IA Leclercq, A Da Silva Morais, B Schroyen, N … - Journal of hepatology, 2007 - Elsevier Very few studies have addressed insulin resistance in sinusoidal liver cells.
These cells are not simply bystanders and passive witnesses of the changes
affecting the hepatocytes. They are target cells that will respond to the ... Cited by 40 - Related articles - All 6 versions
A Negre-Salvayre, C Coatrieux, C Ingueneau, … - British Journal of Pharmacology, 2008 - pubmedcentral.nih.gov Reactive carbonyl compounds (RCCs) formed during lipid peroxidation and sugar
glycoxidation, namely Advanced lipid peroxidation end products (ALEs) and
Advanced Glycation end products (AGEs), accumulate with ageing and ... Cited by 30 - Related articles - BL Direct - All 5 versions
S Vasdev, V Gill, P Singal - Cell Biochemistry and Biophysics, 2007 - Springer Abstract The vascular diseases, hypertension and ath- erosclerosis, affect
millions of individuals worldwide, and account for a large number of deaths
globally. A better understanding of the mechanism of these conditions will ... Cited by 21 - Related articles - BL Direct - All 3 versions
- ►fasebj.org AV Cantero, M Portero-Otin, V Ayala, N Auge … - The FASEB Journal, 2007 - FASEB Purpose: Low molecular weight carbonyl compounds, such as the -ketoaldehydes
methylglyoxal (MGO) and glyoxal (GO), are formed under hyperglycemic conditions
and behave as advanced glycation end product (AGE) precursors. They form ... Cited by 15 - Related articles - BL Direct - All 3 versions
PJ Thornalley - Drug metabolism and drug interactions, 2008 - pubmedcentral.nih.gov Glycation of proteins, nucleotides and basic phospholipids by glyoxal and
methylglyoxal – physiological substrates of glyoxalase 1 - is potentially
damaging to the proteome, genome and lipidome. Glyoxalase 1 suppresses ... Cited by 11 - Related articles - BL Direct - All 5 versions
AR Hipkiss - Biogerontology, 2007 - Springer Abstract The possibility is discussed that dietary restriction modulates ageing
and onset of related pathologies by, in addition to upregulation of pro-
teolysis, suppression of glycolysis which in turn decreases generation of ... Cited by 7 - Related articles - BL Direct - All 5 versions
X Jia, L Wu - Molecular and Cellular Biochemistry, 2007 - Springer Abstract Increased accumulation of methylglyoxal (MG) has been linked to
different insulin resistance states including diabetes and hypertension. In this
study, the ef- fects of MG on insulin signaling pathway were investi- ... Cited by 7 - Related articles - BL Direct - All 4 versions
T Gawlowski, B Stratmann, AO Stirban, M … - Thrombosis Research, 2007 - Elsevier Exposure of PBMCs to AGE-BSA and MG resulted in a dose- and time-dependent
increase of TF-expression by monocytes. AGE-BSA and MG induced enhanced
platelet-neutrophil aggregation. Examination of platelet activation showed ... Cited by 4 - Related articles - All 7 versions
HK Lee, I Seo, DJ Suh, HJ Lee, HT Park - Journal of Neurochemistry, 2009 - ingentaconnect.com Methylglyoxal (MGO) is an endogenous dicarbonyl compound that is highly produced
in hyperglycemic conditions. It forms advanced glycation endproducts that are
believed to contribute, as etiological factors, to the pathophysiology of ... Cited by 2 - Related articles - All 2 versions
