- ►diabetesjournals.org JA Emamaullee, L Stanton, C Schur, AM … - Diabetes, 2007 - Am Diabetes Assoc Islet transplantation can provide insulin independence in patients with type 1
diabetes, but islets derived from two or more donors are often required. A
significant fraction of the functional islet mass is lost to apoptosis in ... Cited by 21 - Related articles - BL Direct - All 5 versions
D vanderwindt, R Bottino, A Casu, N … - Xenotransplantation, 2007 - interscience.wiley.com Abstract: Islets isolated from multiple pancreas donors are often necessary to
achieve euglycemia in type 1 diabetic patients treated by islet
allotransplantation. This increases the burden on the limited pool of donor ... Cited by 17 - Related articles - BL Direct - All 3 versions
D Melloul - Biochemical Society Transactions, 2008 - biochemsoctrans.org Apoptotic β-cell death appears to be central to the pathogenesis of Type 1
diabetes mellitus and in islet graft rejection. The β-cell destruction is
partially mediated by cytokines, such as IL-1β (interleukin 1β), TNFα ... Cited by 8 - Related articles - Cached - BL Direct - All 4 versions
JI Stagner, HL Rilo, KK White - JOP. J Pancreas (Online), 2007 - joplink.net Context The availability of islet transplantation is limited by both the number
of donor pancreata and the number of islets required for successful
transplantation. There is evidence that the liver presents a less than ... Cited by 8 - Related articles - Cached - All 3 versions
- ►asnjournals.org DA Thomas, C Stauffer, K Zhao, H Yang, VK … - Journal of the American Society of Nephrology, 2007 - Am Soc Nephrol Apoptotic cell death is a defined pathway for islet cell demise, and
mitochondrial dysfunction contributes to islet cell apoptosis. The hypothesis
that the novel peptide d-Arg-2', 6'-dimethyltyrosine-Lys-Phe-NH 2 (SS-31), ... Cited by 7 - Related articles - BL Direct - All 5 versions
- ►endojournals.org X Huang, DJ Moore, RJ Ketchum, CS … - Endocrine Reviews, 2008 - Endocrine Soc Although type 1 diabetes cannot be prevented or reversed, replacement of insulin
production by transplantation of the pancreas or pancreatic islets represents a
definitive solution. At present, transplantation can restore euglycemia, ... Cited by 5 - Related articles - All 4 versions
- ►diabetesjournals.org D Su, N Zhang, J He, S Qu, S Slusher, R … - Diabetes, 2007 - Am Diabetes Assoc Successful islet transplantation depends on the infusion of sufficiently large
quantities of islets, but only a small fraction of implanted islets become
engrafted. The underlying mechanisms remain elusive. To probe the mechanism ... Cited by 5 - Related articles - BL Direct - All 4 versions
SA Sarkar, J Gunter, R Bouchard, JEB Reusch … - Diabetologia, 2007 - Springer Page 1. ARTICLE Dominant negative mutant forms of the cAMP response element
binding protein induce apoptosis and decrease the anti ... Cited by 6 - Related articles - BL Direct - All 4 versions
DD Paula, MVLB Bentley, RI Mahato - Journal of drug targeting, 2007 - informahealthcare.com Methods: Rat insulinoma INS-1E cells were transfected with chemically
synthesized siRNA after complex formation with Lipofectamine 2000. Cells were
then treated with a cocktail of inflammatory cytokines (IL-1β+ TNF-α+ ... Cited by 6 - Related articles - BL Direct - All 6 versions
NV Evgenov, J Pratt, P Pantazopoulos, A … - Transplantation, 2008 - journals.lww.com Skip Navigation Links Home > April 27, 2008 - Volume 85 - Issue 8 > Effects of
Glucose Toxicity and Islet Purity on In Vivo Magn... ... Molecular Imaging
Laboratory, MGH/MIT/HMS Athinoula A. Martinos Center for Biomedical ... Cited by 3 - Related articles - BL Direct - All 3 versions
