L Agius - Best Practice & Research Clinical Endocrinology & …, 2007 - Elsevier Type-2 diabetes is associated with impaired glucose clearance by the liver in
the postprandial state, and with elevated glucose production in the
post-absorptive state. New targets within the liver are currently being ... Cited by 17 - Related articles - All 17 versions
IR Kelsall, S Munro, I Hallyburton, JL … - FEBS letters, 2007 - Elsevier The inhibition of hepatic glycogen-associated protein phosphatase-1 (PP1-G L )
by glycogen phosphorylase a prevents the dephosphorylation and activation of
glycogen synthase, suppressing glycogen synthesis when glycogenolysis is ... Cited by 8 - Related articles - All 6 versions
- ►aspetjournals.org DJ Baker, D Constantin-Teodosiu, SW Jones, … - Journal of Pharmacology and Experimental …, 2006 - ASPET Decrements in skeletal muscle mass and functional capacity in response to
cachexia, postoperative inactivity, and sarcopenia (Busquets et al., 2004 Go ;
Ryall et al., 2004 Go ) have a negative impact on quality of life. The ... Cited by 5 - Related articles - BL Direct - All 5 versions
L Somsak, K Czifrak, M Toth, E Bokor, ED … - Current medicinal chemistry, 2008 - ingentaconnect.com 1 Department of Organic Chemistry, University of Debrecen, POB 20, H-4010
Debrecen, Hungary 2 Institute of Organic & Pharmaceutical Chemistry, The
National Hellenic Research Foundation, 48 Vassileos Constan- tinou Avenue, ... Cited by 3 - Related articles - All 3 versions
D Constantin-Teodosiu, DJ Baker, D … - The Journal of Physiology, 2009 - Physiological Soc We have recently shown that PPAR agonism, used clinically to treat insulin
resistance, increases fat oxidation and up-regulates mitochondrial PDK4 mRNA and
protein expression in resting skeletal muscle. We hypothesized that PDK4 up- ... Cited by 1 - Related articles - All 5 versions
SM Poucher, S Freeman, SJG Loxham, G Convey … - British Journal of Pharmacology, 2007 - pubmedcentral.nih.gov In rat primary hepatocytes, GPi688 inhibited glucagons-mediated glucose output
in a concentration dependent manner. Additionally GP activity was reduced and GS
activity increased seven-fold. GPi688 inhibited glucagon-mediated ... Cited by 1 - Related articles - BL Direct - All 3 versions
SS Schweiker, WA Loughlin, CL Brown, GK … - Journal of Peptide Science, 2009 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Related articles - All 2 versions
DJ Baker, D Constantin-Teodosiu, SW Jones, … - THE JOURNAL OF PHARMACOLOGY AND … - ASPET ABSTRACT Discovering approaches to maintain or improve muscle func- tion
(fatigue resistance) in patients with cachexia, postoperative weakness, and
sarcopenia is of clinical importance. 2-Agonist treatment increases muscle ...
ZH Israili - American Journal of Therapeutics, 2009 - pdfs.journals.lww.com There is a rising worldwide prevalence of diabetes, especially type 2 diabetes
mellitus (T2DM), which is one of the most challenging health problems in the
21st century. The associated complications of diabetes, such as ... Related articles - All 4 versions
IR Kelsall, D Rosenzweig, PTW Cohen - Cellular Signalling, 2009 - Elsevier Type 2 diabetes is characterised by elevated blood glucose concentrations, which
potentially could be normalised by stimulation of hepatic glycogen synthesis.
Under glycogenolytic conditions, the interaction of hepatic ... Related articles - All 2 versions