- ►diabetesjournals.org D Johnson, RM Shepherd, D Gill, T Gorman, … - Diabetes, 2007 - Am Diabetes Assoc Because glucokinase is a metabolic sensor involved in the regulated release of
insulin, we have investigated the acute actions of novel glucokinase activator
compound 50 (GKA50) on islet function. Insulin secretion was determined by ... Cited by 15 - Related articles - BL Direct - All 6 versions
MCT Fyfe, JR White, A Taylor, R Chatfield, E … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis We evaluated the insulinotropic and anti-
hyperglycaemic actions of glucokinase activators (GKAs), especially through
acute and subchronic studies in rodent diabetes models with (2R)-2-(4- ... Cited by 12 - Related articles - BL Direct - All 5 versions
- ►yale.edu [PDF] BE Levin, TC Becker, J Eiki, BB Zhang, AA … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—The counterregulatory response to insulin-induced hypoglycemia is
mediated by the ventromedial hypothalamus (VMH), which contains specialized
glucosensing neurons, many of which use glucokinase (GK) as the ... Cited by 7 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org C Arden, A Trainer, N de la Iglesia, KT … - Diabetes, 2007 - Am Diabetes Assoc Mutations in the glucokinase (GK) gene cause defects in blood glucose
homeostasis. In some cases (V62M and G72R), the phenotype cannot be explained by
altered enzyme kinetics or protein instability. We used transient and ... Cited by 7 - Related articles - BL Direct - All 4 versions
- ►jhc.org RL Sorenson, LE Stout, TC Brelje, TL Jetton, … - Journal of Histochemistry and Cytochemistry, 2007 - Histochemical Soc PITUITARY HORMONES exert extensive and profound influences on fuel homeostasis,
energy metabolism, growth, and reproduction of the organism. The regulation of
synthesis and secretion of these hormones is widely accepted to be ... Cited by 7 - Related articles - BL Direct - All 5 versions
- ►jbc.org MF Pino, KA Kim, KD Shelton, J Lindner, S … - Journal of Biological Chemistry, 2007 - ASBMB To better understand how glucokinase (GK) missense mutations associated with
human glycemic diseases perturb glucose homeostasis, we generated and
characterized mice with either an activating (A456V) or inactivating ... Cited by 6 - Related articles - All 7 versions
- ►jhc.org C Crane, N Akhter, BW Johnson, M … - Journal of Histochemistry and Cytochemistry, 2007 - Histochemical Soc LEPTIN IS A PRODUCT of the Ob gene that regulates satiety as well as energy
expenditure (Rowland et al. 1996 Go ). Its presence was initially discovered in
adipose tissue (Zhang et al. 1994 Go ), and it was first thought to be an ... Cited by 4 - Related articles - BL Direct - All 5 versions
T Gorman, DC Hope, R Brownlie, A Yu, D Gill … - Diabetes, Obesity and Metabolism, 2008 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 4 - Related articles - All 3 versions
BJ Bradford, MS Allen - Domestic Animal Endocrinology, 2008 - Elsevier The reported effects of feeding on growth hormone (GH) secretion in ruminants
have been inconsistent, and are likely influenced by energy status of animals.
High-producing dairy cows in early lactation and late lactation were used ... Cited by 3 - Related articles - All 4 versions