E Suviolahti, HE Lilja, P Pajukanta - Annals of Medicine, 2006 - informahealthcare.com Familial combined hyperlipidemia (FCHL) constitutes a substantial risk factor
for atherosclerosis since it is observed in about 20% of coronary heart disease
(CHD) patients under 60 years. FCHL, characterized by elevated levels of ... Cited by 22 - Related articles - BL Direct - All 7 versions
- ►ahajournals.org R Mar-Heyming, M Miyazaki, D Weissglas- … - Arteriosclerosis, thrombosis, and vascular biology, 2008 - Am Heart Assoc Methods and Results— The fatty acid desaturation index was measured in 400
individuals from 18 extended FCHL pedigrees. FCHL-affected individuals exhibited
increased SCD1 activity when compared to unrelated controls (P<0.0001). The ... Cited by 8 - Related articles - All 6 versions
- ►nih.gov JC Lee, D Weissglas-Volkov, M Kyttälä, Z … - The American Journal of Human Genetics, 2008 - Elsevier Low serum HDL-cholesterol (HDL-C) is a major risk factor for coronary artery
disease. We performed targeted genotyping of a 12.4 Mb linked region on 16q to
test for association with low HDL-C by using a regional-tag SNP strategy. ... Cited by 6 - Related articles - All 6 versions
L Love-Gregory, MA Permutt - Current Opinion in Clinical Nutrition & Metabolic Care, 2007 - journals.lww.com Purpose of review: Variants in the hepatocyte nuclear factor 4α (HNF4A) gene
play a role in the development of diabetes mellitus. Although genetic variation
in and around HNF4A regulatory regions has received considerable attention, ... Cited by 6 - Related articles - BL Direct - All 5 versions
- Free from Publisher G Jimenez-Sanchez, I Silva-Zolezzi, A … - Genome Research, 2008 - pixfunlobdot.59.to Mexico faces important demographic and epidemiological transitions with
significant implications to patterns of disease, disability, and death. On the
one hand, there are problems of underdevelopment and, on the other, the ... Cited by 7 - Related articles - All 11 versions
LW Harries - Expert Review of Endocrinology and Metabolism, 2006 - ingentaconnect.com Variation in mRNA processing has the capacity to exert fine control over gene
expression in most cell types. The hepatic nuclear factor genes, like
approximately 74% of the genome, produce multiple transcripts. Hepatic ... Cited by 3 - Related articles - All 3 versions
JP Schanstra, M Bachvarova, E Neau, JL … - Kidney International, 2007 - nature.com Angiotensin-converting enzyme inhibitors are the most efficient pharmacologic
agents to delay the development of end-stage renal disease (ESRD). This is a
multipharmacologic approach that inhibits angiotensin II formation while ... Cited by 3 - Related articles - BL Direct - All 3 versions
AS Wierzbicki, CA Graham, IS Young, DP … - Current Vascular Pharmacology, 2008 - ingentaconnect.com Abstract: Familial combined hyperlipidaemia (FCH) was identified in early
genetic studies of populations as a dominant condition associated with mixed
hyperlipidaemia and early onset coronary heart disease. Later studies ... Cited by 3 - Related articles - BL Direct - All 2 versions
- ►ahajournals.org [PDF] F Karpe, L Hodson - Arteriosclerosis, Thrombosis, and Vascular Biology, 2008 - Am Heart Assoc Accordingly, assessment of the surrogate marker for SCD1 activity in whole
plasma may generate data that are very difficult to interpret when groups with
different triglyceride concentrations are compared, and, in fact, ... Cited by 2 - Related articles - All 3 versions
O Nyunt, JY Wu, IN McGown, M Harris, T …, 2009 - pubmedcentral.nih.gov Maturity Onset Diabetes of Young (MODY) is a monogenic and autosomal dominant
form of diabetes mellitus with onset of the disease often before 25 years of
age. It is due to dysfunction of pancreatic ß cells characterised by non- ... Cited by 1 - Related articles - All 5 versions
