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Scholar Results 1 - 10 of about 55 citing Clerk: Obesity blunts insulin-mediated microvascular recruitment in human forearm muscle. (0.11 sec) 

Cardiovascular actions of insulin

- endojournals.org
R Muniyappa, M Montagnani, KK Koh, MJ … - Endocrine reviews, 2007 - Endocrine Soc
Insulin has important vascular actions to stimulate production of nitric oxide
from endothelium. This leads to capillary recruitment, vasodilation, increased
blood flow, and subsequent augmentation of glucose disposal in classical ...
Cited by 99 - Related articles - BL Direct - All 5 versions

Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, …

- physiology.org
R Muniyappa, S Lee, H Chen, MJ Quon - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc
Insulin resistance contributes to the pathophysiology of diabetes and is a
hallmark of obesity, metabolic syndrome, and many cardiovascular diseases.
Therefore, quantifying insulin sensitivity/resistance in humans and animal ...
Cited by 56 - Related articles - BL Direct - All 4 versions

Microvascular dysfunction: a potential pathophysiological role in the metabolic syndrome


EH Serne, RT de Jongh, EC Eringa, RG … - Hypertension, 2007 - Am Heart Assoc
Obesity and a central body fat distribution, hypertension, insulin resistance,
glucose intolerance, dyslipidemia, and proinflammatory and prothrombotic factors
are all part of the metabolic syndrome. The metabolic syndrome defines a ...
Cited by 29 - Related articles - All 7 versions

Tumor necrosis factor-{alpha} induces insulin resistance in endothelial cells via a p38 …

- endojournals.org
G Li, EJ Barrett, MO Barrett, W Cao, Z Liu - Endocrinology, 2007 - Endocrine Soc
Chronic inflammation contributes to vascular insulin resistance and endothelial
dysfunction. Systemic infusion of TNF- abrogates insulin's action to enhance
skeletal muscle microvascular perfusion. In skeletal muscle TNF- induces ...
Cited by 24 - Related articles - BL Direct - All 3 versions

Oral glucosamine for 6 weeks at standard doses does not cause or worsen insulin resistance …

- shouxi.net
R Muniyappa, RJ Karne, G Hall, SK Crandon, … - Diabetes, 2006 - Am Diabetes Assoc
Glucosamine is a popular nutritional supplement used to treat osteoarthritis.
Intravenous administration of glucosamine causes insulin resistance and
endothelial dysfunction. However, rigorous clinical studies evaluating the ...
Cited by 18 - Related articles - BL Direct - All 6 versions

Microcirculation and the metabolic syndrome


N Wiernsperger, P Nivoit, LGK De Aguiar, E … - Microcirculation, 2007 - informahealthcare.com
The present review, to the authors' knowledge, is the first to specifically
address the relationships between microcirculation and metabolic syndrome, a
cluster of metabolic and cardiovascular modifications highly prevalent in ...
Cited by 18 - Related articles - BL Direct - All 4 versions

p38 mitogen-activated protein kinase mediates palmitate-induced apoptosis but not inhibitor …

- endojournals.org
W Chai, Z Liu - Endocrinology, 2007 - Endocrine Soc
Plasma free fatty acids are elevated in patients with type 2 diabetes and
contribute to the pathogenesis of insulin resistance and endothelial
dysfunction. The p38 MAPK mediates stress, inflammation, and apoptosis. ...
Cited by 14 - Related articles - BL Direct - All 2 versions

Regulation of vascular function and insulin sensitivity by adipose tissue: focus on …


EC Eringa, W Bakker, YM Smulders, EH … - Microcirculation, 2007 - informahealthcare.com
Obesity is associated with insulin resistance, hypertension and cardiovascular
disease, but the mechanisms underlying these associations are incompletely
understood. Microvascular dysfunction may play an important role in the ...
Cited by 13 - Related articles - BL Direct - All 4 versions

[PDF] Microvascular dysfunction in obesity: a potential mechanism in the pathogenesis of obesity- …

- Free from Publisher
M Dysfunction, CDA Stehouwer - Physiology, 2007 - sochob.cl
Evidence from several studies indicates that obesity impairs microvascular
function in several ways. First, impairments of endothelial function of
different microvascular structures have been demonstrated in obesity. Obese ...
Cited by 13 - Related articles - View as HTML - BL Direct - All 6 versions

The renin-angiotensin system and insulin resistance


Z Liu - Current diabetes reports, 2007 - Springer
Introduction Type 2 diabetes accelerates atherosclerosis, which con- tributes
significant morbidity and mortality in this patient population. Although the
underlying mechanisms remain to be fully defined, many studies have ...
Cited by 12 - Related articles - BL Direct - All 3 versions


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