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Scholar Results 1 - 7 of 7 citing Kovacs: A functional Tyr1306Cys variant in LARG is associated with increased insulin action in vivo. (0.16 sec) 

SNAP: predict effect of non-synonymous polymorphisms on function

- nih.gov
Y Bromberg, B Rost - Nucleic Acids Research, 2007 - Oxford Univ Press
1 Department of Biochemistry and Molecular Biophysics, Columbia University, 630
West 168th Street, New York, NY 10032, USA, 2 Columbia University Center for
Computational Biology and Bioinformatics (C2B2), 1130 St. Nicholas Ave. Rm. ...
Cited by 35 - Related articles - All 13 versions

Diabetes-induced coronary vascular dysfunction involves increased arginase activity

- ahajournals.org [PDF] 
MJ Romero, DH Platt, HE Tawfik, M Labazi, … - Circulation Research, 2008 - Am Heart Assoc
Abstract—Increases in arginase activity have been reported in a variety of
disease conditions characterized by vascular dysfunction. Arginase competes with
NO synthase for their common substrate arginine, suggesting a cause and ...
Cited by 26 - Related articles - All 5 versions

Variants in ARHGEF11, a candidate gene for the linkage to type 2 diabetes on chromosome 1q …

- diabetesjournals.org
L Ma, RL Hanson, LN Que, AMG Cali, M Fu, JL … - Diabetes, 2007 - Am Diabetes Assoc
A prior genome-wide linkage scan in Pima Indians indicated a young-onset (aged
<45 years) type 2 diabetes susceptibility locus on chromosome 1q21-q23.
ARHGEF11, which encodes the Rho guanine nucleotide exchange factor 11, was ...
Cited by 3 - Related articles - BL Direct - All 8 versions

Rho exchange factors in the cardiovascular system


G Loirand, E Scalbert, A Bril, P Pacaud - Current opinion in pharmacology, 2008 - Elsevier
Increasing evidence has accumulated to implicate overactivation of Rho protein
as a common component for the pathogenesis of several cardiovascular disorders
including hypertension, coronary and cerebral vasospasm, atherosclerosis, ...
Cited by 1 - Related articles - All 3 versions

Determination of the “Amino Acid Conflicts” and amino acid substitutions in primary …


MA Kovalyova, LI Kovalyov, LS Eryomina, AA … - … Moscow) Supplemental Series B: Biomedical Chemistry, 2008 - Springer
Studies of human proteins started in the post- genomic era of biochemistry are
characterized by marked structural direction; these studies are closely
associated with studies of genes encoding these pro- teins [1, 2]. This ...
Related articles

Genetic variants in the leukemia-associated Rho guanine nucleotide exchange factor ( …

- eje-online.org
C Holzapfel, N Klopp, H Grallert, C Huth, C … - European Journal of Endocrinology, 2007 - EFES
Methods: Sequencing of Tyr1306Cys, which was of functional relevance in Pima
Indians, in 48 randomly selected individuals and genotyping of 11 additional
LARG SNPs in 1653 subjects were performed. Four linkage disequilibrium (LD) ...
Related articles - BL Direct - All 7 versions

LWW Journals


DCVD Involves, IA Activity - pt.wkhealth.com
From the Department of Pharmacology & Toxicology (MJR, DHP, HET, ABE-R., RWC),
Vascular Biology Center (ML, MB, RBC), and Department of Cellular Biology and
Anatomy (RBC), Medical College of Georgia, Augusta. ABE-R. is currently at ...
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