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Scholar Results 1 - 10 of about 47 citing Menini: Deletion of p66Shc longevity gene protects against experimental diabetic glomerulopathy.... (0.11 sec) 

Genetic deletion of p66Shc adaptor protein prevents hyperglycemia-induced endothelial …


GG Camici, M Schiavoni, P Francia, M … - Proceedings of the National Academy of Sciences, 2007 - National Acad Sciences
Increased production of reactive oxygen species (ROS) and loss of endothelial NO
bioavailability are key features of vascular disease in diabetes mellitus. The
p66 Shc adaptor protein controls cellular responses to oxidative stress. ...
Cited by 44 - Related articles - BL Direct - All 10 versions

Wnt/beta-catenin signaling modulates survival of high glucose-stressed mesangial cells

- asnjournals.org
CL Lin, JY Wang, YT Huang, YH Kuo, K … - Journal of the American Society of Nephrology, 2006 - Am Soc Nephrol
Glomerulosclerosis and diabetic nephropathy are attributable to high glucose
induction of mesangial cell apoptosis. Whereas Wnt signaling has been found to
regulate renal morphogenesis and pathogenesis, the biologic role of Wnt/ - ...
Cited by 35 - Related articles - BL Direct - All 6 versions

Reduced oxidant stress and extended lifespan in mice exposed to a low glycotoxin diet: …

- amjpathol.org
W Cai, JC He, L Zhu, X Chen, S Wallenstein, … - American Journal of Pathology, 2007 - ASIP
Aging is accompanied by increased oxidative stress (OS) and accumulation of
advanced glycation end products (AGEs). AGE formation in food is
temperature-regulated, and ingestion of nutrients prepared with excess heat ...
Cited by 30 - Related articles - BL Direct - All 5 versions

Efficient HIV-1 transmission from macrophages to T cells across transient virological …

- hematologylibrary.org [PDF] 
F Groot, S Welsch, QJ Sattentau - Blood, 2008 - bloodjournal.hematologylibrary.org
. Hematology; all rights reserved Copyright 2007 by The American Society of DC
20036. by the American Society of Hematology, 1900 M St, NW, Suite 200,
Washington Blood (print ISSN 0006-4971, online ISSN 1528-0020), is ...
Cited by 17 - Related articles - BL Direct - All 7 versions

Final common molecular pathways of aging and cardiovascular disease: role of the p66Shc …

- ahajournals.org
F Cosentino, P Francia, GG Camici, PG … - Arteriosclerosis, Thrombosis, and Vascular Biology, 2008 - Am Heart Assoc
Oxidative stress affects the availability of key-regulators of vascular
homeostasis and controls a number of signaling pathways relevant to myocardial
and vascular disease. Reactive oxygen species are generated by different ...
Cited by 15 - Related articles - All 6 versions

Increased glomerular cell (podocyte) apoptosis in rats with streptozotocin-induced diabetes …


S Menini, C Iacobini, G Oddi, C Ricci, P … - Diabetologia, 2007 - Springer
Abstract Aims/hypothesis Podocyte loss by apoptosis, in addition to favouring
progression of established diabetic nephropathy, has been recently indicated as
an early phenomenon triggering the initiation of glomerular lesions. This ...
Cited by 12 - Related articles - BL Direct - All 2 versions

Oral glycotoxins determine the effects of calorie restriction on oxidant stress, age-related …

- amjpathol.org
W Cai, JC He, L Zhu, X Chen, F Zheng, GE … - American Journal of Pathology, 2008 - ASIP
We previously showed that the content of advanced glycation end products (AGEs)
in the diet correlates with serum AGE levels, oxidant stress (OS), organ
dysfunction, and lifespan. We now show that the addition of a chemically ...
Cited by 13 - Related articles - All 6 versions

Role of the GH/IGF-1 axis in lifespan and healthspan: Lessons from animal models


DE Berryman, JS Christiansen, G Johannsson … - Growth Hormone & IGF Research, 2008 - Elsevier
Animal models are fundamentally important in our quest to understand the
genetic, epigenetic, and environmental factors that contribute to human aging.
In comparison to humans, relatively short-lived mammals are useful models ...
Cited by 9 - Related articles - All 2 versions

Ablation of the gene encoding p66 Shc protects mice against AGE-induced glomerulopathy …


S Menini, C Iacobini, C Ricci, G Oddi, C Pesce … - Diabetologia, 2007 - Springer
Page 1. ARTICLE Ablation of the gene encoding p66 Shc protects mice against
AGE-induced glomerulopathy by preventing oxidant-dependent ...
Cited by 9 - Related articles - BL Direct - All 4 versions

p66Shc-generated oxidative signal promotes fat accumulation

- prepobedia.org [PDF] 
I Berniakovich, M Trinei, M Stendardo, E … - Journal of Biological Chemistry, 2008 - ASBMB
Reactive oxygen species (ROS) and insulin signaling in the adipose tissue are
critical determinants of aging and age-associated diseases. It is not clear,
however, if they represent independent factors or they are mechanistically ...
Cited by 9 - Related articles - All 4 versions


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