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Scholar Results 1 - 10 of 10 citing Mas: Reversal of type 1 diabetes by engineering a glucose sensor in skeletal muscle. (0.08 sec) 

Immune responses to AAV in clinical trials

- bentham.org [PDF] 
F Mingozzi, KA High - Current gene therapy, 2007 - ingentaconnect.com
Page 1. 316 Current Gene Therapy, 2007, 7, 316-324 1566-5232/07 $50.00+.00 © 2007 Bentham
Science Publishers Ltd. Immune Responses to AAV in Clinical Trials Federico Mingozzi 1 and
Katherine A. High 1,2,* 1 Children's Hospital of Philadelphia, Philadelphia, PA, USA; ...
Cited by 37 - Related articles - BL Direct - All 7 versions

Immunity to adeno-associated virus vectors in animals and humans: a continued …


AK Zaiss, DA Muruve - Gene Therapy, 2008 - nature.com
Recombinant vectors based on adeno-associated virus (AAV) have been shown to stably express
many genes in vivo without mounting immune responses to vectors or transgenes. Thus, AAV
vectors have rapidly become the reagents of choice for therapeutic gene transfer. Yet one ...
Cited by 34 - Related articles - BL Direct - All 3 versions

Long-term suppression of experimental arthritis following intramuscular …


Z Sandalon, EM Bruckheimer, KH Lustig, H Burstein - Molecular Therapy, 2007 - nature.com
We previously reported that administration of an adeno-associated virus 2 (AAV2) vector encoding
a rat tumor necrosis factor (TNF) receptor–immunoglobulin Fc (TNFR:Fc) fusion gene to rats
with streptococcal cell wall-induced arthritis resulted in suppression of joint inflammation ...
Cited by 11 - Related articles - All 3 versions

Diabetes-induced alteration of F4/80+ macrophages: a study in mice with …


H Ma, G Liu, W Ding, Y Wu, L Cai, Y Zhao - Journal of Molecular Medicine, 2008 - Springer
Abstract Macrophages as an early stage of immune responses form a bridge between innate
and acquired immunity and shape the adaptive immune response. The immunoregulatory functions
of macrophages in hosts with a prolonged exposure to a diabetic milieu remain to be ...
Cited by 4 - Related articles - BL Direct - All 4 versions

Gene transfer to induce insulin production for the treatment of diabetes mellitus


DE Olson, PM Thulé - Expert Opin. Drug Deliv., 2008 - informahealthcare.com
Background: Gene transfer can induce insulin production from non-β-cells. Multiple gene transfer
protocols have demonstrated efficacy correcting diabetes-associated hyperglycemia and growth
abnormalities in vivo. Objectives: To review the literature reporting induction of insulin ...
Cited by 1 - Related articles - All 5 versions

Treatment of diabetes by transplantation of drug-inducible insulin-producing gut …


S Unniappan, RD Wideman, C Donald, V Gunn, JL … - Journal of Molecular …, 2009 - Springer
Page 1. ORIGINAL ARTICLE Treatment of diabetes by transplantation of drug-inducible
insulin-producing gut cells Suraj Unniappan & Rhonda D. Wideman & Christine Donald & Virginia
Gunn & Jennifer L. Wall & Qiu-Xia Zhang & Travis D. Webber & Anthony T. Cheung & ...
Cited by 1 - Related articles - All 2 versions

Glucose-and Metabolically Regulated Hepatic Insulin Gene Therapy for Diabetes


PYJ Hsu, RM Kotin, YW Yang - Pharmaceutical research, 2008 - Springer
Received November 14, 2007; accepted January 16, 2008; published online February 22, 2008
Purpose. The purpose of this study was to examine glucose- and metabolically modulation of
insulin secretion by rAAV-mediated gene delivery in vitro and in vivo. Materials and ...
Cited by 1 - Related articles - BL Direct - All 3 versions

15. Use of Extra-Pancreatic Tissues for Cell Replacement Therapy for Diabetes


I Meivar-Levy, S Ferber - Pancreatic Beta Cell in Health and Disease, 2007 - Springer
Summary. Pancreatic islet transplantation may constitute the best approach for the long-term
control of blood glucose levels in the treatment of diabetes. However, tissue replacement therapy
will become widely available as a treat- ment for diabetic patients only when islets or ...
Related articles - All 2 versions

[PDF] Preventive Interventions for Type 1 Diabetes: History, Appraisal and Prospects


JDMABMBC BSc, JLMMDMS FRCPC - CANADIAN JOURNAL OF …, 2007 - diabetes.ca
Putative therapeutic interventions with hypothetical clinical benefit in overt type 1 diabetes, or
in the pre-clinical condi- tion with evidence of the active autoimmune process, or in people at
risk for the disease by virtue of family history with or without genotypic evidence of ...
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[PDF] CONTRARESTACIÓ DE LA DIABETIS MELLITUS MITJANÇANT LA GENERACIÓ …


JM MOGAS - tdx.cbuc.es
Page 1. Departament de Bioquímica i Biologia Molecular de la FACULTAT DE VETERINÀRIA
CENTRE DE BIOTECNOLOGIA ANIMAL I TERÀPIA GÈNICA (CBATEG) CONTRARESTACIÓ
DE LA DIABETIS MELLITUS MITJANÇANT LA GENERACIÓ D'UN SENSOR DE LA ...
Related articles - All 8 versions


 


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