- ►diabetesjournals.org CJ Nolan, MSR Madiraju, V Delghingaro- … - Diabetes, 2006 - Am Diabetes Assoc Fatty acids (FAs) and other lipid molecules are important for many cellular
functions, including vesicle exocytosis. For the pancreatic β-cell, while the
presence of some FAs is essential for glucose-stimulated insulin secretion, ... Cited by 54 - Related articles - BL Direct - All 5 versions
- ►jneurosci.org S Speese, M Petrie, K Schuske, M Ailion, K … - Journal of Neuroscience, 2007 - Soc Neuroscience Previous studies indicated that CAPS (calcium-dependent activator protein for
secretion) functions as an essential component for the Ca 2+ -dependent
exocytosis of dense-core vesicles in neuroendocrine cells. However, recent ... Cited by 25 - Related articles - All 7 versions
D Sieburth, JM Madison, JM Kaplan - Nature Neuroscience, 2006 - nature.com The secretion of neurotransmitters and neuropeptides is mediated by distinct
organelles—synaptic vesicles (SVs) and dense-core vesicles (DCVs),
respectively. Relatively little is known about the factors that ... Cited by 23 - Related articles - BL Direct - All 3 versions
- ►shouxi.net EP Kwan, L Xie, L Sheu, T Ohtsuka, HY … - Diabetes, 2007 - Am Diabetes Assoc RESULTS—To determine which exocytotic steps caused by Munc13-1 deficiency are
rescued by Epac2 and PKA, we used patch-clamp capacitance measurements, showing
that 1) cAMP restored the reduced readily releasable pool (RRP) and ... Cited by 16 - Related articles - BL Direct - All 4 versions
- ►endojournals.org YM Leung, EP Kwan, B Ng, Y Kang, HY … - Endocrine reviews, 2007 - Endocrine Soc The three SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein
receptor) proteins, syntaxin, SNAP25 (synaptosome-associated protein of 25 kDa),
and synaptobrevin, constitute the minimal machinery for exocytosis in ... Cited by 16 - Related articles - BL Direct - All 3 versions
- ►endojournals.org M Prentki, SR Madiraju - Endocrine reviews, 2008 - Endocrine Soc GL/FFA cycle is referred to as a "futile" cycle because it involves continuous
formation and hydrolysis of GL with the release of heat, at the expense of ATP.
However, we present evidence underscoring the "vital" cellular signaling ... Cited by 14 - Related articles - All 5 versions
- ►fasebj.org J Chen, ST Hui, FM Couto, IN Mungrue, DB … - The FASEB Journal, 2008 - FASEB Pancreatic beta-cell loss through apoptosis represents a key factor in the
pathogenesis of diabetes; however, no effective approaches to block this process
and preserve endogenous beta-cell mass are currently available. To study ... Cited by 11 - Related articles - All 5 versions
B Ke, E Oh, DC Thurmond - Journal of Biological Chemistry, 2007 - ASBMB The widely expressed Sec/Munc18 (SM) protein Munc18c is required for
SNARE-mediated insulin granule exocytosis from islet beta cells and GLUT4
vesicle exocytosis in skeletal muscle and adipocytes. Although Munc18c ... Cited by 10 - Related articles - All 5 versions
- ►jimmunol.org C Pivot-Pajot, F Varoqueaux, G de Saint … - The Journal of Immunology, 2008 - Am Assoc Immnol The neutrophil plays a central role in the innate host immune defense. Regulated
exocytosis of its granules and release of antimicrobial and cytotoxic substances
are key events to limit the spread of pathogens. However, the molecular ... Cited by 7 - Related articles - BL Direct - All 2 versions