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Scholar Results 1 - 10 of about 24 citing Bowden: Coincident linkage of type 2 diabetes, metabolic syndrome, and measures of cardiovascular.... (0.08 sec) 

Do glucose and lipids exert independent effects on atherosclerotic lesion initiation or …

- ahajournals.org
JE Kanter, F Johansson, RC LeBoeuf, KE … - Circulation research, 2007 - Am Heart Assoc
It is becoming increasingly clear that suboptimal blood glucose control results
in adverse effects on large blood vessels, thereby accelerating atherosclerosis
and cardiovascular disease, manifested as myocardial infarction, stroke, ...
Cited by 32 - Related articles - All 8 versions

Peakwide mapping on chromosome 3q13 identifies the kalirin gene as a novel candidate …

- nih.gov
L Wang, ER Hauser, SH Shah, MA Pericak- … - The American Journal of Human Genetics, 2007 - Elsevier
A susceptibility locus for coronary artery disease (CAD) has been mapped to
chromosome 3q13-21 in a linkage study of early-onset CAD. We completed an
association-mapping study across the 1-LOD–unit-down supporting interval, ...
Cited by 28 - Related articles - BL Direct - All 7 versions

GATA2 is associated with familial early-onset coronary artery disease


JJ Connelly, T Wang, JE Cox, C Haynes, L … - PLoS Genet, 2006 - genetics.plosjournals.org
The transcription factor GATA2 plays an essential role in the establishment and
maintenance of adult hematopoiesis. It is expressed in hematopoietic stem cells,
as well as the cells that make up the aortic vasculature, namely aortic ...
Cited by 28 - Related articles - Cached - All 10 versions

The genetic landscape of type 2 diabetes in mice

- endojournals.org
SM Clee, AD Attie - Endocrine reviews, 2007 - Endocrine Soc
Inbred mouse strains provide genetic diversity comparable to that of the human
population. Like humans, mice have a wide range of diabetes-related phenotypes.
The inbred mouse strains differ in the response of their critical ...
Cited by 28 - Related articles - BL Direct - All 4 versions

Association of NOS1AP genetic variants with QT interval duration in families from the …


AB Lehtinen, C Newton-Cheh, JT Ziegler, CD … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—In European Americans, rs10494366 minor homozygotes had a
9.3-ms-longer QT interval compared with major homozygotes (P = 5.7 × 10 −5 );
rs10918594 minor homozygotes had a 12.5-ms-longer QT interval compared with ...
Cited by 24 - Related articles - BL Direct - All 4 versions

Psoriasis and metabolic disease: epidemiology and pathophysiology

- upenn.edu [PDF] 
RS Azfar, JM Gelfand - Current Opinion in Rheumatology, 2008 - journals.lww.com
Recent findings: Psoriasis is associated with metabolic syndrome, and its
components, such as obesity, diabetes, and hypertension. Obesity has been shown
to be an independent risk factor for the development of psoriasis, and is ...
Cited by 11 - Related articles - All 12 versions

Polymorphisms of the tumor suppressor gene LSAMP are associated with left main coronary …


L Wang, ER Hauser, SH Shah, D Seo, P … - Annals of human genetics, 2008 - pubmedcentral.nih.gov
Previous association mapping on chromosome 3q13-21 detected evidence for
association at the limbic system-associated membrane protein (LSAMP) gene in
individuals with late-onset coronary artery disease (CAD). LSAMP has never ...
Cited by 5 - Related articles - All 5 versions

Genetics of metabolic syndrome


T Joy, P Lahiry, RL Pollex, RA Hegele - Current Diabetes Reports, 2008 - Springer
Metabolic syndrome (MetS) is a common phenotype, affecting about 24% of the US
population. It is associated with an increased risk for type 2 diabetes and
cardiovas- cular disease. Although there is no universally accepted ...
Cited by 6 - Related articles - BL Direct - All 2 versions

Interpreting analyses of continuous covariates in affected sibling pair linkage studies


S Schmidt, X Qin, MA Schmidt, ER Martin, ER … - Genetic Epidemiology, 2007 - interscience.wiley.com
Datasets collected for linkage analyses of complex human diseases often include
a number of clinical or environmental covariates. In this study, we evaluated
the performance of three linkage analysis methods when the relationship ...
Cited by 4 - Related articles - BL Direct - All 2 versions

Neuropeptide Y gene polymorphisms confer risk of early-onset atherosclerosis


SH Shah, NJ Freedman, L Zhang, DR Crosslin … - PLoS Genetics, 2009 - pubmedcentral.nih.gov
Neuropeptide Y (NPY) is a strong candidate gene for coronary artery disease
(CAD). We have previously identified genetic linkage to familial CAD in the
genomic region of NPY. We performed follow-up genetic, biostatistical, and ...
Cited by 4 - Related articles - All 6 versions


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