- ►asnjournals.org M Ye, J Wysocki, J William, MJ Soler, I Cokic, … - Journal of the American Society of Nephrology, 2006 - Am Soc Nephrol Angiotensin-converting enzyme 2 (ACE2) expression has been shown to be altered
in renal tubules from diabetic mice. This study examined the localization of ACE
and ACE2 within the glomerulus of kidneys from control (db/m) and diabetic ... Cited by 59 - Related articles - BL Direct - All 6 versions
- ►oxfordjournals.org JC Zhong, XY Yu, Y Huang, LM Yung, CW Lau … - Cardiovascular research, 2007 - cardiovascres.oxfordjournals.org Results: There is depressed expression of APJ, enhanced contractile response to
Ang II, and reduced relaxation response to acetylcholine in aortas from db/db
mice. Apelin treatment strikingly reversed the altered aortic vascular ... Cited by 36 - Related articles - All 7 versions
- ►amjpathol.org DW Wong, GY Oudit, H Reich, Z Kassiri, J … - American Journal of Pathology, 2007 - ASIP Activation of the renin-angiotensin system (RAS) and the generation of
angiotensin (Ang) II play an important role in the pathogenesis of diabetic
nephropathy and blockade of the RAS in both experimental and clinical ... Cited by 34 - Related articles - BL Direct - All 8 versions
I Hamming, ME Cooper, BL Haagmans, NM … - Journal of Pathology, 2007 - dissertations.ub.rug.nl The renin-angiotensin-aldosterone system (RAAS) is a key regulator of systemic
blood pressure and renal function and a key player in renal and cardiovascular
disease. However, its (patho)physiological roles and its architecture are ... Cited by 33 - Related articles - View as HTML - BL Direct - All 5 versions
- ►physiology.org MF Doobay, LS Talman, TD Obr, X Tian, RL … - … Journal of Physiology- Regulatory, Integrative and …, 2007 - Am Physiological Soc Angiotensin-converting enzyme 2 (ACE2) is a newly discovered carboxy-peptidase
responsible for the formation of vasodilatory peptides such as
angiotensin-(1–7). We hypothesized that ACE2 is part of the brain renin- ... Cited by 28 - Related articles - BL Direct - All 6 versions
RAS Santos, AJ Ferreira - Current Opinion in Nephrology and Hypertension, 2007 - journals.lww.com Purpose of review In this review we will focus on the recent findings related to
angiotensin-(1–7) as an angiotensin II counter-regulatory peptide within the
renin–angiotensin system. Recent findings The identification of the ... Cited by 26 - Related articles - BL Direct - All 7 versions
MJ Soler, J Wysocki, M Ye, J Lloveras, Y … - Kidney International, 2007 - nature.com Angiotensin converting enzyme 2 (ACE2) is localized to the glomerular epithelial
cells. Since ACE2 promotes the degradation of angiotensin II, a decrease in ACE2
activity could lead to the development of glomerular injury. We gave a ... Cited by 28 - Related articles - BL Direct - All 3 versions
- ►physoc.org RAS Santos, AJ Ferreira, AC Simões e Silva - Experimental Physiology, 2008 - Physiological Soc In the past few years, the classical concept of the renin–angiotensin system
(RAS) has experienced substantial conceptual changes. The identification of: the
renin/prorenin receptor; the angiotensin-converting enzyme homologue, ACE2, ... Cited by 27 - Related articles - BL Direct - All 9 versions
MK Raizada, AJ Ferreira - Journal of cardiovascular pharmacology, 2007 - journals.lww.com The discovery of angiotensin-converting enzyme 2 (ACE2) in 2000 is an important
event in the renin-angiotensin system (RAS) story. This enzyme, an homolog of
ACE, hydrolyzes angiotensin (Ang) I to produce Ang-(1-9), which is ... Cited by 24 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org MC Chappell - Hypertension, 2007 - Am Heart Assoc From the initial description of renin activity over a century ago, the ongoing
study of the renin-angiotensin (Ang)-aldosterone system (RAAS) continues to
yield unexpected findings that redefine the functional nature of this ... Cited by 24 - Related articles - All 8 versions
