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Scholar Results 1 - 10 of 12 citing Lin: Kir6. 2 Mutations Associated With Neonatal Diabetes Reduce Expression of ATP-Sensitive.... (0.07 sec) 

Neonatal diabetes mellitus

- endojournals.org
L Aguilar-Bryan, J Bryan - Endocrine Reviews, 2008 - Endocrine Soc
An explosion of work over the last decade has produced insight into the multiple
hereditary causes of a nonimmunological form of diabetes diagnosed most
frequently within the first 6 months of life. These studies are providing ...
Cited by 15 - Related articles - BL Direct - All 6 versions

Sulfonylureas correct trafficking defects of disease-causing ATP-sensitive potassium …

- jbc.org
FF Yan, J Casey, SL Shyng - Journal of Biological Chemistry, 2006 - ASBMB
ATP-sensitive potassium (K ATP ) channels mediate glucose-induced insulin
secretion by coupling metabolic signals to -cell membrane potential and the
secretory machinery. Reduced K ATP channel expression caused by mutations ...
Cited by 13 - Related articles - All 6 versions

Congenital Hyperinsulinism–Associated ABCC8 Mutations That Cause Defective Trafficking …

- diabetesjournals.org
FF Yan, YW Lin, C MacMullen, A Ganguly, CA … - Diabetes, 2007 - Am Diabetes Assoc
Congenital hyperinsulinism (CHI) is a disease characterized by persistent
insulin secretion despite severe hypoglycemia. Mutations in the pancreatic
ATP-sensitive K + (K ATP ) channel proteins sulfonylurea receptor 1 (SUR1) ...
Cited by 8 - Related articles - BL Direct - All 5 versions

Destabilization of ATP-sensitive potassium channel activity by novel KCNJ11 mutations …

- nih.gov
YW Lin, JD Bushman, FF Yan, S Haidar, C … - Journal of Biological Chemistry, 2008 - ASBMB
The inwardly rectifying potassium channel Kir6.2 is the pore-forming subunit of
the ATP-sensitive potassium (K ATP ) channel, which controls insulin secretion
by coupling glucose metabolism to membrane potential in β-cells. Loss of ...
Cited by 4 - Related articles - All 4 versions

Update of mutations in the genes encoding the pancreatic beta-cell K (ATP) channel …


SE Flanagan, S Clauin, C Bellanné-Chantelot, … - Hum Mutat, 2009 - interscience.wiley.com
The beta-cell ATP-sensitive potassium (K ATP ) channel is a key component of
stimulus-secretion coupling in the pancreatic beta-cell. The channel couples
metabolism to membrane electrical events bringing about insulin secretion. ...
Cited by 4 - Related articles - All 3 versions

Islet-specific antibody seroconversion in patients with long duration of permanent …

- diabetesjournals.org
A Gach, K Wyka, MT Malecki, A Noczynska, J … - Diabetes Care, 2007 - Am Diabetes Assoc
Heterozygous activating mutations in the KCNJ11 gene are a common cause of
permanent neonatal diabetes (PNDM) (1,2). In contrast to the autoimmune type 1
diabetes, patients with KCNJ11 mutations do not have serological markers of ...
Cited by 4 - Related articles - BL Direct - All 4 versions

Sulfonylurea receptor 1 mutations that cause opposite insulin secretion defects with …


EB Pratt, FF Yan, JW Gay, CA Stanley, SL … - Journal of Biological Chemistry, 2009 - ASBMB
The β-cell ATP-sensitive potassium (K ATP ) channel composed of sulfonylurea
receptor SUR1 and potassium channel Kir6.2 serves a key role in insulin
secretion regulation by linking glucose metabolism to cell excitability. ...
Cited by 1 - Related articles - All 3 versions

Congenital hyperinsulinism-associated ABCC8 mutations that cause defective trafficking of …

- diabetesjournals.org [PDF] 
FF Yan, YW Lin, C MacMullen, A Ganguly, CA … - Diabetes, 2007 - Am Diabetes Assoc
Page 1. 1 Congenital hyperinsulinism-associated ABCC8 mutations that cause defective
trafficking of ATP-sensitive potassium channels: identification and rescue ...
Cited by 1 - Related articles - All 2 versions

Identification and Rescue


FF Yan, YW Lin, C MacMullen, A Ganguly, CA … - DIABETES, 2007 - Am Diabetes Assoc
C ongenital hyperinsulinism (CHI) of infancy is characterized by inappropriate
insulin secretion in the face of severe hypoglycemia in neonates and infants
(1–4). Clinical treatments involving the use of diazoxide or somatostatin ...
Related articles

Islet specific antibodies seroconversion in patients with long duration of permanent …


MD Mlynarski, P Wroclaw, W Mlynarski - Diabetes Care - Am Diabetes Assoc
Agnieszka Gach MD1, Krystyna Wyka Ph.D.1, Maciej T. Malecki MD, Ph.D.2, Anna
Noczynska MD, Ph.D.3, Jan Skupien MD2, Joanna Nazim MD, Ph.D.4, Mieczyslaw
Szalecki MD, Ph.D.5, Jerzy Bodalski MD, Ph.D.1, Jacek Sieradzki MD, Ph.D. ...
Related articles - All 3 versions


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