and the degree of insulin resistance (using the homeostasis model
assessment index for insulin resistance) were negatively correlated with ATGL and HSL protein
expression, independent of age, gender, fat cell size, and body composition. Both mRNA ...
Cited by 28 - Related articles - BL Direct - All 8 versions

Adipocyte triglyceride lipase expression in human obesity

- physiology.org
GR Steinberg, BE Kemp, MJ Watt - American Journal of …, 2007 - Am Physiological Soc
We have investigated the gene and protein expression of adipose triglyceride lipase (ATGL)
and triglyceride (TG) lipase activity from subcutaneous and visceral adipose tissue of lean and
obese subjects. Visceral and subcutaneous adipose tissue was obtained from 16 age- ...
Cited by 24 - Related articles - BL Direct - All 4 versions

The role of neutral lipases in human adipose tissue lipolysis

- nursing2008.com
P Arner, D Langin - Current opinion in lipidology, 2007 - journals.lww.com
Recent findings: Until recently, only hormone sensitive lipase was considered important for the
regulation of lipolysis within fat cells. Recent rodent studies have suggested that adipose triglyceride
lipase may, however, be more important. The few human adipose triglyceride lipase ...
Cited by 21 - Related articles - BL Direct - All 6 versions

Dual lipolytic control of body fat storage and mobilization in Drosophila


S Gronke, G Muller, J Hirsch, S Fellert, A Andreou, … - PLoS Biol, 2007 - biology.plosjournals.org
Energy homeostasis is a fundamental property of animal life, providing a genetically fixed balance
between fat storage and mobilization. The importance of body fat regulation is emphasized by
dysfunctions resulting in obesity and lipodystrophy in humans. Packaging of storage fat in ...
Cited by 22 - Related articles - Cached - All 8 versions

Adipose triglyceride lipase and the lipolytic catabolism of cellular fat stores


R Zechner, PC Kienesberger, G Haemmerle, R … - The Journal of Lipid …, 2009 - ASBMB
Fatty acids (FAs) are essential components of all lipid classes and pivotal substrates for energy
production in all vertebrates. Additionally, they act directly or indirectly as signaling molecules
and, when bonded to amino acid side chains of peptides, anchor proteins in biological ...
Cited by 19 - Related articles - All 6 versions

Obesity and polymorphisms in genes regulating human adipose tissue


I Dahlman, P Arner - International Journal of Obesity, 2007 - nature.com
Obesity is the result of an imbalance between food intake and energy expenditure resulting in
the storing of energy as fat. Adipose tissue contains the largest store of energy in the body and
plays important roles in regulating energy partitioning. Developments in genomics, in ...
Cited by 19 - Related articles - BL Direct - All 3 versions

Catecholamine-induced lipolysis in adipose tissue and skeletal muscle in obesity


JWE Jocken, EE Blaak - Physiology & Behavior, 2008 - Elsevier
Increased fat storage in adipose and non-adipose tissue (eg skeletal muscle) characterizes the
obese insulin resistant state. Disturbances in pathways of lipolysis may play a role in the development
and maintenance of these increased fat stores. A reduced catecholamine-induced ...
Cited by 15 - Related articles - All 2 versions

Anti-angiogenic pigment epithelium-derived factor regulates hepatocyte …


C Chung, JA Doll, AK Gattu, C Shugrue, M Cornwell, P … - Journal of Hepatology, 2007 - Elsevier
Anti-angiogenic pigment epithelium-derived factor (PEDF) is a 50 kDa secreted glycoprotein
that is highly expressed in hepatocytes. Adipose triglyceride lipase (ATGL), a novel lipase critical
for triglyceride metabolism, is a receptor for PEDF. We postulated that hepatocyte ...
Cited by 13 - Related articles - All 12 versions


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