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Scholar Results 1 - 10 of about 139 citing Scott: Association of transcription factor 7-like 2 (TCF7L2) variants with type 2 diabetes.... (0.11 sec) 

A genome-wide association study identifies novel risk loci for type 2 diabetes

- daegu.ac.kr [PDF] 
R Sladek, G Rocheleau, J Rung, C Dina, L Shen, D … - Nature, 2007 - nature.com
Type 2 diabetes mellitus results from the interaction of environmental factors with a combination
of genetic variants, most of which were hitherto unknown. A systematic search for these variants
was recently made possible by the development of high-density arrays that permit the ...
Cited by 778 - Related articles - BL Direct - All 14 versions

Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 …

- nih.gov
V Lyssenko, L Groop - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig
Genetic variants in the gene encoding for transcription factor-7–like 2 (TCF7L2) have been associated
with type 2 diabetes (T2D) and impaired β cell function, but the mechanisms have remained
unknown. We therefore studied prospectively the ability of common variants in TCF7L2 to ...
Cited by 136 - Related articles - BL Direct - All 13 versions

TCF7L2 is reproducibly associated with type 2 diabetes in various ethnic groups: a …

- nthu.edu.tw [PDF] 
S Cauchi, Y El Achhab, H Choquet, C Dina, F … - Journal of Molecular …, 2007 - Springer
Page 1. RAPID COMMUNICATION TCF7L2 is reproducibly associated with type 2
diabetes in various ethnic groups: a global meta-analysis Stéphane Cauchi & Younes
El Achhab & Hélène Choquet & Christian Dina & Franz Krempler & ...
Cited by 99 - Related articles - BL Direct - All 4 versions

A genetic variation of the transcription factor 7-like 2 gene is associated with risk of …


M Horikoshi, K Hara, C Ito, R Nagai, P Froguel, T … - Diabetologia, 2007 - Springer
Page 1. SHORT COMMUNICATION A genetic variation of the transcription factor 7-like
2 gene is associated with risk of type 2 diabetes in the Japanese population M. Horikoshi
& K. Hara & C. Ito & R. Nagai & P. Froguel & T. Kadowaki ...
Cited by 59 - Related articles - BL Direct - All 4 versions

Impaired glucagon-like peptide-1-induced insulin secretion in carriers of …

- nih.gov
SA Schäfer, O Tschritter, F Machicao, C Thamer, N … - Diabetologia, 2007 - Springer
Page 1. ARTICLE Impaired glucagon-like peptide-1-induced insulin secretion in carriers of
transcription factor 7-like 2 (TCF7L2) gene polymorphisms SA Schäfer & O. Tschritter & F.
Machicao & C. Thamer & N. Stefan & B. Gallwitz & JJ Holst & JM Dekker & ...
Cited by 57 - Related articles - BL Direct - All 9 versions

TCF7L2: the biggest story in diabetes genetics since HLA?

- nih.gov
E Zeggini, MI McCarthy - Diabetologia, 2007 - Springer
Much has been made over the past decade of the potential for genetics to advance our understanding
of the pathogenesis of type 2 diabetes and to 'revolutionise' management of this condition
[1]. Others have argued that these claims are premature [2]; indeed, some have ...
Cited by 51 - Related articles - BL Direct - All 6 versions

TCF7L2 polymorphisms modulate proinsulin levels and β-cell function in a British …


RJF Loos, PW Franks, RW Francis, I Barroso, FM … - Diabetes, 2007 - Am Diabetes Assoc
Rapidly accumulating evidence shows that common T-cell transcription factor (TCF)7L2 polymorphisms
confer risk of type 2 diabetes through unknown mechanisms. We examined the association between
four TCF7L2 single nucleotide polymorphisms (SNPs), including rs7903146, and ...
Cited by 53 - Related articles - BL Direct - All 8 versions

Variants of transcription factor 7-like 2 (TCF7L2) gene predict conversion to type 2 …

- pubget.com [PDF] 
J Wang, J Kuusisto, M Vänttinen, T Kuulasmaa, J … - Diabetologia, 2007 - Springer
Page 1. ARTICLE Variants of transcription factor 7-like 2 (TCF7L2) gene predict
conversion to type 2 diabetes in the Finnish Diabetes Prevention Study and are
associated with impaired glucose regulation and impaired insulin secretion ...
Cited by 51 - Related articles - BL Direct - All 4 versions

Replication study for the association of TCF7L2 with susceptibility to type 2 …


T Hayashi, Y Iwamoto, K Kaku, H Hirose, S Maeda - Diabetologia, 2007 - Springer
Abstract Aims/hypothesis The transcription factor 7-like 2 gene (TCF7L2) has been shown to
be strongly associated with an increased risk of type 2 diabetes in white populations. To further
investigate the involvement of TCF7L2 in confer- ring susceptibility to type 2 diabetes, we ...
Cited by 46 - Related articles - BL Direct - All 3 versions

Variation in TCF7L2 influences therapeutic response to sulfonylureas

- diabetesjournals.org
ER Pearson, LA Donnelly, C Kimber, A Whitley, ASF … - Diabetes, 2007 - Am Diabetes Assoc
RESEARCH DESIGN AND METHODS— The DARTS/MEMO (Diabetes Audit and Research
Tayside/Medicines Monitoring Unit) collaboration database includes prescribing,
biochemistry, and clinical phenotype of all patients with diabetes within Tayside, ...
Cited by 45 - Related articles - BL Direct - All 5 versions


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