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Scholar Results 1 - 10 of 12 citing Ek: A Novel− 192c/g Mutation in the Proximal P2 Promoter of the Hepatocyte Nuclear Factor-4α.... (0.12 sec) 

A Hepatocyte Nuclear Factor-4α Gene (HNF4A) P2 Promoter Haplotype Linked With Late- …


H Ræder, L Bjørkhaug, S Johansson, K … - Diabetes, 2006 - Am Diabetes Assoc
Variants in hepatocyte nuclear factor (HNF)-4α cause maturity-onset diabetes of
the young, type 1 (MODY1) and may also be risk factors for type 2 diabetes. We
sequenced the HNF4A gene of 95 MODY3-negative probands from the Norwegian ...
Cited by 19 - Related articles - BL Direct - All 4 versions

The diabetic phenotype in HNF4A mutation carriers is moderated by the expression of …

- diabetesjournals.org
LW Harries, JM Locke, B Shields, NA Hanley, … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—HNF4A was expressed exclusively from the P2 promoter in adult
pancreas, but from 9 weeks until at least 26 weeks after conception, up to 23%
of expression in fetal pancreas was of P1 origin. HNF4A4–6 transcripts ...
Cited by 9 - Related articles - All 6 versions

Population-specific risk of type 2 diabetes conferred by HNF4A P2 promoter variants: a lesson …

- diabetesjournals.org
I Barroso, J Luan, E Wheeler, P Whittaker, … - Diabetes, 2008 - Am Diabetes Assoc
OBJECTIVE—Single nucleotide polymorphisms (SNPs) in the P2 promoter region of
HNF4A were originally shown to be associated with predisposition for type 2
diabetes in Finnish, Ashkenazi, and, more recently, Scandinavian ...
Cited by 7 - Related articles - All 8 versions

HNF4A genetic variants: role in diabetes


L Love-Gregory, MA Permutt - Current Opinion in Clinical Nutrition & Metabolic Care, 2007 - journals.lww.com
Purpose of review: Variants in the hepatocyte nuclear factor 4α (HNF4A) gene
play a role in the development of diabetes mellitus. Although genetic variation
in and around HNF4A regulatory regions has received considerable attention, ...
Cited by 6 - Related articles - BL Direct - All 5 versions

Alternate mRNA processing of the hepatocyte nuclear factor genes and its role in …


LW Harries - Expert Review of Endocrinology and Metabolism, 2006 - ingentaconnect.com
Variation in mRNA processing has the capacity to exert fine control over gene
expression in most cell types. The hepatic nuclear factor genes, like
approximately 74% of the genome, produce multiple transcripts. Hepatic ...
Cited by 3 - Related articles - All 3 versions

[PDF] To be presented by permission of the Faculty of Medicine of the University of Kuopio for …


L ANDRULIONYTĖ - uku.fi
To be presented by permission of the Faculty of Medicine of the University of
Kuopio ... Distributor: Kuopio University Library PO Box 1627 FI-70211 KUOPIO
FINLAND Tel. +358 17 163 430 Fax +358 17 163 410 www.uku.fi/kirjasto/ ...
Related articles

Population-specific risk of type 2 diabetes (T2D) conferred by HNF4A P2 promoter variants: a …


M Delgado, RJ Neuman, J Zhao, R Sherva, B … - Diabetes - Am Diabetes Assoc
Page 1. Population-specific risk of type 2 diabetes (T2D) conferred by HNF4A
P2 promoter variants: a lesson for replication studies ...

[PDF] Molecular genetics of monogenetic beta-cell diabetes


… , S Kooptiwut, N Plengvidhya, N Banchuin, P … - gst.sci.ku.ac.th
Page 1. Thai Journal of Genetics 2008, 1(2) : 93 › 108 Molecular genetics
of monogenetic beta-cell diabetes Jatuporn Sujjitjoon ...
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The diabetic phenotype in HNF4A mutation carriers is moderated by the expression of HNF4A …


LWH PhD, JML MBiol, BS PhD, NAH PhD, … - Am Diabetes Assoc
1Institute of Biomedical and Clinical Sciences, Peninsula Medical School,
Exeter, UK. 2Centre for Human Development, Stem Cells & Regeneration; Human
Genetics Division, University of Southampton, Southampton, UK. 3Department ...
Related articles

[PDF] A Lesson for Replication Studies


E Zeggini, MN Weedon, S Hunt, R Venkatesh, … - Diabetes, 2008 - Am Diabetes Assoc
Inês Barroso,1 Jian'an Luan,2 Eleanor Wheeler,1 Pamela Whittaker,1 Jon Wasson,3
Eleftheria Zeggini,4,5 Michael N. Weedon,6 Sarah Hunt,1 Ranganath Venkatesh,1
Timothy M. Frayling,6 Marcos Delgado,1,4 Rosalind J. Neuman,3 Jinghua ...


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