- ►nih.gov BE Levin - The Journal of Physiology, 2007 - Physiological Soc There is a widespread obesity epidemic in the developed world which is having an
adverse impact on the health of affected individuals. Many of the afflicted have
a genetic predisposition to become obese. These individuals become obese ... Cited by 13 - Related articles - BL Direct - All 8 versions
M Coghlan, B Leighton - Expert Opin. Investig. Drugs, 2008 - informahealthcare.com Type 2 diabetes is a chronic metabolic disease that adversely affects both the
quality and longevity of life. The disease is characterised by elevated blood
glucose (hyperglycaemia) that is associated with microvascular ... Cited by 12 - Related articles - BL Direct - All 6 versions
M Saberi, MA Bohland, CM Donovan - Diabetes, 2008 - Am Diabetes Assoc RESULTS—Inducing hypoglycemia slowly, at a rate of −0.09 mmol · l −1 ·
min −1 , resulted in a 26-fold increase in epinephrine (23.39 ± 0.62 nmol/l)
and 12-fold increase in norepinephrine (11.42 ± 0.92 nmol/l) for controls ... Cited by 7 - Related articles - BL Direct - All 4 versions
- ►yale.edu [PDF] BE Levin, TC Becker, J Eiki, BB Zhang, AA … - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—The counterregulatory response to insulin-induced hypoglycemia is
mediated by the ventromedial hypothalamus (VMH), which contains specialized
glucosensing neurons, many of which use glucokinase (GK) as the ... Cited by 7 - Related articles - BL Direct - All 5 versions
- ►physiology.org L Kang, NM Sanders, AA Dunn-Meynell, LD … - … Journal of Physiology- Regulatory, Integrative and …, 2008 - Am Physiological Soc Antecedent insulin-induced hypoglycemia (IIH) reduces adrenomedullary responses
(AMR) to subsequent bouts of hypoglycemia. The ventromedial hypothalamus [VMH:
arcuate (ARC) + ventromedial nuclei] contains glucosensing neurons, which ... Cited by 6 - Related articles - BL Direct - All 3 versions
- ►nih.gov RS Sherwin - Diabetes, 2008 - Am Diabetes Assoc My story begins 30 years ago. Bill Tamborlane came to me with a portable,
battery-powered pump being used in pediatrics to infuse the iron-chelating drug
desferrioxamine continuously via the subcutaneous route into children with ... Cited by 7 - Related articles - All 5 versions
- ►nih.gov [PDF] KW Williams, R Coppari, JK Elmquist - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig AMP-activated protein kinase (AMPK) has emerged as a metabolic “fuel gauge,”
which oscillates between anabolic and catabolic processes that ultimately
influence energy balance. A study in this issue of the JCI by Claret et al. ... Cited by 2 - Related articles - BL Direct - All 6 versions
- ►pnas.org A Kohyama-Koganeya, YJ Kim, M Miura, Y … - Proceedings of the National Academy of Sciences, 2008 - National Acad Sciences Glucose, one of the most important nutrients for animals, acts as a regulatory
signal that controls the secretion of hormones, such as insulin, by endocrine
tissues. However, how organisms respond to extracellular glucose and how ... Cited by 2 - Related articles - All 8 versions
- ►shouxi.net S Vidarsdottir, PAM Smeets, DL Eichelsheim, … - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE—The hypothalamus plays a critical role in the regulation of energy
balance and fuel flux. Glucose ingestion inhibits hypothalamic neuronal activity
in healthy humans. We hypothesized that hypothalamic neuronal activity in ... Cited by 1 - Related articles - BL Direct - All 6 versions
