- ►fasebj.org V Bezaire, EL Seifert, ME Harper - The FASEB Journal, 2007 - FASEB Uncoupling protein (UCP) 3 (UCP3) is a mitochondrial anion carrier protein with
highly selective expression in skeletal muscle. Despite a great deal of
interest, to date neither its molecular mechanism nor its biochemical and ... Cited by 49 - Related articles - BL Direct - All 4 versions
- ►diabetesjournals.org M Vaxillaire, J Veslot, C Dina, C Proença, S … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— The GCK (Glucokinase) −30A allele was associated with increased
type 2 diabetes risk at the end of the follow-up study (adjusted OR 1.34 [95% CI
1.07–1.69]) under an additive model, as supported in independent French ... Cited by 34 - Related articles - BL Direct - All 4 versions
AJP Smith, JA Cooper, LK Li, SE Humphries - International Journal of Obesity, 2007 - nature.com A common polymorphism, rs7566605, 10 kb upstream of the insulin-induced gene 2
transcription start site has been associated with obesity in Caucasian and
African-American populations, with the hypothesis that an alteration in ... Cited by 29 - Related articles - BL Direct - All 3 versions
P Schrauwen - Proceedings of the Nutrition Society, 2007 - Cambridge Univ Press A high dietary fat intake and low physical activity characterize the current
Western lifestyle. Dietary fatty acids do not stimulate their own oxidation and
a surplus of fat is stored in white adipose tissue, liver, heart and ... Cited by 24 - Related articles - BL Direct - All 5 versions
- ►youngbiology.com [PDF] AC Gates, C Bernal-Mizrachi, SL Chinault, … - Cell metabolism, 2007 - Elsevier Age-related disease, not aging per se, causes most morbidity in older humans.
Here we report that skeletal muscle respiratory uncoupling due to UCP1
expression diminishes age-related disease in three mouse models. In a ... Cited by 10 - Related articles - All 8 versions
CB Chan, N Kashemsant - Biochemical Society Transactions, 2006 - biochemsoctrans.cn Abstract UCPs (uncoupling proteins) can regulate cellular ATP production by
uncoupling oxidative phosphoryl- ation. UCP2 is expressed in islet β-cells and
its induction reduces glucose-stimulated insulin secretion. Under ... Cited by 10 - Related articles - View as HTML - BL Direct - All 5 versions
EJ Brunner, M Kivimäki, DR Witte, DA Lawlor … - PLoS Med, 2008 - medicine.plosjournals.org We genotyped three tagging SNPs (CRP + 2302G > A; CRP + 1444T > C; CRP + 4899T >
G) in the CRP gene and measured serum CRP in 5,274 men and women at mean ages 49
and 61 y (Whitehall II Study). Homeostasis model assessment-insulin ... Cited by 10 - Related articles - Cached - All 9 versions
- ►unav.es [PDF] MC Ochoa, JL Santos, C Azcona, MJ Moreno- … - Molecular Genetics and Metabolism, 2007 - Elsevier A number of studies have yielded controversial results on the association
between polymorphisms in UCP2 and UCP3 genes with obesity and its comorbidities.
The discrepancy among studies might be partially explained by the lack of ... Cited by 8 - Related articles - All 3 versions
DR Gable, J Matin, R Whittall, H Cakmak, KW … - Annals of Human Genetics, 2007 - cardiologicomonzino.it Alterations in the secretion of adipokines may explain the link between obesity,
type 2 diabetes (T2DM) and coronary artery disease (CAD). These conditions have
been associated with variation in the adiponectin gene, although evidence ... Cited by 7 - Related articles - View as HTML - BL Direct - All 4 versions
- ►ahajournals.org A Muthumala, H Montgomery, J Palmen, JA … - Hypertension, 2007 - Am Heart Assoc The impact of the ACE I/D polymorphism on coronary heart disease (CHD) risk is
modest at most, however it may act as a modifier gene. ACE genotype was
determined in 2711 healthy middle-aged men (mean age 56 years) followed for ... Cited by 6 - Related articles - All 7 versions