- ►endojournals.org AM Sharma, B Staels - Journal of Clinical Endocrinology & Metabolism, 2007 - Endocrine Soc Conclusions: PPAR is highly expressed in adipose tissue, where its activation with thiazolidinediones
alters fat topography and adipocyte phenotype and up-regulates genes involved in fatty acid
metabolism and triglyceride storage. Furthermore, PPAR activation is associated with ... Cited by 99 - Related articles - BL Direct - All 3 versions
B Gross, B Staels - Best Practice & Research Clinical Endocrinology & …, 2007 - Elsevier Patients with type-2 diabetes mellitus (T2DM) are considered to be at particularly high risk for
cardiovascular disease. Over the last decade, the members of the peroxisome proliferator-activated
receptor (PPAR) subfamily of nuclear receptors have emerged as valuable ... Cited by 21 - Related articles - All 15 versions
S Piteau, A Olver, SJ Kim, K Winter, JA Pospisilik, F … - … and Biophysical Research …, 2007 - Elsevier In type 2 diabetes (T2DM) β-cell responsiveness to glucose-dependent insulinotropic polypeptide
(GIP) is reduced. In a model of T2DM, the VDF Zucker rat, GIP receptor mRNA and protein levels
were shown to be down-regulated. Possible restoration of responsiveness to GIP in ... Cited by 12 - Related articles - All 4 versions
JC Fruchart, F Sacks, MP Hermans, G Assmann, … - The American Journal of …, 2008 - Elsevier Despite achieving targets for low-density lipoprotein (LDL) cholesterol, blood pressure, and glycemia
in accordance with current standards of care, patients with dyslipidemia remain at high residual
risk of vascular events. Atherogenic dyslipidemia, characterized by elevated triglycerides ... Cited by 13 - Related articles - All 7 versions
- ►diabetesjournals.org L Andrulionytė, T Kuulasmaa, JL Chiasson, M Laakso - Diabetes, 2007 - Am Diabetes Assoc Peroxisome proliferator–activated receptor (PPAR) α, a transcription factor of the nuclear receptor
superfamily, regulates fatty acid oxidation. We evaluated the association of single nucleotide
polymorphisms (SNPs) of the PPAR-α gene (PPARA) with the conversion from impaired ... Cited by 9 - Related articles - BL Direct - All 4 versions
- ►physiology.org [PDF] X Ruan, F Zheng, Y Guan - American Journal of Physiology- …, 2008 - Am Physiological Soc 215 articles, 104 of which you can access free at: This article cites http://ajprenal.physiology.org
/cgi/content/full/294/5/F1032#BIBL ... 1 other HighWire hosted article: This article has been cited
by ... [PDF] [Full Text] [Abstract] , October 1, 2008; 295 (4): F942-F949. Am J Physiol ... Cited by 10 - Related articles - BL Direct - All 3 versions
- ►jbc.org GA Martens, A Vervoort, M Van de Casteele, G … - Journal of Biological …, 2007 - ASBMB A loss-of-function mutation of the mitochondrial -oxidation enzyme L-3-hydroxyacyl-CoA
dehydrogenase, short chain (HADHSC), has been associated with hyperinsulinemic hypoglycemia
in man. It is still unclear whether loss of glucose homeostasis in these patients (partly) ... Cited by 7 - Related articles - All 7 versions
AC Carpentier - Diabetes and Metabolism, 2008 - Elsevier Insulin resistance (IR) and impaired glucose-stimulated insulin secretion (GSIS) are the two primary
pathophysiological abnormalities leading to the development of type 2 diabetes (T2D). Over
the past two decades, a large body of work has implicated enhanced delivery of fatty ... Cited by 8 - Related articles - BL Direct - All 2 versions
- ►endojournals.org Y Sun, L Zhang, HF Gu, W Han, M Ren, F Wang, B … - Endocrinology, 2008 - Endocrine Soc Both peroxisome proliferator-activated receptor- (PPAR ) and pancreatic/duodenal
homeobox-1 (PDX-1) have been reported to be associated with glucose-stimulated insulin secretion
(GSIS), but the relationship between PPAR and PDX-1 is not yet fully understood. In the ... Cited by 6 - Related articles - BL Direct - All 3 versions
