- ►diabetesjournals.org R Lehmann, RA Zuellig, P Kugelmeier, PB … - Diabetes, 2007 - Am Diabetes Assoc Many factors influence the outcome of islet transplantation. As islets in the
early posttransplant setting are supplied with oxygen by diffusion only and are
in a hypoxic state in the portal system, we tested whether small human ... Cited by 22 - Related articles - BL Direct - All 13 versions
- ►pubget.com [PDF] - Free from Publisher F Bertuzzi, C Ricordi - Diabetes Care, 2007 - Am Diabetes Assoc Graft function prediction is a work in progress. Initially, the best parameters
representative of engrafted islet mass in recipients should be defined. Fasting
C-peptide and exogenous insulin requirements are commonly used, although ... Cited by 19 - Related articles - All 7 versions
K Maedler - Diabetes Obesity and Metabolism, 2008 - interscience.wiley.com The healthy β-cell has an enormous capacity to adapt to conditions of higher
insulin demand (eg in obesity, pregnancy, cortisol excess) to maintain
normoglycaemia with an increase in its functional β-cell mass. This ... Cited by 7 - Related articles - BL Direct - All 4 versions
DM Salvay, CB Rives, X Zhang, F Chen, DB … - Transplantation, 2008 - pubmedcentral.nih.gov The survival and function of transplanted pancreatic islets is limited, owing in
part to disruption of islet-matrix attachments during the isolation procedure.
Using polymer scaffolds as a platform for islet transplantation, we ... Cited by 5 - Related articles - BL Direct - All 5 versions
JM Meier, A Alavi, S Iruvuri, S Alzeair, R … - Seminars in nuclear medicine, 2007 - Elsevier With the size of the aged population in the United States expected to grow
considerably during the next several decades, the number of imaging studies
performed on such aged individuals will similarly increase. Thus, it is ... Cited by 5 - Related articles - All 19 versions
SH Ihm, HJ Moon, JG Kang, CY Park, KW Oh, … - Diabetes Research and Clinical Practice, 2007 - Elsevier Recently, the glucose-stimulated insulin release of isolated human islets has
been shown to deteriorate progressively with advancing donor age. This decline
in beta cell function with aging may contribute to the increasing ... Cited by 4 - Related articles - All 8 versions
H Ichii, C Ricordi - Journal of Hepato-Biliary-Pancreatic Surgery, 2009 - Springer Abstract Despite substantial advances in islet isolation methods and
immunosuppressive protocol, pancreatic islet cell transplantation remains an
experimental procedure currently limited to the most severe cases of type 1 ... Cited by 4 - Related articles - All 2 versions
S Matsumoto, H Noguchi, B Naziruddin, N … - Proceedings (Baylor University. Medical Center), 2007 - pubmedcentral.nih.gov Pancreatic islet transplantation is a promising treatment for diabetes but still
faces several challenges. Poor islet isolation efficiency and poor long-term
insulin independence are currently two major issues, although donor ... Cited by 3 - Related articles - All 10 versions
LM Cree, SK Patel, A Pyle, S Lynn, DM … - Diabetologia, 2008 - Springer Abstract Aim/hypothesis Pancreatic beta cell function has been shown to decline
with age in man. Depletion of mitochon- drial DNA (mtDNA) copy number is
associated with impaired insulin secretion in pancreatic beta cell lines, ... Cited by 3 - Related articles - All 2 versions
M Zhao, P Muiesan, SA Amiel, P Srinivasan, H … - American Journal of Transplantation, 2007 - interscience.wiley.com Islets from brain-dead donors (BDDs) are being used in the treatment of Type 1
diabetes. However, both donor numbers and islet survival are limited. We
explored the clinical potential for islets from non-heart-beating donors ... Cited by 2 - Related articles - BL Direct - All 3 versions
