TJ Guzik, D Mangalat, R Korbut - Journal Of Physiology and Pharmacology, 2006 - jpp.krakow.pl Obesity and obesity related diseases are a major public health problem. Recent studies have
shown that fat tissue is not a simple energy storage organ, but exerts important endocrine and
immune functions. These are achieved predominantly through release of adipocytokines, ... Cited by 130 - Related articles - Cached - BL Direct - All 6 versions
PB Yu, CC Hong, C Sachidanandan, JL … - Nature chemical …, 2008 - pubmedcentral.nih.gov 1 Cardiovascular Research Center and Division of Cardiology, Department of Medicine, Massachusetts
General Hospital, Harvard Medical School, 149 13, th Street, Charlestown, Massachusetts
02129, USA. ... 2 Broad Institute of MIT and Harvard, 7 Cambridge Center, Cambridge, ... Cited by 74 - Related articles - BL Direct - All 5 versions
- ►ahajournals.org M Arad, CE Seidman, JG Seidman - Circulation research, 2007 - Am Heart Assoc AMP-activated protein kinase (AMPK) is a heterotrimeric enzyme that is expressed in most mammalian
tissues including cardiac muscle. Among the multiple biological processes influenced by
AMPK, regulation of fuel supply and energy-generating pathways in response to the ... Cited by 61 - Related articles - All 6 versions
- ►nih.gov KA Burns, JP Vanden Heuvel - BBA-Molecular and Cell Biology of Lipids, 2007 - Elsevier Peroxisome proliferator-activated receptors (PPARs) are members of the nuclear receptor superfamily
of transcription factors that respond to specific ligands by altering gene expression in a cell-,
developmental- and sex-specific manner. Three subtypes of this receptor have been ... Cited by 60 - Related articles - All 5 versions
M Ferron, E Hinoi, G Karsenty, P … - Proceedings of the …, 2008 - National Acad Sciences The osteoblast-specific secreted molecule osteocalcin behaves as a hormone regulating glucose
metabolism and fat mass in two mutant mouse strains. Here, we ask two questions: is the action
of osteocalcin on β cells and adipocytes elicited by the same concentrations of the ... Cited by 39 - Related articles - BL Direct - All 7 versions
- ►jimmunol.org CH Tang, YC Chiu, TW Tan, RS Yang, … - The Journal of …, 2007 - Am Assoc Immnol Articular adipose tissue is a ubiquitous component of human joints, and adiponectin is a protein
hormone secreted predominantly by differentiated adipocytes and involved in energy
homeostasis. We investigated the signaling pathway involved in IL-6 production caused ... Cited by 31 - Related articles - All 3 versions
- ►ajcn.org D Barb, CJ Williams, AK Neuwirth, CS … - American Journal of …, 2007 - Am Soc Nutrition Adiponectin, an adipocyte-secreted hormone that plays an important role in diabetes and cardiovascular
disease, may also be of importance in the development and progression of several
malignancies. Circulating adiponectin concentrations, which are determined mainly by ... Cited by 28 - Related articles - BL Direct - All 4 versions
- ►nih.gov A Suzuki, S Okamoto, S Lee, K Saito, T … - Molecular and Cellular …, 2007 - Am Soc Microbiol Leptin stimulates fatty acid oxidation in skeletal muscle through the activation of AMP-activated
protein kinase (AMPK) and the induction of gene expression, such as that for peroxisome
proliferator-activated receptor (PPAR ). We now show that leptin stimulates fatty acid ... Cited by 23 - Related articles - BL Direct - All 4 versions
L Li, L Wu, C Wang, L Liu, Y Zhao - Regulatory peptides, 2007 - Elsevier Adiponectin, an adipocyte-derived polypeptide hormone, plays an important role in regulating
fatty acid oxidation. β-oxidation of fatty acids supplies most of the cardiac energy and carnitine
palmitoyltransferase (CPT)-1 serves as a key regulator during this process. To ... Cited by 19 - Related articles - All 4 versions
- ►reproduction-online.org C Chabrolle, L Tosca, J Dupont - Reproduction, 2007 - Soc Reprod Fertility In mammals, adiponectin and its receptors (AdipoR1 and AdipoR2) mRNAs are expressed in
various tissues. However, the cellular expression and the role of adiponectin system have never
been investigated in rat ovary. Here, we report the presence of adiponectin, AdipoR1 and ... Cited by 17 - Related articles - BL Direct - All 2 versions