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Scholar Results 1 - 10 of about 17 citing Kim: Insulin regulation of skeletal muscle PDK4 mRNA expression is impaired in acute insulin-resi.... (0.19 sec) 

Resveratrol improves mitochondrial function and protects against metabolic disease by …

- rayandterry.com [PDF] 
M Lagouge, C Argmann, Z Gerhart-Hines, H … - Cell, 2006 - Elsevier
Diminished mitochondrial oxidative phosphorylation and aerobic capacity are
associated with reduced longevity. We tested whether resveratrol (RSV), which is
known to extend lifespan, impacts mitochondrial function and metabolic ...
Cited by 416 - Related articles - All 20 versions

[PDF] Advances in molecular biology of hibernation in mammals


MT Andrews - Bioessays, 2007 - mnf.uni-greifswald.de
Summary Mammalian hibernation is characterized by profound reductions in
metabolism, oxygen consumption and heart rate. As a result, the animal enters a
state of suspended animation where core body temperatures can plummet as ...
Cited by 12 - Related articles - View as HTML - BL Direct - All 4 versions

Effects of iron loading on muscle: genome-wide mRNA expression profiling in the mouse


A Rodriguez, M Hilvo, L Kytömäki, RE Fleming … - BMC genomics, 2007 - biomedcentral.com
Hereditary hemochromatosis (HH) encompasses genetic disorders of iron overload
characterized by deficient expression or function of the iron-regulatory hormone
hepcidin. Mutations in 5 genes have been linked to this disease: HFE, TFR2 ( ...
Cited by 9 - Related articles - Cached - All 6 versions

Control of muscle mitochondria by insulin entails activation of Akt2-mtNOS pathway: …


P Finocchietto, F Barreyro, S Holod, J … - PLoS ONE, 2008 - pubmedcentral.nih.gov
We illustrate here that NO produced by translocated nNOS (mtNOS) is the
insulin-signaling molecule that controls mitochondrial oxygen utilization. We
evoke a hyperinsulinemic-normoglycemic non-invasive clamp by subcutaneously ...
Cited by 9 - Related articles - All 6 versions

Glucose infusion causes insulin resistance in skeletal muscle of rats without changes in …

- physiology.org
AJ Hoy, CR Bruce, A Cederberg, N Turner, … - American Journal of Physiology- Endocrinology And …, 2007 - Am Physiological Soc
Hyperglycemia is a defining feature of Type 1 and 2 diabetes. Hyperglycemia also
causes insulin resistance, and our group (Kraegen EW, Saha AK, Preston E, Wilks
D, Hoy AJ, Cooney GJ, Ruderman NB. Am J Physiol Endocrinol Metab Endocrinol ...
Cited by 8 - Related articles - BL Direct - All 3 versions

Elevated free fatty acids attenuate the insulin-induced suppression of PDK4 gene expression …

- endojournals.org
K Tsintzas, K Chokkalingam, K Jewell, L … - Journal of Clinical Endocrinology & Metabolism, 2007 - Endocrine Soc
Results: Glucose disposal was approximately 50% lower at the end of the clamp in
the LIPID compared with the CON trial (37.8 ± 4.4 and 79.6 ± 4.0 µmol/kg lean
mass·min, respectively; P < 0.01). In the LIPID trial, muscle long-chain ...
Cited by 6 - Related articles - BL Direct - All 3 versions

A potential role for Akt/FOXO signalling in both protein loss and the impairment of muscle …


H Crossland, D Constantin-Teodosiu, SM … - The Journal of Physiology, 2008 - Physiological Soc
Sepsis causes muscle atrophy and insulin resistance, but the underlying
mechanisms are unclear. Therefore, the present study examined the effects of
lipopolysaccharide (LPS)-induced endotoxaemia on the expression of Akt, ...
Cited by 6 - Related articles - All 9 versions

Insulin action and signalling in fat and muscle from dexamethasone-treated rats


J Burén, YC Lai, M Lundgren, JW Eriksson, J … - Archives of Biochemistry and Biophysics, 2008 - Elsevier
Glucocorticoids initiate whole body insulin resistance and the aim of the
present study was to investigate effects of dexamethasone on protein expression
and insulin signalling in muscle and fat tissue. Rats were injected with ...
Cited by 4 - Related articles - All 2 versions

Crosstalk between the AMP-activated kinase and insulin signaling pathways rescues murine …

- reproduction-online.org
E Louden, MM Chi, KH Moley - Reproduction, 2008 - Soc Reprod Fertility
Maternal insulin resistance results in poor pregnancy outcomes. In vivo and in
vitro exposure of the murine blastocyst to high insulin or IGF1 results in the
down-regulation of the IGF1 receptor (IGF1R). This in turn leads to ...
Cited by 3 - Related articles - All 5 versions

PPAR {delta} agonism inhibits skeletal muscle PDC activity, mitochondrial ATP production …


D Constantin-Teodosiu, DJ Baker, D … - The Journal of Physiology, 2009 - Physiological Soc
We have recently shown that PPAR agonism, used clinically to treat insulin
resistance, increases fat oxidation and up-regulates mitochondrial PDK4 mRNA and
protein expression in resting skeletal muscle. We hypothesized that PDK4 up- ...
Cited by 1 - Related articles - All 5 versions


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