- ►cell.com H Ounissi-Benkalha, C Polychronakos - Trends in Molecular Medicine, 2008 - Elsevier Susceptibility to type 1 diabetes (T1D) is determined by complex interactions
between several genetic loci and environmental factors. Alleles at the human
leukocyte antigen (HLA) locus explain up to 50% of the familial clustering ... Cited by 13 - Related articles - All 4 versions
G Madadi, PS Dalvi, DD Belsham - Biochemical and Biophysical Research …, 2008 - Elsevier Whether the brain synthesizes insulin is currently debated. Two clonal,
immortalized mouse hypothalamic cell lines from e17, mHypoE-39 and mHypoE-46,
express insulin 2 (Ins2), but not Ins1. We analyzed regions necessary for ... Cited by 1 - Related articles - All 3 versions
A Kuroda, TA Rauch, I Todorov, HT Ku, IH Al- …, 2009 - pubmedcentral.nih.gov Genomic DNA samples from several tissues were bisulfite-treated and sequenced
which revealed that cytosine-guanosine dinucleotide (CpG) sites in both the
mouse Ins2 and human INS promoters are uniquely demethylated in insulin- ... Related articles - All 5 versions
C IONESCU-TÎRGOVIŞTE, C GUJA - paulescu.ro Based on our clinical and epidemiological data, we have sustained for a long
time the unitary character of the various phenotypes of the diabetic syndrome.
In this paper, we add several arguments sustaining that the unitary ... Related articles - View as HTML - All 2 versions
D Levi, C Polychronakos - Diabetologia, 2009 - Springer Abstract Aims/hypothesis The expression of tissue-specific self- antigens in the
thymus is essential for self-tolerance. Genetic susceptibility to type 1
diabetes correlates inversely with thymic insulin expression and, in mice, ... Related articles - All 2 versions
I Hansenne, C Louis, H Martens, G Dorban, C … - Neuroimmunomodulation, 2009 - eurothymaide.xtranet-isa.com The thymus is the primary lymphoid organ responsi- ble for T cell development
and central self-tolerance. In addition to effector T cell development, the
thymus shapes the repertoire of naturally occurring regulatory T cells ... Related articles - View as HTML - All 5 versions
ЮМ Колесник, ОМ Камишний, АВ Абрамов - ЕНДОКРИНОЛОГІЯ ENDOKRYNOLOGIA - nbuv.gov.ua 92 Ендокринологія 2007, Т. 12, № 1, с. 92 99
ХАРАКТЕРИСТИКА ІНСУЛІН EКСПРЕСУЮЧИХ КЛІТИН
ТИМУСА У НАЩАДКІВ ЩУРІВ З ... Related articles - View as HTML