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Scholar Results 1 - 10 of about 20 citing Shinohara: Phosphatidylinositol 3-Kinase–Dependent Activation of Akt, an Essential Signal.... (0.09 sec) 

Apelin, an APJ receptor ligand, regulates body adiposity and favors the messenger …

- endojournals.org
K Higuchi, T Masaki, K Gotoh, S Chiba, I … - Endocrinology, 2007 - Endocrine Soc
Apelin, the endogenous ligand of the APJ receptor, has been identified in a
variety of tissues, including stomach, heart, skeletal muscle, and white adipose
tissue. We sought to clarify the effects of apelin on body adiposity and ...
Cited by 23 - Related articles - BL Direct - All 4 versions

Hemichannels in cardiomyocytes open transiently during ischemia and contribute to …

- physiology.org
K Shintani-Ishida, K Uemura, K Yoshida - American Journal of Physiology- Heart and Circulatory …, 2007 - Am Physiological Soc
The aim of this study was to investigate changes in hemichannel activity during
in vitro simulated ischemia [oxygen-glucose deprivation (OGD)] and the
contribution of hemichannels to ischemia-reperfusion injury in rat neonatal ...
Cited by 18 - Related articles - BL Direct - All 4 versions

Mitochondria are targets for geranylgeranylacetone-induced cardioprotection against …

- physiology.org
T Shinohara, N Takahashi, H Kohno, K … - American Journal of Physiology- Heart and Circulatory …, 2007 - Am Physiological Soc
It has been shown that orally administered geranylgeranylacetone (GGA), an
anti-ulcer drug, induces expression of heat shock protein 72 (HSP72) and
provides protection against ischemia-reperfusion in rat hearts. The ...
Cited by 13 - Related articles - BL Direct - All 3 versions

Pioglitazone but not glibenclamide improves cardiac expression of heat shock protein 72 and …

- shouxi.net
Y Taniguchi, T Ooie, N Takahashi, T … - Diabetes, 2006 - Am Diabetes Assoc
We tested the hypothesis that pioglitazone could restore expression of heat
shock protein (HSP)72 in insulin-resistant rat heart. At 12 weeks of age, male
Otsuka Long-Evans Tokushima Fatty (OLETF) rats and control (LETO) rats were ...
Cited by 7 - Related articles - BL Direct - All 5 versions

Insulin signaling, GSK-3, heat shock proteins and the natural history of type 2 diabetes …

- hspsanddiabetes.com [PDF] 
PL Hooper - Metabolic syndrome and related disorders, 2007 - liebertonline.com
Metabolic syndrome and type 2 diabetes are progressive, indolent, multi-organ
diseases. Un- derstanding the abnormalities of heat shock proteins (HSPs) in
these diseases is paramount to understanding their pathogenesis. In insulin ...
Cited by 7 - Related articles - BL Direct - All 5 versions

Receptor-mediated suppression of cardiac heat-shock protein 72 expression by testosterone …

- endojournals.org
H Kohno, N Takahashi, T Shinohara, T Ooie, … - Endocrinology, 2007 - Endocrine Soc
The impact of testosterone on cardiac expression of heat-shock protein 72
(HSP72) remains to be elucidated. Male Sprague Dawley rats 10 wk of age (adult)
were castrated. Four weeks later, testosterone (10 mg/kg, ip) was ...
Cited by 7 - Related articles - BL Direct - All 4 versions

Altered heat stress response following streptozotocin-induced diabetes


E Najemnikova, CD Rodgers, M Locke - Cell stress & chaperones, 2007 - pubmedcentral.nih.gov
The heat shock response involves activation of heat shock transcription factor 1
(Hsf1) followed by the rapid synthesis of the protective heat shock proteins
(Hsps). To determine if the stress experienced during streptozotocin (STZ)- ...
Cited by 6 - Related articles - BL Direct - All 10 versions

Hyperthermia treatment prevents angiotensin II-mediated atrial fibrosis and fibrillation via …


O Wakisaka, N Takahashi, T Shinohara, T … - Journal of Molecular and Cellular Cardiology, 2007 - Elsevier
We tested the hypothesis that atrial fibrosis and atrial fibrillation (AF)
evoked by angiotensin II (AII) could be prevented by the induction of heat-shock
protein 72 (HSP72) by hyperthermia (HT). In cultured atrial fibroblasts ...
Cited by 5 - Related articles - All 8 versions

Preconditioning effects of steroids and hyperoxia on cardiac ischemia–reperfusion injury and …

- ejcts.ch
ML Kaljusto, KO Stensløkken, T Mori, A … - European Journal of Cardio-Thoracic Surgery, 2008 - Elsevier
Objective: Corticosteroids and hyperoxia protect the heart against
ischemia–reperfusion injury and may attenuate vascular reactivity. We
hypothesized that (1) combining these two pretreatments induces an additive ...
Cited by 4 - Related articles - All 41 versions

Protection of the abnormal heart


C Pantos, I Mourouzis, DV Cokkinos - Heart failure reviews, 2007 - Springer
Abstract Myocardial ischemia and reperfusion injury have been extensively
investigated in the laboratory mainly in healthy tissues. However, in clinical
settings, ischemic heart disease coexists with certain illnesses, which ...
Cited by 3 - Related articles - BL Direct - All 4 versions


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