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Scholar Results 1 - 7 of 7 citing Kim: Crystal structure of the major diabetes autoantigen insulinoma-associated protein 2.... (0.10 sec) 

COOH-terminal clustering of autoantibody and T-cell determinants on the structure …

- diabetesjournals.org
G Fenalti, CS Hampe, Y Arafat, RHP Law, JP Banga, IR … - Diabetes, 2008 - Am Diabetes Assoc
RESULTS—The COOH-terminal region on GAD65 was the major autoantigenic site. B-cell epitopes
were distributed within two separate clusters around different faces of the COOH-terminal
domain. Inclusion of epitope sites in the pyridoxal phosphate–and NH 2 -terminal ...
Cited by 8 - Related articles - BL Direct - All 3 versions

Use of MHC II structural features in the design of vaccines for organ-specific …


AK Moustakas, GK Papadopoulos - Current Pharmaceutical Design, 2009 - ingentaconnect.com
Use of MHC II Structural Features in the Design of Vaccines for Organ- Specific Autoimmune
Diseases ... 1Department of Organic Farming, Educational Technological Institute of Ionian
Islands, GR27100 Argostoli, Cephallonia, GREECE; 2Laboratory of Biochemistry and ...
Cited by 2 - Related articles

Autoantibodies and associated T-cell responses to determinants within the 831– …


SM Weenink, J Lo, CR Stephenson, PA McKinney, R … - Journal of Autoimmunity, 2009 - Elsevier
B-cells influence T-cell reactivity by facilitating antigen presentation, but the role of
autoantibody-secreting B-cells in regulating T-cell responses in Type 1 diabetes is poorly
defined. The aims of this study were to characterise epitopes on the IA-2 autoantigen for ...
Cited by 1 - Related articles - All 2 versions

Regulation of Insulin Granule Turnover in Pancreatic {beta}-Cells by Cleaved …

- jbc.org
M Trajkovski, H Mziaut, S Schubert, Y Kalaidzidis, A … - Journal of Biological …, 2008 - ASBMB
Insulin maintains homeostasis of glucose by promoting its uptake into cells from the blood. Hyperglycemia
triggers secretion of insulin from pancreatic β-cells. This process is mediated by secretory granule
exocytosis. However, how β-cells keep granule stores relatively constant is still unknown. ...
Cited by 1 - Related articles - All 3 versions

[PDF] Regulation of Insulin Granule Turnover in Pancreatic ß-Cells by Cleaved ICA512


M Solimena - THE JOURNAL OF BIOLOGICAL CHEMISTRY, 2008 - ASBMB
Insulin maintains homeostasis of glucose by promoting its uptake into cells from the blood. Hyperglycemia
triggers secretion of insulin from pancreatic ß-cells. This process is mediated by secretory granule
exocytosis. However, how ß-cells keep granule stores relatively constant is still unknown. ...
Related articles

C-terminal clustering of autoantibody and T cell determinants on the structure of …


JCW PhD, AMB PhD, MJR PhD - Am Diabetes Assoc
Gustavo Fenalti (BSc (Pharm)1, Christiane S. Hampe (PhD)2, Yasir Arafat (BSc (Eng)1, Ruby
HP Law (PhD)1, J. Paul Banga (PhD)3, Ian R. Mackay (MD)1, James C. Whisstock (PhD)1 ,,
Ashley M. Buckle (PhD)1, Merrill J. Rowley (PhD)1 ... 1Department of Biochemistry and ...
Related articles

Approaches in type 1 diabetes research: A status report


O Raha, S Chowdhury, S Dasgupta, P … - International Journal of …, 2009 - ijddc.com
Type 1 diabetes is a multifactorial disease with an early age of onset, in which the insulin producing
β cell of the pancreas are destroyed because of autoimmunity. It is the second most common
chronic disease in children and account for 5% to 10% of all diagnosed cases of ...
Related articles - Cached - All 2 versions


 


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