- ►daegu.ac.kr [PDF] R Sladek, G Rocheleau, J Rung, C Dina, L Shen, D … - Nature, 2007 - nature.com Type 2 diabetes mellitus results from the interaction of environmental factors with a combination
of genetic variants, most of which were hitherto unknown. A systematic search for these variants
was recently made possible by the development of high-density arrays that permit the ... Cited by 778 - Related articles - BL Direct - All 14 versions
- ►nih.gov V Lyssenko, L Groop - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig Genetic variants in the gene encoding for transcription factor-7–like 2 (TCF7L2) have been associated
with type 2 diabetes (T2D) and impaired β cell function, but the mechanisms have remained
unknown. We therefore studied prospectively the ability of common variants in TCF7L2 to ... Cited by 136 - Related articles - BL Direct - All 13 versions
- ►nthu.edu.tw [PDF] S Cauchi, Y El Achhab, H Choquet, C Dina, F … - Journal of Molecular …, 2007 - Springer Page 1. RAPID COMMUNICATION TCF7L2 is reproducibly associated with type 2
diabetes in various ethnic groups: a global meta-analysis Stéphane Cauchi & Younes
El Achhab & Hélène Choquet & Christian Dina & Franz Krempler & ... Cited by 99 - Related articles - BL Direct - All 4 versions
M Horikoshi, K Hara, C Ito, R Nagai, P Froguel, T … - Diabetologia, 2007 - Springer Page 1. SHORT COMMUNICATION A genetic variation of the transcription factor 7-like
2 gene is associated with risk of type 2 diabetes in the Japanese population M. Horikoshi
& K. Hara & C. Ito & R. Nagai & P. Froguel & T. Kadowaki ... Cited by 59 - Related articles - BL Direct - All 4 versions
- ►nih.gov SA Schäfer, O Tschritter, F Machicao, C Thamer, N … - Diabetologia, 2007 - Springer Page 1. ARTICLE Impaired glucagon-like peptide-1-induced insulin secretion in carriers of
transcription factor 7-like 2 (TCF7L2) gene polymorphisms SA Schäfer & O. Tschritter & F.
Machicao & C. Thamer & N. Stefan & B. Gallwitz & JJ Holst & JM Dekker & ... Cited by 57 - Related articles - BL Direct - All 9 versions
- ►nih.gov E Zeggini, MI McCarthy - Diabetologia, 2007 - Springer Much has been made over the past decade of the potential for genetics to advance our understanding
of the pathogenesis of type 2 diabetes and to 'revolutionise' management of this condition
[1]. Others have argued that these claims are premature [2]; indeed, some have ... Cited by 51 - Related articles - BL Direct - All 6 versions
RJF Loos, PW Franks, RW Francis, I Barroso, FM … - Diabetes, 2007 - Am Diabetes Assoc Rapidly accumulating evidence shows that common T-cell transcription factor (TCF)7L2 polymorphisms
confer risk of type 2 diabetes through unknown mechanisms. We examined the association between
four TCF7L2 single nucleotide polymorphisms (SNPs), including rs7903146, and ... Cited by 53 - Related articles - BL Direct - All 8 versions
- ►pubget.com [PDF] J Wang, J Kuusisto, M Vänttinen, T Kuulasmaa, J … - Diabetologia, 2007 - Springer Page 1. ARTICLE Variants of transcription factor 7-like 2 (TCF7L2) gene predict
conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are
associated with impaired glucose regulation and impaired insulin secretion ... Cited by 51 - Related articles - BL Direct - All 4 versions
T Hayashi, Y Iwamoto, K Kaku, H Hirose, S Maeda - Diabetologia, 2007 - Springer Abstract Aims/hypothesis The transcription factor 7-like 2 gene (TCF7L2) has been shown to
be strongly associated with an increased risk of type 2 diabetes in white populations. To further
investigate the involvement of TCF7L2 in confer- ring susceptibility to type 2 diabetes, we ... Cited by 46 - Related articles - BL Direct - All 3 versions
- ►diabetesjournals.org ER Pearson, LA Donnelly, C Kimber, A Whitley, ASF … - Diabetes, 2007 - Am Diabetes Assoc RESEARCH DESIGN AND METHODS— The DARTS/MEMO (Diabetes Audit and Research
Tayside/Medicines Monitoring Unit) collaboration database includes prescribing,
biochemistry, and clinical phenotype of all patients with diabetes within Tayside, ... Cited by 45 - Related articles - BL Direct - All 5 versions