T Lundåsen, MC Hunt, LM Nilsson, S Sanyal, … - Biochemical and biophysical research communications, 2007 - Elsevier The metabolic regulator fibroblast growth factor 21 (FGF21) has antidiabetic
properties in animal models of diabetes and obesity. Using quantitative RT-PCR,
we here show that the hepatic gene expression of FGF21 is regulated by the ... Cited by 35 - Related articles - All 4 versions
- ►shouxi.net R Mussmann, M Geese, F Harder, S Kegel, U … - Journal of Biological Chemistry, 2007 - ASBMB Recent developments indicate that the regeneration of beta cell function and
mass in patients with diabetes is possible. A regenerative approach may
represent an alternative treatment option relative to current diabetes ... Cited by 29 - Related articles - All 7 versions
A Kharitonenkov, JD Dunbar, HA Bina, S … - Journal of cellular physiology, 2008 - interscience.wiley.com Fibroblast growth factor-21 (FGF-21) is a metabolic regulator that can influence
glucose and lipid control in diabetic rodents and primates. We demonstrate that
Klotho is an integral part of an activated FGF-21- Klotho-FGF receptor ... Cited by 26 - Related articles - BL Direct - All 2 versions
X Zhang, DCY Yeung, M Karpisek, D Stejskal … - Diabetes, 2008 - Am Diabetes Assoc RESULTS— Serum FGF21 levels in overweight/obese subjects were significantly
higher than in lean individuals. Serum FGF21 correlated positively with
adiposity, fasting insulin, and triglycerides but negatively with HDL ... Cited by 25 - Related articles - BL Direct - All 4 versions
- ►endojournals.org M Suzuki, Y Uehara, K Motomura-Matsuzaka, … - Molecular Endocrinology, 2008 - Endocrine Soc Fibroblast growth factor (FGF) 21, a structural relative of FGF23 that regulates
phosphate homeostasis, is a regulator of insulin-independent glucose transport
in adipocytes and plays a role in the regulation of body weight. It also ... Cited by 22 - Related articles - BL Direct - All 3 versions
P Arner, A Pettersson, PJ Mitchell, JD Dunbar … - FEBS letters, 2008 - Elsevier Fibroblast growth factor 21 (FGF21) is active in murine adipocytes and has
beneficial metabolic effects in animal models of type 2 diabetes mellitus. We
assessed whether FGF21 influences lipolysis in human adipocytes and 3T3-L1 ... Cited by 22 - Related articles - All 12 versions
N Stefan, K Kantartzis, HU Haring - Endocrine Reviews, 2008 - Endocrine Soc Type 2 diabetes and cardiovascular disease represent a serious threat to the
health of the population worldwide. Although overall adiposity and particularly
visceral adiposity are established risk factors for these diseases, in the ... Cited by 14 - Related articles - All 4 versions
T Coskun, HA Bina, MA Schneider, JD Dunbar … - Endocrinology, 2008 - Endocrine Soc Fibroblast growth factor 21 (FGF21) is a metabolic regulator that provides
efficient and durable glycemic and lipid control in various animal models.
However, its potential to treat obe- sity, a major health concern affecting ... Cited by 15 - Related articles - All 3 versions
- ►uky.edu [PDF] J Xu, DJ Lloyd, C Hale, S Stanislaus, M Chen, … - Diabetes, 2009 - Am Diabetes Assoc RESULTS—FGF21 dose dependently reduced body weight and whole-body fat mass in
DIO mice due to marked increases in total energy expenditure and physical
activity levels. FGF21 also reduced blood glucose, insulin, and lipid ... Cited by 15 - Related articles - All 5 versions
- ►endojournals.org [PDF] T Coskun, HA Bina, MA Schneider, JD Dunbar … - Endocrinology, 2008 - Endocrine Soc Page 1. 1 FGF21 Corrects Obesity in Mice Tamer Coskun, Holly A. Bina, Michael
A. Schneider, James D. Dunbar, Charlie C. Hu, Yanyun ... Cited by 12 - Related articles
