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Scholar Results 1 - 10 of 12 citing Möllsten: A functional polymorphism in the manganese superoxide dismutase gene and diabetic.... (0.11 sec) 

Trends in oxidative aging theories

- litagion.com [PDF] 
FL Muller, MS Lustgarten, Y Jang, A Richardson, H … - Free Radical Biology and …, 2007 - Elsevier
The early observations on the rate-of-living theory by Max Rubner and the report by Gershman
that oxygen free radicals exist in vivo culminated in the seminal proposal in the 1950s by Denham
Harman that reactive oxygen species are a cause of aging (free radical theory of aging). ...
Cited by 130 - Related articles - All 13 versions

Oxidative stress as a major culprit in kidney disease in diabetes

- diabetesjournals.org
JM Forbes, MT Coughlan, ME Cooper - Diabetes, 2008 - Am Diabetes Assoc
It is postulated that localized tissue oxidative stress is a key component in the development of
diabetic nephropathy. There remains controversy, however, as to whether this is an early link
between hyperglycemia and renal disease or develops as a consequence of other ...
Cited by 45 - Related articles - All 3 versions

Genetic factors in diabetic nephropathy

- asnjournals.org
BI Freedman, M Bostrom, P Daeihagh, DW … - Clinical Journal of the …, 2007 - Am Soc Nephrol
Several genes that predispose to type 2 diabetes have recently been identified. In addition to
the recognized and powerful effects of environmental factors, there is abundant evidence in support
of genetic susceptibility to the microvascular complication of nephropathy in individuals ...
Cited by 25 - Related articles - All 3 versions

The manganese superoxide dismutase Val16Ala polymorphism is associated with …


L Liu, T Zheng, N Wang, F Wang, M Li, J Jiang, R … - Molecular and cellular …, 2009 - Springer
Abstract The aim of the present study was to evaluate the relationship of the manganese superoxide
dismutase (MnSOD) Val16Ala (V16A) polymorphism with type 2 diabetes mellitus (T2DM) and
diabetic nephropathy (DN) in Chinese patients, a case-control study was performed. This ...
Cited by 4 - Related articles - All 2 versions

Zinc supplementation partially prevents renal pathological changes in diabetic rats


Y Tang, Q Yang, J Lu, X Zhang, D Suen, Y Tan, L … - The Journal of Nutritional …, 2009 - Elsevier
We have demonstrated that Zn supplementation mediated up-regulation of cardiac metallothionein
(MT) as a potent antioxidant prevented the development of diabetic cardiomyopathy. The present
study was undertaken to test whether induction of renal MT synthesis by Zn ...
Cited by 1 - Related articles

[PDF] Genetic aspects of outcome in kidney transplantation: cytokine and thrombosis …


N Alakulppi - oa.doria.fi
To be publicly discussed, with the permission of the Faculty of Biosciences, University of
Helsinki, in the Nevanlinna Auditorium of the Finnish Red Cross Blood Service, Kivihaantie
7, Helsinki, on January 18th, 2008, at 12 noon. ... ACADEMIC DISSERTATIONS FROM ...
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The structural biochemistry of the superoxide dismutases


JJP Perry, DS Shin, ED Getzoff, JA Tainer - … et Biophysica Acta (BBA)-Proteins & …, 2009 - Elsevier
The discovery of superoxide dismutases (SODs), which convert superoxide radicals to hydrogen
peroxide, has been termed the most important discovery of modern biology never to win a Nobel
Prize. Here, we review the reasons this discovery has been underappreciated, as well as ...

Manganese superoxide dismutase: effect of the ala16val polymorphism on protein, …


BL McAtee, JD Yager - Molecular and Cellular Biochemistry - Springer
Abstract The manganese superoxide dismutase (MnSOD) ala16val polymorphism has been
associated with various diseases including breast cancer. In the present study, we investigated
levels of MnSOD protein, enzymatic activity, and mRNA with respect to MnSOD genotype ...
Related articles - All 2 versions

[PDF] Analysis of functional genetic polymorphisms in prostate cancer and type 2 …


RJ Strawbridge - diss.kib.ki.se
Prostate cancer and type 2 diabetes are complex diseases, the genetic and environmental basis
of which are not well established. Epidimiology suggests a link between the two diseases, with
type 2 diabetes redusing the risk of prostate cancer, and faily history of prostate cancer ...
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Genome Study of Kidney Disease in the Age of Post Genome-Sequencing


K Okamoto, K Tokunaga, T Fujita, E … - Endocrine, Metabolic &# …, 2008 - ingentaconnect.com
Page 1. Endocrine, Metabolic & Immune Disorders - Drug Targets, 2008, 8, 173-183
173 1871-5303/08 $55.00+.00 © 2008 Bentham Science Publishers Ltd. Genome Study
of Kidney Disease in the Age of Post Genome-Sequencing ...
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