N Turner, CR Bruce, SM Beale, KL Hoehn, T … - Diabetes, 2007 - Am Diabetes Assoc A reduced capacity for mitochondrial fatty acid oxidation in skeletal muscle has
been proposed as a major factor leading to the accumulation of intramuscular
lipids and their subsequent deleterious effects on insulin action. Here, we ... Cited by 63 - Related articles - BL Direct - All 5 versions
- ►cell.com H Sano, L Eguez, MN Teruel, M Fukuda, TD … - Cell Metabolism, 2007 - Elsevier GLUT4 trafficking to the plasma membrane of muscle and fat cells is regulated by
insulin. An important component of insulin-regulated GLUT4 distribution is the
Akt substrate AS160 rab GTPase-activating protein. Here we show that Rab10 ... Cited by 44 - Related articles - All 7 versions
- ►nih.gov RV Farese, MP Sajan, H Yang, P Li, S … - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig 1 James A. Haley Veterans Medical Center, Tampa, Florida, USA. 2 Roskamp
Institute, Sarasota, Florida, USA. 3 Department of Internal Medicine and
Department of Molecular Medicine, University of South Florida College of ... Cited by 34 - Related articles - BL Direct - All 8 versions
EB Taylor, D An, HF Kramer, H Yu, NL Fujii, … - Journal of Biological Chemistry, 2008 - ASBMB The Akt substrate of 160 kDa (AS160) is phosphorylated on Akt substrate (PAS)
motifs in response to insulin and contraction in skeletal muscle, regulating
glucose uptake. Here we discovered a dissociation between AS160 protein ... Cited by 34 - Related articles - All 6 versions
- ►physiology.org JT Treebak, JB Birk, AJ Rose, B Kiens, EA … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc We investigated time- and intensity-dependent effects of exercise on
phosphorylation of Akt substrate of 160 kDa (AS160) in human skeletal muscle.
Subjects performed cycle exercise for 90 min (67% O 2 peak , n = 8), 20 min ... Cited by 26 - Related articles - BL Direct - All 4 versions
K Højlund, D Glintborg, NR Andersen, JB Birk … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— Impaired insulin-mediated total (R d ) oxidative and nonoxidative
glucose disposal (NOGD) was paralleled by reduced insulin-stimulated Akt
phosphorylation at Ser473 and Thr308 and AS160 phosphorylation in muscle of ... Cited by 17 - Related articles - BL Direct - All 3 versions
FQ Zhao, AF Keating - Current Genomics, 2007 - pubmedcentral.nih.gov Glucose is the major energy source for mammalian cells as well as an important
substrate for protein and lipid synthesis. Mammalian cells take up glucose from
extracellular fluid into the cell through two families of ... Cited by 12 - Related articles - BL Direct - All 5 versions
- ►jbc.org L Jiang, J Fan, L Bai, Y Wang, Y Chen, L … - Journal of Biological Chemistry, 2008 - ASBMB Insulin-stimulated GLUT4 translocation to the plasma membrane constitutes a key
process for blood glucose control. However, convenient and robust assays to
monitor this dynamic process in real time are lacking, which hinders ... Cited by 11 - Related articles - All 4 versions
- ►diabetesjournals.org [PDF] AO Chavez, JC Lopez-Alvarenga, ME Tejero, C … - Diabetes, 2008 - Am Diabetes Assoc Page 1. Physiologic and Molecular Determinants of Insulin Action In the
Baboon Alberto O. Chavez MD 1 , Juan C. Lopez-Alvarenga MD ... Cited by 8 - Related articles - BL Direct - All 4 versions
- ►jbc.org I Pagel-Langenickel, J Bao, JJ Joseph, DR … - Journal of Biological Chemistry, 2008 - ASBMB The pathophysiology underlying mitochondrial dysfunction in insulin-resistant
skeletal muscle is incompletely characterized. To further delineate this we
investigated the interaction between insulin signaling, mitochondrial ... Cited by 9 - Related articles - All 5 versions
