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Scholar Results 1 - 10 of about 42 citing Zhang: Sirolimus is associated with reduced islet engraftment and impaired β-cell function. (0.16 sec) 

mTOR inhibition by rapamycin prevents β-cell adaptation to hyperglycemia and …

- diabetesjournals.org
M Fraenkel, M Ketzinel-Gilad, Y Ariav, O Pappo, M … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—Unexpectedly, rapamycin worsened hyperglycemia in diabetic P. obesus without affecting
glycemia in normoglycemic controls. There was a 10-fold increase of serum insulin in diabetic P.
obesus compared with controls; ...
Cited by 20 - Related articles - BL Direct - All 4 versions

Heme oxygenase-1, carbon monoxide, and bilirubin induce tolerance in recipients …

- fasebj.org
SS Lee, W Gao, S Mazzola, MN Thomas, E Csizmadia, … - The FASEB Journal, 2007 - FASEB
Heme oxygenase-1 (HO-1) induction in, or carbon monoxide (CO), or bilirubin administration to,
donors and/or recipients frequently lead to long-term survival (>100 days) of DBA/2 islets into
B6AF1 recipients. We tested here ...
Cited by 17 - Related articles - BL Direct - All 4 versions

New onset diabetes mellitus after solid organ transplantation


PTT Pham, PCT Pham, GS Lipshutz, AH Wilkinson - … and Metabolism Clinics of …, 2007 - Elsevier
New onset diabetes mellitus after transplantation (NODAT) is a well-known complication following
solid organ transplantation and has been reported to occur in 4% to 25% of renal transplant
recipients, 2.5% to 25% of liver ...
Cited by 15 - Related articles - All 18 versions

Pancreatic islet cell transplant for treatment of diabetes


P Fiorina, A Secchi - Endocrinology and Metabolism Clinics of North …, 2007 - Elsevier
Islet cell transplantation recently has emerged as one the most promising therapeutic approaches to
improving glycometabolic control in type 1 diabetic patients, and, in many cases, to obtaining
insulin independence. Islet cell ...
Cited by 13 - Related articles - All 17 versions

Rapamycin impairs in vivo proliferation of islet beta-cells

- diabetesresearch.org [PDF] 
E Zahr, RD Molano, A Pileggi, H Ichii, SS Jose, N … - Transplantation, 2007 - journals.lww.com
Transplantation. Wolters Kluwer Health Logo. All Issues. ...
Cited by 12 - Related articles - BL Direct - All 4 versions

The use of exenatide in islet transplant recipients with chronic allograft dysfunction: …

- diabetesresearch.org [PDF] 
T Froud, RN Faradji, A Pileggi, S Messinger, DA … - Transplantation, 2008 - journals.lww.com
Tatiana Froud,1,2,3 Raquel N. Faradji,1,4 Antonello Pileggi,1,3 Shari Messinger,1,5 David A.
Baidal,1 Gaston M. Ponte,1 Pablo E. Cure,1 Kathy Monroy,1 Armando Mendez,1,4 Gennaro Selvaggi,1,3
Camillo Ricordi,1,3 and Rodolfo ...
Cited by 12 - Related articles - All 5 versions

Allogeneic islet transplantation


S Marzorati, A Pileggi, C Ricordi - Expert Opin. Biol. Ther., 2007 - informahealthcare.com
Significant progress has been made in the field of β-cell replacement therapies by islet
transplantation in patients with unstable Type 1 diabetes mellitus (T1DM). Recent clinical trials
have shown that islet ...
Cited by 11 - Related articles - BL Direct - All 6 versions

In vivo and in vitro effect of sirolimus on insulin secretion

- daegu.ac.kr [PDF] 
S Marcelli-Tourvieille, T Hubert, E Moerman, V Gmyr, … - Transplantation, 2007 - journals.lww.com
Skip Navigation Links Home > March 15, 2007 - Volume 83 - Issue 5 > In Vivo and In Vitro Effect of
Sirolimus on Insulin Secretio... ... 1 Department of Endocrinology and Metabolism and Endocrine
Surgery, INSERM Unit-M859, Diabetes ...
Cited by 11 - Related articles - BL Direct - All 6 versions

Immunosuppressive agents: effects on glucose and lipid metabolism


S Subramanian, DL Trence - Endocrinology and Metabolism Clinics of North …, 2007 - Elsevier
Since the first successful kidney transplant in 1959, transplantation medicine has evolved into
mainstream medical therapy. Such solid organ transplantation, however, would not have been possible
without the development of ...
Cited by 6 - Related articles - All 20 versions

The mammalian target of rapamycin regulates lipid metabolism in primary cultures …


NF Brown, M Stefanovic-Racic, IJ Sipula, G Perdomo - Metabolism, 2007 - Elsevier
The mammalian target of rapamycin (mTOR) is a conserved serine-threonine kinase that regulates cell
growth and metabolism in response to nutrient signals. However, the specific involvement of mTOR in
regulation of energy metabolism is ...
Cited by 6 - Related articles - All 14 versions


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