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Scholar Results 1 - 10 of about 14 citing Saukkonen: Effects of recombinant human IGF-I/IGF-binding protein-3 complex on glucose and.... (0.17 sec) 

Involvement of insulin-like growth factor-I in the control of glucose homeostasis


DR Clemmons - Current opinion in pharmacology, 2006 - Elsevier
Insulin-like growth factor-I (IGF-I) has significant structural homology with
proinsulin. IGF-I binds to insulin receptors, stimulates insulin-like actions
and enhances insulin sensitivity. However, because circulating IGF-I is ...
Cited by 29 - Related articles - All 3 versions

The role of IGF-I and its binding proteins in the development of type 2 diabetes and …


VA Ezzat, ER Duncan, SB Wheatcroft, MT … - Diabetes, obesity & metabolism, 2008 - pt.wkhealth.com
Patients with insulin resistance and type 2 diabetes have an excessive risk of
cardiovascular disease (CVD); this increased risk is not fully explained by
traditional risk factors such as hypertension and dyslipidaemias. There is ...
Cited by 19 - Related articles - BL Direct - All 5 versions

A general and islet cell-enriched overexpression of IGF-I results in normal islet cell growth, …

- physiology.org
K Robertson, Y Lu, K De Jesus, B Li, Q Su, PK … - American Journal of Physiology- Endocrinology And …, 2008 - Am Physiological Soc
Insulin-like growth factor I (IGF-I) is normally produced from hepatocytes and
various other cells and tissues, including the pancreas, and is known to
stimulate islet cell replication in vitro, prevent Fas-mediated β-cell ...
Cited by 13 - Related articles - BL Direct - All 3 versions

Normalization of the IGF-IGFBP axis by sustained nightly insulinization in type 1 diabetes

- Free from Publisher
K Ekström, J Salemyr, I Zachrisson, C Carlsson … - Diabetes care, 2007 - Am Diabetes Assoc
RESULTS—Subnormal IGF-I SD scores on NPH (−1.8 ± 0.4) rapidly increased and
remained 54 ± 9% elevated (P < 0.001) after 12 weeks on glargine. A1C decreased
from 8.3 ± 0.6% to a nadir of 6.9 ± 0.3% (P = 0.002) at 6 weeks and ...
Cited by 7 - Related articles - BL Direct - All 5 versions

Mecasermin rinfabate: rhIGF-I/rhIGFBP-3 complex: iPLEX™


RM Williams, A McDonald, M O'Savage, DB … - Expert Opin. Drug Metab. Toxicol., 2008 - informahealthcare.com
Background: Mecasermin rinfabate (iPLEX ™ ), comprising rhIGF-I complexed to
rhIGFBP-3, was developed in an attempt to prolong the half-life of IGF-I and
potentially reduce side effects. It is administered as a once-daily ...
Cited by 7 - Related articles - BL Direct - All 6 versions

A novel method incorporating gene ontology information for unsupervised clustering and …


S Srivastava, L Zhang, R Jin, C Chan - PLoS ONE, 2008 - pubmedcentral.nih.gov
Here, we present a method that integrates gene ontology (GO) information and
expression data using Bayesian regression mixture models to perform unsupervised
clustering of the samples and identify physiologically relevant ...
Cited by 2 - Related articles - All 6 versions

Recombinant human insulin-like growth factor-1: a new cardiovascular disease treatment …


E Conti, MB Musumeci, GE Assenza, G Quarta … - Cardiovascular &# 38; Hematological Agents in …, 2008 - ingentaconnect.com
E. Conti 1,* , MB Musumeci 1 , G. Egidy Assenza 1 , G. Quarta 1 , C. Autore 1
and M. Volpe 1,2 ... 1 Cardiology Department, II Faculty of Medicine,
University “La Sapienza”, Rome, Italy; ... Abstract: The Insulin-like ...
Cited by 1 - Related articles - All 3 versions

A Pharmacokinetic and Dosing Study of Intravenous Insulin-Like Growth Factor-I and IGF- …

- critcaremed.org
… EVA ENGSTRÖM, LE FRIBERG, C CAMACHO … - Pediatric Research, 2009 - journals.lww.com
In preterm infants, low levels of Insulin like growth factor 1 (IGF-I) have been
associated with impaired growth and retinopathy of prematurity. Our objective
was to study safety and pharmacokinetics of iv administered rhIGF-I with ...
Cited by 1 - Related articles - All 5 versions

Systemic administration of bone morphogenetic proteins


S Vukicevic, P Simic, L Grgurevic, F … - Bone Morphogenetic Proteins: From Local to Systemic …, 2008 - Springer
Slobodan Vukicevic et al. ВМР-б increases bone volume in osteoporotic rats
Numerous studies have unequivocally demonstrated that recombinant human BMPs
induce new bone formation when administered locally in animals [17] and in ...
Related articles - All 3 versions

[CITATION] Normalization of the IGF-IGFBP-axis by Sustained Nightly Insulinization in Type 1 Diabetes …


P Bang
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