M Furuhashi, G Tuncman, CZ Görgün, L … - Nature, 2007 - nature.com Adipocyte fatty-acid-binding protein, aP2 (FABP4) is expressed in adipocytes and
macrophages, and integrates inflammatory and metabolic responses. Studies in
aP2-deficient mice have shown that this lipid chaperone has a significant ... Cited by 78 - Related articles - BL Direct - All 5 versions
- ►nih.gov H Cao, K Gerhold, JR Mayers, MM Wiest, SM … - Cell, 2008 - Elsevier Dysregulation of lipid metabolism in individual tissues leads to systemic
disruption of insulin action and glucose metabolism. Utilizing quantitative
lipidomic analyses and mice deficient in adipose tissue lipid chaperones ... Cited by 41 - Related articles - All 7 versions
- ►onmedic.net [PDF] M Laclaustra, D Corella, JM Ordovas - Nutrition, Metabolism and Cardiovascular Diseases, 2007 - Elsevier Several pathophysiological explanations for the metabolic syndrome have been
proposed involving insulin resistance, chronic inflammation and ectopic fat
accumulation following adipose tissue saturation. However, current concepts ... Cited by 38 - Related articles - All 25 versions
- ►diabetesjournals.org [PDF] AWK Tso, A Xu, PC Sham, N Wat, Y Wang, … - Diabetes Care, 2007 - Am Diabetes Assoc Annette WK Tso, MD1*, Aimin Xu, PhD1,2*, Pak C Sham, MD3, Nelson MS Wat, MD1, Yu
Wang, PhD3, Carol HY Fong, BSc1, Bernard MY Cheung, MD1, 2, Edward D Janus,
PhD4, Karen SL Lam, MD1, 2. ... 1Department of Medicine, 2Research Centre ... Cited by 24 - Related articles - BL Direct - All 4 versions
M Furuhashi, R Fucho, CZ Görgün, G Tuncman … - The Journal of Clinical Investigation, 2008 - pubmedcentral.nih.gov Adipose tissue inflammation is a characteristic of obesity. However, the
mechanisms that regulate this inflammatory response and link adipose
inflammation to systemic metabolic consequences are not fully understood. ... Cited by 22 - Related articles - All 7 versions
- ►eje-online.org M Mohlig, MO Weickert, E Ghadamgadai, A … - European Journal of Endocrinology, 2007 - EFES Results: A-FABP correlated with body mass index (BMI; R = 0.694, P < 0.001),
dual-energy X-ray-absorptiometry (DEXA) fat mass (R = 0.729, P < 0.001), DEXA
lean body mass (R = 0.399, P = 0.001), HOMA %S (R = –0.435, P < 0.001), ... Cited by 9 - Related articles - BL Direct - All 8 versions
E Erbay, H Cao, GS Hotamisligil - Current Atherosclerosis Reports, 2007 - Springer The link between inflammation and the development of insulin resistance, type 2
diabetes, and atherosclerosis has been uncovered in the past decade. Although
the molecular mechanisms underlying the co-occurrence of these metabolic ... Cited by 8 - Related articles - BL Direct - All 2 versions
AC Carpentier - Diabetes and Metabolism, 2008 - Elsevier Insulin resistance (IR) and impaired glucose-stimulated insulin secretion (GSIS)
are the two primary pathophysiological abnormalities leading to the development
of type 2 diabetes (T2D). Over the past two decades, a large body of work ... Cited by 8 - Related articles - BL Direct - All 2 versions
L Zhang, G Perdomo, DH Kim, S Qu, S … - Metabolism: clinical and experimental, 2008 - pubmedcentral.nih.gov High fructose consumption is associated with the development of fatty liver and
dyslipidemia with poorly understood mechanisms. We employed a MALDI-based
proteomics approach to define the molecular events that link high fructose ... Cited by 3 - Related articles - All 21 versions
KL Milner, D van der Poorten, A Xu, E … - Hepatology, 2009 - interscience.wiley.com A number of circulating cytokines are increased with obesity and may combine
with the influence of visceral fat to generate insulin resistance, inflammation
and fibrosis in non alcoholic fatty liver disease (NAFLD). Little ... Cited by 3 - Related articles - All 2 versions
