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Scholar Results 1 - 10 of about 115 citing Zhang: Variant of transcription factor 7-like 2 (TCF7L2) gene and the risk of type 2 diabetes.... (0.11 sec) 

A genome-wide association study identifies novel risk loci for type 2 diabetes

- daegu.ac.kr [PDF] 
R Sladek, G Rocheleau, J Rung, C Dina, L … - Nature, 2007 - nature.com
Type 2 diabetes mellitus results from the interaction of environmental factors
with a combination of genetic variants, most of which were hitherto unknown. A
systematic search for these variants was recently made possible by the ...
Cited by 770 - Related articles - BL Direct - All 14 versions

Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes

- nih.gov
V Lyssenko, L Groop - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig
Genetic variants in the gene encoding for transcription factor-7–like 2
(TCF7L2) have been associated with type 2 diabetes (T2D) and impaired β cell
function, but the mechanisms have remained unknown. We therefore studied ...
Cited by 131 - Related articles - BL Direct - All 13 versions

TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a global …

- nthu.edu.tw [PDF] 
S Cauchi, Y El Achhab, H Choquet, C Dina, F … - Journal of Molecular Medicine, 2007 - Springer
Page 1. RAPID COMMUNICATION TCF7L2 is reproducibly associated with type
2 diabetes in various ethnic groups: a global meta-analysis ...
Cited by 94 - Related articles - BL Direct - All 4 versions

A genetic variation of the transcription factor 7-like 2 gene is associated with risk of type 2 …


M Horikoshi, K Hara, C Ito, R Nagai, P … - Diabetologia, 2007 - Springer
Page 1. SHORT COMMUNICATION A genetic variation of the transcription factor 7-like
2 gene is associated with risk of type 2 diabetes in the Japanese population ...
Cited by 59 - Related articles - BL Direct - All 4 versions

Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription …

- nih.gov
SA Schäfer, O Tschritter, F Machicao, C Thamer … - Diabetologia, 2007 - Springer
Page 1. ARTICLE Impaired glucagon-like peptide-1-induced insulin secretion in carriers
of transcription factor 7-like 2 (TCF7L2) gene polymorphisms ...
Cited by 54 - Related articles - BL Direct - All 9 versions

TCF7L2: the biggest story in diabetes genetics since HLA?

- nih.gov
E Zeggini, MI McCarthy - Diabetologia, 2007 - Springer
Much has been made over the past decade of the potential for genetics to advance
our understanding of the pathogenesis of type 2 diabetes and to 'revolutionise'
management of this condition [1]. Others have argued that these claims are ...
Cited by 51 - Related articles - BL Direct - All 6 versions

TCF7L2 polymorphisms modulate proinsulin levels and β-cell function in a British Europid …

- nih.gov
RJF Loos, PW Franks, RW Francis, I Barroso, … - Diabetes, 2007 - Am Diabetes Assoc
Rapidly accumulating evidence shows that common T-cell transcription factor
(TCF)7L2 polymorphisms confer risk of type 2 diabetes through unknown
mechanisms. We examined the association between four TCF7L2 single ...
Cited by 53 - Related articles - BL Direct - All 8 versions

Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8 and KCNJ11 with …

- diabetesjournals.org [PDF] 
S Omori, Y Tanaka, A Takahashi, H Hirose, … - Diabetes, 2007 - Am Diabetes Assoc
Page 1. Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX , SLC30A8 and KCNJ11 with
susceptibility to type 2 diabetes in a Japanese population ...
Cited by 53 - Related articles - BL Direct - All 4 versions

Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 …

- pubget.com [PDF] 
J Wang, J Kuusisto, M Vänttinen, T Kuulasmaa … - Diabetologia, 2007 - Springer
Page 1. ARTICLE Variants of transcription factor 7-like 2 (TCF7L2) gene predict
conversion to type 2 diabetes in the Finnish Diabetes ...
Cited by 50 - Related articles - BL Direct - All 4 versions

Polymorphisms within novel risk loci for type 2 diabetes determine β-cell function


H Staiger, F Machicao, N Stefan, O Tschritter, … - PLoS One, 2007 - pubmedcentral.nih.gov
Background. Type 2 diabetes arises when insulin resistance-induced compensatory
insulin secretion exhausts. Insulin resistance and/or b-cell dysfunction result
from the interaction of environmental factors (high-caloric diet and ...
Cited by 47 - Related articles - All 5 versions


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