- ►nih.gov YC Long, JR Zierath - Journal of Clinical Investigation, 2006 - Am Soc Clin Investig AMP-activated protein kinase (AMPK) is an energy sensor that regulates cellular
metabolism. When activated by a deficit in nutrient status, AMPK stimulates glucose uptake and
lipid oxidation to produce energy, while turning off energy-consuming processes ... Cited by 166 - Related articles - BL Direct - All 9 versions
- ►diabetesjournals.org A Sriwijitkamol, DK Coletta, E Wajcberg, GB Balbontin, … - Diabetes, 2007 - Am Diabetes Assoc Activation of AMP-activated protein kinase (AMPK) by exercise induces several cellular processes
in muscle. Exercise activation of AMPK is unaffected in lean (BMI ∼25 kg/m 2 ) subjects with
type 2 diabetes. However, most type 2 diabetic subjects are obese (BMI >30 kg/m 2 ), and ... Cited by 51 - Related articles - BL Direct - All 4 versions
- ►physiology.org J Eliasson, T Elfegoun, J Nilsson, R … - American Journal of …, 2006 - Am Physiological Soc The aim of this study was to compare the training stimuli of eccentric (lengthening) and concentric
(shortening) contractions regarding the effect on signaling enzymes involved in protein
synthesis. Ten male subjects performed 4 x 6 maximal eccentric contractions on one leg ... Cited by 47 - Related articles - BL Direct - All 5 versions
- ►cell.com H Sano, L Eguez, MN Teruel, M Fukuda, TD Chuang, … - Cell Metabolism, 2007 - Elsevier GLUT4 trafficking to the plasma membrane of muscle and fat cells is regulated by insulin. An
important component of insulin-regulated GLUT4 distribution is the Akt substrate AS160 rab
GTPase-activating protein. Here we show that Rab10 functions as a downstream target of ... Cited by 44 - Related articles - All 7 versions
FSL Thong, PJ Bilan, A Klip - Diabetes, 2007 - Am Diabetes Assoc Insulin-dependent phosphorylation of Akt target AS160 is required for GLUT4 translocation. Insulin
and platelet-derived growth factor (PDGF) (Akt activators) or activation of conventional/novel
(c/n) protein kinase C (PKC) and 5′ AMP-activated protein kinase (AMPK) all promote a ... Cited by 43 - Related articles - BL Direct - All 5 versions
- ►uidaho.edu [PDF] DJ O'Gorman, HKR Karlsson, S McQuaid, O Yousif, Y … - Diabetologia, 2006 - Springer Page 1. ARTICLE Exercise training increases insulin-stimulated glucose disposal and GLUT4
(SLC2A4) protein content in patients with type 2 diabetes DJ O'Gorman & HKR Karlsson &
S. McQuaid & O. Yousif & Y. Rahman & D. Gasparro & S. Glund & ... Cited by 40 - Related articles - BL Direct - All 4 versions
JA Hawley, SJ Lessard - Acta Physiologica, 2008 - interscience.wiley.com Individuals with insulin resistance are characterized by impaired insulin action on whole-body
glucose uptake, in part due to impaired insulin-stimulated glucose uptake into skeletal
muscle. A single bout of exercise increases skeletal muscle glucose uptake via an insulin- ... Cited by 36 - Related articles - BL Direct - All 3 versions
EB Taylor, D An, HF Kramer, H Yu, NL Fujii, KSC … - Journal of Biological …, 2008 - ASBMB The Akt substrate of 160 kDa (AS160) is phosphorylated on Akt substrate (PAS) motifs in response
to insulin and contraction in skeletal muscle, regulating glucose uptake. Here we discovered
a dissociation between AS160 protein expression and apparent AS160 PAS ... Cited by 34 - Related articles - All 6 versions
GD Cartee, JFP Wojtaszewski - Applied Physiology, Nutrition, …, 2007 - article.pubs.nrc-cnrc.gc.ca Abstract: Insulin and exercise, the most important physiological stimuli to increase glucose transport
in skeletal muscle, trigger a redistribution of GLUT4 glucose transporter proteins from the cell
interior to the cell surface, thereby increasing glucose transport capacity. The most distal ... Cited by 26 - Related articles - Cached - BL Direct - All 4 versions
- ►physiology.org JT Treebak, JB Birk, AJ Rose, B Kiens, EA … - American Journal of …, 2007 - Am Physiological Soc We investigated time- and intensity-dependent effects of exercise on phosphorylation of Akt substrate
of 160 kDa (AS160) in human skeletal muscle. Subjects performed cycle exercise for 90 min
(67% O 2 peak , n = 8), 20 min (80% O 2 peak , n = 11), 2 min (110% of peak work rate, n ... Cited by 26 - Related articles - BL Direct - All 4 versions
