- ►joslinresearch.org [PDF] H Hakonarson, SFA Grant, JP Bradfield, L Marchand, … - Nature, 2007 - nature.com Type 1 diabetes (T1D) in children results from autoimmune destruction of pancreatic beta
cells, leading to insufficient production of insulin 1 . A number of genetic determinants of T1D
have already been established through candidate gene studies, primarily within the major ... Cited by 153 - Related articles - BL Direct - All 7 versions
- ►diabetesjournals.org M Pietropaolo, E Barinas-Mitchell, LH Kuller - Diabetes, 2007 - Am Diabetes Assoc Diabetes is an emblematic example of a heterogeneous disease. Systemic inflammation has
emerged as a prominent factor in the type 2 diabetes pathoetiology, but it remains ill-defined
in type 1 diabetes. There is a wide spectrum of associations between inflammatory ... Cited by 11 - Related articles - BL Direct - All 10 versions
SD Burke, H Dong, AD Hazan, BA Croy - Diabetes, 2007 - Am Diabetes Assoc OBJECTIVE—Pregnant diabetic women are at a 4–12 times higher risk for preeclampsia, an
urgent acute-onset complication of mid- to late gestation, than normal pregnant women. Hallmarks
of preeclampsia are hypertension, proteinuria, and incomplete modification of ... Cited by 9 - Related articles - BL Direct - All 4 versions
A Alba, R Planas, X Clemente, J Carrillo, … - Clinical and …, 2008 - pubmedcentral.nih.gov The destruction of β cells by the islet infiltrating lymphocytes causes type 1 diabetes. Transgenic
mice models expressing interferon (IFN)-β in β cells, in the non-obese diabetic (NOD) strain and
in a diabetes-free, major histocompatibility complex-matched, homologous strain, the non- ... Cited by 5 - Related articles - BL Direct - All 6 versions
- ►diabetesjournals.org V Butty, C Campbell, D Mathis, C Benoist - Diabetes, 2008 - Am Diabetes Assoc OBJECTIVE—The unfolding of type 1 diabetes involves a number of steps: defective immunological
tolerance, priming of anti-islet autoimmunity, and destruction of insulin-producing β-cells. A number
of genetic loci contribute to susceptibility to type 1 diabetes, but it is unclear which stages ... Cited by 4 - Related articles - All 5 versions
RD Levinson, Z Du, L Luo, D Monnet, T Tabary, AP … - Genes and Immunity, 2008 - nature.com Birdshot chorioretinopathy (BCR), a chronic ocular inflammatory disease with characteristic choroidal
lymphocytic infiltrates, has been strongly associated with human leukocyte antigen
(HLA)-A29. Although HLA-A29 occurs frequently in all populations, BCR affects only a ... Cited by 4 - Related articles - BL Direct - All 5 versions
MN Peraldi, J Berrou, N Dulphy, A … - The Journal of …, 2009 - Am Assoc Immnol To characterize the immune defect of patients with end-stage renal disease (ESRD), we performed
NK cell subset analysis in 66 patients with ESRD treated by hemodialysis (n = 59) or peritoneal
dialysis (n = 7). Compared with healthy blood donors, patients undergoing chronic ... Cited by 3 - Related articles - All 2 versions
E Tskitishvili, Y Komoto, Y Kinugasa, T … - American Journal of …, 2007 - interscience.wiley.com The human tumor-associated receptor-binding cancer antigen expressed on SiSo cells
(RCAS1) is considered to play a role in the inhibition of the maternal immune response during
pregnancy. The aim of our study was to investigate the expression of RCAS1 protein in ... Cited by 3 - Related articles - BL Direct - All 3 versions
M Pietropaolo, JM Surhigh, PW Nelson, GS Eisenbarth - Diabetes, 2008 - Am Diabetes Assoc For nonimmunologists, a daunting and rapidly evolving immunologic vocabulary, our incomplete
understanding of both normal and abnormal immune function, and multiple interrelated complex
immune cellular pathways can be a barrier to using basic immunology to understand and ... Cited by 4 - Related articles - All 9 versions
S Belanger, LH Tai, SK Anderson, AP … - Genes and …, 2008 - pubmedcentral.nih.gov The mouse Ly49 and human killer cell immunoglobulin-like receptors (KIR) gene clusters encode
activating and inhibitory class I MHC receptors on natural killer (NK) cells. A direct correlation
between the presence of multiple activating KIR and various human autoimmune ... Cited by 2 - Related articles - All 4 versions
