- ►endojournals.org J Gromada, I Franklin, CB Wollheim - Endocrine reviews, 2007 - Endocrine Soc Glucagon, a hormone secreted from the -cells of the endocrine pancreas, is
critical for blood glucose homeostasis. It is the major counterpart to insulin
and is released during hypoglycemia to induce hepatic glucose output. The ... Cited by 60 - Related articles - BL Direct - All 4 versions
PE MacDonald, YZ De Marinis, R Ramracheya, … - PLoS Biol, 2007 - biology.plosjournals.org Glucagon, secreted from pancreatic islet α cells, stimulates gluconeogenesis
and liver glycogen breakdown. The mechanism regulating glucagon release is
debated, and variously attributed to neuronal control, paracrine control by ... Cited by 25 - Related articles - Cached - All 7 versions
E Vieira, A Salehi, E Gylfe - Diabetologia, 2007 - Springer Abstract Aims/hypothesis The mechanisms by which glucose regu- lates glucagon
release are poorly understood. The present study aimed to clarify the direct
effects of glucose on the glucagon-releasing alpha cells and those effects ... Cited by 23 - Related articles - BL Direct - All 4 versions
E Flodgren, B Olde, S Meidute-Abaraviciene, … - Biochemical and Biophysical Research …, 2007 - Elsevier The free fatty acid receptor, GPR40, has been coupled with insulin secretion via
its expression in pancreatic β-cells. However, the role of GPR40 in the release
of glucagon has not been studied and previous attempts to identify the ... Cited by 15 - Related articles - All 5 versions
SJ Bailey, MA Ravier, GA Rutter - Diabetes, 2007 - Am Diabetes Assoc The mechanism(s) by which glucose regulates glucagon secretion both acutely and
in the longer term remain unclear. Added to isolated mouse islets in the
presence of 0.5 mmol/l glucose, γ-aminobutyric acid (GABA) inhibited ... Cited by 9 - Related articles - BL Direct - All 7 versions
- ►endojournals.org F Xia, YM Leung, G Gaisano, X Gao, Y Chen, … - Endocrinology, 2007 - Endocrine Soc Pancreatic -cells secrete glucagon in response to low glucose to counter insulin
actions, thereby maintaining glucose homeostasis. The molecular basis of -cell
stimulus-secretion coupling has not been fully elucidated. We investigated ... Cited by 7 - Related articles - BL Direct - All 3 versions
- ►endojournals.org E Goncz, MZ Strowski, C Grotzinger, KW … - Endocrinology, 2008 - Endocrine Soc Orexin-A (OXA) regulates food intake and energy homeostasis. It increases
insulin secretion in vivo and in vitro, although controversial effects of OXA on
plasma glucagon are reported. We characterized the effects of OXA on ... Cited by 7 - Related articles - BL Direct - All 4 versions
- ►physiology.org P Bansal, Q Wang - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc Glucose homeostasis is regulated primarily by the opposing actions of insulin
and glucagon, hormones that are secreted by pancreatic islets from β-cells and
-cells, respectively. Insulin secretion is increased in response to ... Cited by 6 - Related articles - All 3 versions
- ►cell.com P Rorsman, SA Salehi, F Abdulkader, M … - Trends in Endocrinology & Metabolism, 2008 - Elsevier Glucagon, secreted by the α-cells of the pancreatic islets, is the most
important glucose-increasing hormone of the body. The precise regulation of
glucagon release remains incompletely defined but has been proposed to ... Cited by 4 - Related articles - All 5 versions
C Xiao… - Clinical science (London, England: 1979), 2007 - pubmedcentral.nih.gov Pancreatic bi-hormones insulin and glucagon are the Yin and Yang in the
regulation of glucose metabolism and homoeostasis. Insulin is synthesized
primarily by pancreatic β-cells and is released in response to an increase ... Cited by 3 - Related articles - BL Direct - All 9 versions
