- ►physiology.org JJ Holst - Physiological reviews, 2007 - Am Physiological Soc Glucagon-like peptide 1 (GLP-1) is a 30-amino acid peptide hormone produced in the intestinal
epithelial endocrine L-cells by differential processing of proglucagon, the gene which is expressed
in these cells. The current knowledge regarding regulation of proglucagon gene ... Cited by 119 - Related articles - BL Direct - All 5 versions
- ►physiology.org PL McClean, N Irwin, RS Cassidy, JJ Holst … - American Journal of …, 2007 - Am Physiological Soc The gut hormone gastric inhibitory polypeptide (GIP) plays a key role in glucose homeostasis
and lipid metabolism. This study investigated the effects of administration of a stable and specific
GIP receptor antagonist, (Pro 3 )GIP, in mice previously fed a high-fat diet for 160 days to ... Cited by 27 - Related articles - BL Direct - All 3 versions
N Irwin, PL McClean, FPM O'Harte, VA Gault, P Harriott, … - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Ablation of gastric inhibitory polypeptide (GIP) receptor action is reported
to protect against obesity and associated metabolic abnormalities. The aim of this study was
to use prediabetic ob/ob mice to examine whether 60 days of chemical GIP receptor ... Cited by 26 - Related articles - BL Direct - All 5 versions
- ►eje.org MJF Bult, T van Dalen, AF Muller - European Journal of Endocrinology, 2008 - eje.org More than half of the European population are overweight (body mass index (BMI) >25 and
<30 kg/m 2 ) and up to 30% are obese (BMI 30 kg/m 2 ). Being overweight and obesity are becoming
endemic, particularly because of increasing nourishment and a decrease in physical ... Cited by 28 - Related articles - BL Direct - All 7 versions
- ►qub.ac.uk [PDF] BD Green, PR Flatt - Best Practice & Research Clinical Endocrinology & …, 2007 - Elsevier The incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic
polypeptide (GIP) are physiological gut peptides with insulin-releasing and extrapancreatic glucoregulatory
actions. Incretin analogues/mimetics activate GLP-1 or GIP receptors whilst avoiding ... Cited by 29 - Related articles - All 17 versions
J Korner, M Bessler, W Inabnet, C Taveras, JJ … - Surgery for Obesity and …, 2007 - Elsevier The fasting glucose level was similar between the 2 surgery groups; however, the fasting insulin
concentrations were greater in the BND (10.0 μU/mL) than in the RYGB (6.2 μU/mL; P <0.05)
group. The glucose level at 60 minutes was significantly lower in the RYGB group (70 ... Cited by 25 - Related articles - All 7 versions
BA Whitson, DB Leslie, TA Kellogg, MA Maddaus, … - Journal of Surgical …, 2007 - Elsevier Mean patient age was 42 ± 11 years, and the mean preoperative body mass index was 50 ±
6 kg/m 2 . At 6 months mean BMI fell to 33 ± 5 kg/m 2 (P < 0.0001), and there were no differences
between diabetics and nondiabetics with respect to amount of weight loss. In ... Cited by 20 - Related articles - All 16 versions
- ►sicob.org [PDF] N Scopinaro, F Papadia, G Marinari, G Camerini, G … - Obesity Surgery, 2007 - Springer Background: Bariatric operations are the most power- ful means of curing type 2 diabetes mellitus
(T2D) and the other major components of the metabolic syn- drome. Despite the very frequent
occurrence of meta- bolic disturbances in patients with BMI from 30 to 35, there is a ... Cited by 18 - Related articles - BL Direct - All 4 versions
VA Gault, PL McClean, RS Cassidy, N Irwin, PR Flatt - Diabetologia, 2007 - Springer Abstract Aims/hypothesis Gastric inhibitory polypeptide (GIP) re- ceptor antagonism with (Pro
3 )GIP improves glucose toler- ance and ameliorates insulin resistance and abnormalities of
islet structure/function in ob/ob mice. This study examined the ability of (Pro 3 )GIP to ... Cited by 16 - Related articles - BL Direct - All 4 versions
PR Flatt - Diabetes & Vascular Disease Research, 2007 - dvr.sagepub.com Abstract R oux-en-Y bypass surgery is increasingly used for treatment of gross obesity due to
the general inabil- ity of lifestyle change and existing drug treatments to counter the obesity
epidemic. This common form of bariatric surgery involves bypass of the small intestine ... Cited by 13 - Related articles - BL Direct - All 6 versions
