- ►nih.gov T Nir, DA Melton, Y Dor - Journal of Clinical Investigation, 2007 - Am Soc Clin Investig The mechanisms that regulate pancreatic β cell mass are poorly understood.
While autoimmune and pharmacological destruction of insulin-producing β cells
is often irreversible, adult β cell mass does fluctuate in response to ... Cited by 99 - Related articles - BL Direct - All 8 versions
- ►diabetesjournals.org S Yatoh, R Dodge, T Akashi, A Omer, A … - Diabetes, 2007 - Am Diabetes Assoc To test whether pancreatic duct cells are in vitro progenitors, they were
purified from dispersed islet-depleted human pancreatic tissue using CA19-9
antibody. The purified fraction was almost entirely CK19 + with no insulin ... Cited by 39 - Related articles - BL Direct - All 5 versions
G Parnaud, D Bosco, T Berney, F Pattou, J … - Diabetologia, 2008 - Springer Abstract Aims/hypothesis The aim of the study was to determine whether purified
beta cells can replicate in vitro and whether this is enhanced by extracellular
matrix (ECM) and growth factors. Methods Human beta cells were purified by ... Cited by 38 - Related articles - BL Direct - All 3 versions
X Meng, TE Ichim, J Zhong, A Rogers, Z Yin, … - Journal of Translational Medicine, 2007 - translational-medicine.com Angiogenesis is a critical component of the proliferative endometrial phase of
the menstrual cycle. Thus, we hypothesized that a stem cell-like population
exist and can be isolated from menstrual blood. Mononuclear cells collected ... Cited by 35 - Related articles - Cached - All 17 versions
- ►alphamedpress.org B Davani, L Ikonomou, BM Raaka, E Geras- … - Stem Cells, 2007 - AlphaMed Press Islet transplantation offers improved glucose homeostasis in diabetic patients,
but transplantation of islets is limited by the supply of donor pancreases.
Undifferentiated precursors hold promise for cell therapy because they can ... Cited by 27 - Related articles - BL Direct - All 5 versions
- ►diabetesjournals.org HA Russ, Y Bar, P Ravassard, S Efrat - Diabetes, 2008 - Am Diabetes Assoc RESULTS— β-Cells were efficiently and specifically labeled by the dual virus
system. Label + , insulin − cells derived from β-cells were shown to
proliferate for a maximum of 16 population doublings, with an approximate ... Cited by 19 - Related articles - All 4 versions
M Liu, ZC Han - J Cell Mol Med, 2008 - interscience.wiley.com Mesenchymal stem cells (MSCs) can be derived from adult bone marrow, fat and
several foetal tissues. In vitro, MSCs have the capacity to differentiate into
multiple mesodermal and non-mesodermal cell lineages. Besides, MSCs possess ... Cited by 13 - Related articles - All 3 versions
S Efrat - Advanced drug delivery reviews, 2008 - Elsevier Beta-cell replacement is considered the optimal treatment for type 1 diabetes,
however, it is hindered by a shortage of human organ donors. Given the
difficulty of expanding adult beta cells in vitro, stem/progenitor cells, ... Cited by 12 - Related articles - All 4 versions
R Gallo, F Gambelli, B Gava, F Sasdelli, V … - Cell Death & Differentiation, 2007 - nature.com Cellular models and culture conditions for in vitro expansion of
insulin-producing cells represent a key element to develop cell therapy for
diabetes. Initial evidence that human -cells could be expanded after ... Cited by 13 - Related articles - BL Direct - All 5 versions
- ►alphamedpress.org CA Fraker, S Alvarez, P Papadopoulos, J … - Stem Cells, 2007 - AlphaMed Press Despite progress in our knowledge about pancreatic islet specification, most
attempts at differentiating stem/progenitor cells into functional,
transplantable β cells have met only with moderate success thus far. A ... Cited by 11 - Related articles - BL Direct - All 6 versions
