R Franco, OJ Schoneveld, A Pappa, MI … - Archives Of Physiology And Biochemistry, 2007 - informahealthcare.com Reduced glutathione (L-γ-glutamyl-L-cysteinyl-glycine, GSH) is the prevalent
low-molecular-weight thiol in mammalian cells. It is formed in a two-step
enzymatic process including, first, the formation of γ-glutamylcysteine ... Cited by 35 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org VR Drel, N Mashtalir, O Ilnytska, J Shin, F Li … - Diabetes, 2006 - Am Diabetes Assoc Whereas functional, metabolic, neurotrophic, and morphological abnormalities of
peripheral diabetic neuropathy (PDN) have been extensively explored in
streptozotocin-induced diabetic rats and mice (models of type 1 diabetes), ... Cited by 31 - Related articles - BL Direct - All 7 versions
PJ Oates - Current drug targets, 2008 - ingentaconnect.com Abstract: Aldose reductase (AR) enzymatically transforms cytosolic glucose into
sorbitol, a molecule that poorly pene- trates cell membranes and is sometimes
slowly metabolized. Hyperglycemia can cause intracellular accumulation of ... Cited by 26 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org C Toth, LL Rong, C Yang, J Martinez, F Song … - Diabetes, 2008 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS— Structural indexes of neuropathy were addressed
with serial (1, 3, 5, and 9 months of experimental diabetes)
electrophysiological and quantitative morphometric analysis of dorsal root ... Cited by 24 - Related articles - BL Direct - All 8 versions
- ►shouxi.net IG Obrosova, O Ilnytska, VV Lyzogubov, IA … - Diabetes, 2007 - Am Diabetes Assoc RESULTS—HFD-fed mice developed obesity, increased plasma FFA and insulin
concentrations, and impaired glucose tolerance. They also had motor and sensory
nerve conduction deficits, tactile allodynia, and thermal hypoalgesia in ... Cited by 20 - Related articles - BL Direct - All 6 versions
- ►academia.edu [PDF] I Vareniuk, IA Pavlov, VR Drel, VV Lyzogubov, … - Experimental Neurology, 2007 - Elsevier Nitrosative stress contributes to nerve conduction slowing, thermal hypoalgesia,
and impaired nitrergic innervation in animal models of Type 1 diabetes. The role
for reactive nitrogen species in Type 2 diabetes-associated neuropathy ... Cited by 19 - Related articles - All 5 versions
AP Kellogg, TD Wiggin, DD Larkin, JM Hayes, … - Diabetes, 2007 - Am Diabetes Assoc RESULTS—Under normal conditions, there were no differences in blood glucose,
peripheral nerve electrophysiology, markers of oxidative stress, inflammation,
and IENF density between COX-2 +/+ and COX-2 −/− mice. After 6 months, ... Cited by 14 - Related articles - BL Direct - All 4 versions
VR Drel, P Pacher, I Vareniuk, I Pavlov, O … - European journal of pharmacology, 2007 - pubmedcentral.nih.gov Whereas an important role of free radicals and oxidants in peripheral diabetic
neuropathy is well established, the contribution of nitrosative stress and, in
particular, of the highly reactive oxidant peroxynitrite, has not been ... Cited by 13 - Related articles - All 6 versions
Y Ido - Antioxidants & Redox Signaling, 2007 - liebertonline.com C HEMICAL REACTIONS involving movement of electrons are called redox reactions
(reduction and oxidation). This review will describe characteristics of redox
abnormali- ties observed in diabetes. Diabetes affects a number of tissues ... Cited by 11 - Related articles - BL Direct - All 5 versions
C Figueroa-Romero, M Sadidi, EL Feldman - Reviews in Endocrine & Metabolic Disorders, 2008 - Springer Abstract Diabetic neuropathy is the most common com- plication of diabetes,
affecting 50% of diabetic patients. Currently, the only treatment for diabetic
neuropathy is glucose control and careful foot care. In this review, we ... Cited by 11 - Related articles - All 2 versions
