- ►endojournals.org R Muniyappa, M Montagnani, KK Koh, MJ … - Endocrine reviews, 2007 - Endocrine Soc Insulin has important vascular actions to stimulate production of nitric oxide
from endothelium. This leads to capillary recruitment, vasodilation, increased
blood flow, and subsequent augmentation of glucose disposal in classical ... Cited by 97 - Related articles - BL Direct - All 5 versions
- ►physiology.org SA Cooper, A Whaley-Connell, J Habibi, Y Wei … - American Journal of Physiology- Heart and Circulatory …, 2007 - Am Physiological Soc Hypertension commonly occurs in conjunction with insulin resistance and other
components of the cardiometabolic syndrome. Insulin resistance plays a
significant role in the relationship between hypertension, Type 2 diabetes ... Cited by 40 - Related articles - BL Direct - All 4 versions
- ►jbc.org S Crunkhorn, F Dearie, C Mantzoros, H Gami, … - Journal of Biological Chemistry, 2007 - ASBMB Peroxisome proliferator activator receptor- coactivator 1 (PGC-1) is a major
candidate gene for diabetes-related metabolic phenotypes, contributing to
decreased expression of nuclear-encoded mitochondrial genes in muscle and ... Cited by 28 - Related articles - All 3 versions
- ►jbc.org HY Liu, QF Collins, Y Xiong, F Moukdar, EG … - Journal of Biological Chemistry, 2007 - ASBMB Free fatty acid (FFA) is believed to be a major environmental factor linking
obesity to Type II diabetes. We have recently reported that FFA can induce
gluconeogenesis in hepatocytes through p38 mitogen-activated protein kinase ... Cited by 28 - Related articles - All 6 versions
- ►ahajournals.org P Song, Y Wu, J Xu, Z Xie, Y Dong, M Zhang, … - Circulation, 2007 - Am Heart Assoc Methods and Results— Exposure of cultured human umbilical vein endothelial
cells to either peroxynitrite (ONOO – ) or high glucose significantly
inhibited both basal and insulin-stimulated Akt phosphorylation at Ser473 ... Cited by 23 - Related articles - All 6 versions
LZ Yi, J He, YZ Liang, DL Yuan, FT Chau - FEBS letters, 2006 - Elsevier Metabolic profiling has increasingly been used as a probe in disease diagnosis
and pharmacological analysis. Herein, plasma fatty acid metabolic profiling
including non-esterified fatty acid (NEFA) and esterified fatty acid (EFA) ... Cited by 18 - Related articles - All 11 versions
- ►sherbornegibbs.com [PDF] RM Cubbon, A Rajwani, SB Wheatcroft - Diabetes & Vascular Disease Research, 2007 - dvr.sagepub.com Abstract T he structural and functional integrity of the vascular endothelium
plays a critical role in vascular homeo- stasis. Insulin resistance, an
important risk factor for cardiovascular disease, is thought to promote ... Cited by 17 - Related articles - BL Direct - All 8 versions
- Free from Publisher M Dysfunction, CDA Stehouwer - Physiology, 2007 - sochob.cl Evidence from several studies indicates that obesity impairs microvascular
function in several ways. First, impairments of endothelial function of
different microvascular structures have been demonstrated in obesity. Obese ... Cited by 13 - Related articles - View as HTML - BL Direct - All 6 versions
- ►nursing2008.com R Muniyappa, MJ Quon - Current Opinion in Clinical Nutrition & Metabolic Care, 2007 - journals.lww.com Purpose of review: Vasodilator actions of insulin are mediated by
phosphatidylinositol 3-kinase dependent insulin signaling pathways in
endothelium, which stimulate production of nitric oxide. Insulin-stimulated ... Cited by 13 - Related articles - BL Direct - All 6 versions
H Wang, LA Knaub, DR Jensen, D Young Jung … - Diabetes, 2009 - Am Diabetes Assoc RESULTS—Nine-week-old SMLPL −/− mice showed no differences in body weight,
fat mass, or whole-body insulin sensitivity, but older SMLPL −/− mice had
greater weight gain and whole-body insulin resistance. High-fat diet ... Cited by 12 - Related articles - All 5 versions
