- ►nih.gov SR Hubbard, WT Miller - Current opinion in cell biology, 2007 - Elsevier Tyrosine phosphorylation is a highly regulated post-translational modification that is essential
for inter- and intracellular communication in metazoans. The enzymes that catalyze phosphoryl
transfer to tyrosine residues in protein substrates, using ATP as a phosphate donor, are ... Cited by 50 - Related articles - All 6 versions
- ►cell.com L Bai, Y Wang, J Fan, Y Chen, W Ji, A Qu, P Xu, DE … - Cell Metabolism, 2007 - Elsevier Insulin-stimulated GLUT4 translocation is central to glucose homeostasis. Functional assays
to distinguish individual steps in the GLUT4 translocation process are lacking, thus limiting progress
toward elucidation of the underlying molecular mechanism. Here we have developed a ... Cited by 48 - Related articles - All 12 versions
MO Collins, L Yu, JS Choudhary - PROTEOMICS-Clinical Applications - interscience.wiley.com Phosphorylation, the most intensively studied and common PTM on proteins, is a complex biological
phenomenon. Its complexity manifests itself in the large numbers of proteins that attach it, remove
it and recognise it as a protein code. Since the first report of protein phosphorylation on ... Cited by 46 - Related articles - BL Direct - All 4 versions
- ►pnas.org M Krüger, I Kratchmarova, B Blagoev, YH … - Proceedings of the …, 2008 - National Acad Sciences The insulin signaling pathway is of pivotal importance in metabolic diseases, such as
diabetes, and in cellular processes, such as aging. Insulin activates a tyrosine phosphorylation
cascade that branches to create a complex network affecting multiple biological ... Cited by 37 - Related articles - BL Direct - All 6 versions
SS Jensen, MR Larsen - Rapid Communications in Mass …, 2007 - interscience.wiley.com The complete characterization of phosphorylated proteins requires an efficient procedure for
the enrichment of phosphopeptides from amongst a complicated peptide mixture. The sensitivity
of the traditional immobilized metal affinity chromatography (IMAC) approach is severely ... Cited by 28 - Related articles - BL Direct - All 3 versions
- ►jlr.org PF Pilch, RP Souto, L Liu, MP Jedrychowski, EA … - The Journal of Lipid …, 2007 - ASBMB It has been known for decades that the adipocyte cell surface is particularly rich in small invaginations
we now know to be caveolae. These structures are common to many cell types but are not
ubiquitous. They have generated considerable curiosity, as manifested by the numerous ... Cited by 20 - Related articles - All 3 versions
- ►angiogenesis.nl [PDF] MA Cabrita, G Christofori - Angiogenesis, 2008 - Springer Abstract Angiogenesis relies on endothelial cells prop- erly processing signals from growth factors
provided in both an autocrine and a paracrine manner. These mitogens bind to their cognate
receptor tyrosine kinases (RTKs) on the cell surface, thereby activating a myriad of ... Cited by 14 - Related articles - BL Direct - All 4 versions
- ►wisc.edu [PDF] R Bose, MA Holbert, KA Pickin, PA Cole - Current opinion in structural biology, 2006 - Elsevier Protein tyrosine kinases (PTKs) are enzymes that catalyze the phosphorylation of tyrosyl
residues. They are important in physiological and pathophysiological processes. Protein substrates
of PTKs are often difficult to discern, but recently reported methods have helped to identify ... Cited by 12 - Related articles - All 5 versions
A Nita-Lazar, H Saito-Benz, FM White - Proteomics, 2008 - assets0.pubget.com Protein phosphorylation-mediated signaling networks regulate much of the cellular response
to external stimuli, and dysregulation in these networks has been linked to multiple disease
states. Significant advancements have been made over the past decade to enable the ... Cited by 13 - Related articles - View as HTML - All 4 versions
