P Schönfeld, L Wojtczak - Free Radical Biology and Medicine, 2008 - Elsevier Long-chain nonesterified (“free”) fatty acids (FFA) and some of their derivatives and
metabolites can modify intracellular production of reactive oxygen species (ROS), in particular O 2
– and H 2 O 2 . In mitochondria, ... Cited by 17 - Related articles - All 2 versions
- ►uni-graz.at [PDF] WF Graier, M Trenker, R Malli - Cell Calcium, 2008 - Elsevier The underlying molecular action of the novel uncoupling proteins 2 and 3 (UCP2 and UCP3) is still
under debate. The proteins have been implicated in many cell functions, including the regulation of
insulin secretion and regulation of ... Cited by 10 - Related articles - All 4 versions
- ►jbc.org R Kohli, X Pan, P Malladi, MS Wainwright, PF … - Journal of Biological …, 2007 - ASBMB Abnormal dietary intake of macronutrients is implicated in the development of obesity and fatty
liver disease. Steatosis develops in cultured hepatocytes exposed to medium containing either a high
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F Cardona, I Tunez, I Tasset, M Murri, FJ Tinahones - Clinical Biochemistry, 2008 - Elsevier 17 controls and two groups with hypertriglyceridemia: 43 without the metabolic syndrome (TG-non-MS)
and 29 with the metabolic syndrome (TG-MS). All subjects underwent a 60 g fat overload. Baseline
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J Pi, Y Bai, KW Daniel, D Liu, O Lyght, D Edelstein, M … - Endocrinology, 2009 - Endocrine Soc Uncoupling protein (UCP) 2 is a widely expressed mitochondrial protein whose precise function is
still unclear but has been linked to mitochondria-derived reactive oxygen species production. Thus,
the chronic absence of UCP2 has the ... Cited by 8 - Related articles - All 3 versions
- ►diabetesjournals.org C Leloup, C Tourrel-Cuzin, C Magnan, M Karaca, J … - Diabetes, 2009 - Am Diabetes Assoc RESULTS—Transient glucose increase from 5.5 to 16.7 mmol/l stimulated ROS generation, which was
reversed by antioxidants. Insulin secretion was dose dependently blunted by antioxidants and highly
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C Le Foll, BG Irani, C Magnan, AA Dunn- … - American Journal of …, 2009 - Am Physiological Soc We assessed the mechanisms by which specialized hypothalamic ventromedial nucleus (VMN) neurons
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- ►nih.gov M Siervo, JC Wells, G Cizza - Horm Metab Res, 2009 - thieme-connect.com The Thrifty Gene hypothesis theorizes that during evolution a set of genes has been selected to
ensure survival in environments with limited food supply and marked seasonality. Contemporary
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B Kuhla, S Kuhla, PE Rudolph, D Albrecht, CC Metges - Proteomics, 2007 - ncbi.nlm.nih.gov The hypothalamus is the central regulatory unit that balances a number of body functions including
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R Kohli, X Pan, P Malladi, MS Wainwright, PF … - Journal of Biological …, 2007 - ASBMB Running title: Mitochondrial ROS signal steatosis via PI3-kinase Keywords: ETC, HFFA, MCD, mROS,
NAFLD, PI 3-kinase, PTEN, SOD, hepatocytes. Address correspondence to: Peter F. Whitington,
Children's Memorial Research ... Cited by 1 - Related articles - All 2 versions
