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Scholar Results 1 - 10 of about 47 citing Battaglia: Induction of tolerance in type 1 diabetes via both CD4+ CD25+ T regulatory cells.... (0.10 sec) 

Interleukin-10-secreting type 1 regulatory T cells in rodents and humans


MG Roncarolo, S Gregori, M Battaglia, R … - Immunol …, 2006 - interscience.wiley.com
Summary: Interleukin‐10 (IL‐10)‐secreting T regulatory type 1 (Tr1) cells are defined by their
specific cytokine production profile, which includes the secretion of high levels of IL‐10 and
transforming growth ...
Cited by 278 - Related articles - BL Direct - All 4 versions

Rapamycin promotes expansion of functional CD4+ CD25+ FOXP3+ regulatory T …

- jimmunol.org
M Battaglia, A Stabilini, B Migliavacca, J … - The Journal of …, 2006 - Am Assoc Immnol
CD4 + CD25 + FOXP3 + T regulatory cells (Tregs) are pivotal for the induction and maintenance of
peripheral tolerance in both mice and humans. Rapamycin has been shown to promote tolerance in
experimental models and to favor ...
Cited by 102 - Related articles - BL Direct - All 4 versions

Rapamycin-conditioned dendritic cells are poor stimulators of allogeneic CD4+ T …

- jimmunol.org
HR Turnquist, G Raimondi, AF Zahorchak, … - The Journal of …, 2007 - Am Assoc Immnol
The ability of dendritic cells (DC) to regulate Ag-specific immune responses via their influence on
T regulatory cells (Treg) may be key to their potential as therapeutic tools or targets for the
promotion/restoration of tolerance. ...
Cited by 59 - Related articles - All 4 versions

Is FOXP3 a bona fide marker for human regulatory T cells?


MG Roncarolo, S Gregori - European journal of immunology, 2008 - ncbi.nlm.nih.gov
FOXP3 is a specific marker for naturally occurring regulatory T cells (nTreg). FOXP3 expression is
correlated with development and function of nTreg. Recent evidence suggests that, upon activation,
human effector T (Teff) cells and ...
Cited by 34 - Related articles - BL Direct

CD4 T-regulatory cells: toward therapy for human diseases


SE Allan, R Broady, S Gregori, ME Himmel, N … - Immunological …, 2008 - pt.wkhealth.com
Acknowledgements: We thank Paul Orban for critical reading of the manuscript. The authors' own
research was supported by grants from the Canadian Institutes for Health Research (CIHR), the
National Cancer Institute of ...
Cited by 22 - Related articles - All 6 versions

In vivo imaging of T cell delivery to tumors after adoptive transfer therapy


MJ Pittet, J Grimm, CR Berger, T Tamura, … - Proceedings of the …, 2007 - National Acad Sciences
Adoptive transfer therapy of in vitro-expanded tumor-specific cytolytic T lymphocytes (CTLs) can
mediate objective cancer regression in patients. Yet, technical limitations hamper precise
monitoring of posttherapy T cell ...
Cited by 20 - Related articles - BL Direct - All 13 versions

Converting antigen-specific diabetogenic CD4 and CD8 T cells to TGF-beta …


J Peng, B Dicker, W Du, F Tang, P Nguyen, T Geiger, … - Journal of Autoimmunity, 2007 - Elsevier
Immuno-regulatory defects, including a reduction in the number and function of regulatory T cells,
play an important role in the development of autoimmune diabetes in both humans and non-obese
diabetic (NOD) mice. In this study ...
Cited by 17 - Related articles - All 4 versions

Rapamycin impairs in vivo proliferation of islet beta-cells

- diabetesresearch.org [PDF] 
E Zahr, RD Molano, A Pileggi, H Ichii, SS Jose, N … - Transplantation, 2007 - journals.lww.com
Transplantation. Wolters Kluwer Health Logo. All Issues. ...
Cited by 12 - Related articles - BL Direct - All 4 versions

Expansion and de novo generation of potentially therapeutic regulatory T cells in …


MS Longhi, F Meda, P Wang, M Samyn, G Mieli- … - Hepatology, 2008 - interscience.wiley.com
CD4+CD25+ regulatory T cells (T-regs) are central to the maintenance of immune tolerance and
represent an immune intervention candidate in autoimmune hepatitis (AIH), a condition characterized
by impaired T-reg number and ...
Cited by 12 - Related articles - BL Direct - All 2 versions

The Janus Face of CD4CD25 Regulatory T Cells in Cancer and Autoimmunity


S Danese, S Rutella - Current medicinal chemistry, 2007 - ingentaconnect.com
Abstract: Regulatory T cells (Treg) encompass a heterogeneous family of T cells implicated in
maintenance of tolerance to self antigens. Treg cells might be qualitatively and/or quantitatively
deficient in human autoimmune ...
Cited by 12 - Related articles - BL Direct - All 5 versions


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