PC Butler, JJ Meier, AE Butler, A Bhushan - Nature clinical practice. Endocrinology & metabolism, 2007 - ncbi.nlm.nih.gov Replication of beta cells is an important source of beta-cell expansion in early
childhood. The recent linkage of type 2 diabetes with several transcription
factors involved in cell cycle regulation implies that growth of the ... Cited by 41 - Related articles - BL Direct - All 3 versions
- ►171.66.122.45 MP Keller, YJ Choi, P Wang, D Belt Davis, ME … - Genome Research, 2008 - 171.66.122.45 Insulin resistance is necessary but not sufficient for the development of type 2
diabetes. Diabetes results when pancreatic beta-cells fail to compensate for
insulin resistance by increasing insulin production through an expansion of ... Cited by 27 - Related articles - BL Direct - All 15 versions
V Sordi, F Bertuzzi, L Piemonti - Regen. Med., 2008 - Future Medicine In both Type 1 and 2 diabetes, insufficient numbers of insulin-producing
β-cells are a major cause of defective control of blood glucose and its
complications. Restoration of damaged β-cells by endocrine pancreas ... Cited by 5 - Related articles - BL Direct - All 4 versions
C Hinault, J Hu, BF Maier, RG Mirmira, RN … - Diabetes Obes Metab, 2008 - interscience.wiley.com One of the major challenges for developmental biologists and investigators in
the field of diabetes over the last few decades has been to dissect the origin
of pancreatic endocrine cells and to accurately understand the mechanisms ... Cited by 3 - Related articles - All 2 versions
A Rafacho, TM Cestari, SR Taboga, AC … - American Journal of Physiology- Endocrinology And …, 2009 - Am Physiological Soc Activation of insulin signaling and cell cycle intermediates is required for
adult β-cell proliferation. Here, we report a model to study β-cell
proliferation in living rats by administering three different doses of ... Cited by 3 - Related articles - All 3 versions
A Assmann, C Hinault, RN Kulkarni, JD … - Pediatric Diabetes, 2009 - interscience.wiley.com It is also possible that your web browser is not configured or not able to
display style sheets. In this case, although the visual presentation will be
degraded, the site should continue to be functional. We recommend using the ... Cited by 2 - Related articles - All 3 versions
MM Sachdeva, DA Stoffers - Molecular Endocrinology, 2009 - Endocrine Soc Type 2 diabetes results from pancreatic ß-cell failure in the setting of
insulin resistance. This model of disease progression has received recent
support from the results of genome-wide association studies that identify ... Cited by 2 - Related articles - All 3 versions
U IB - International Journal of Experimental Pathology - interscience.wiley.com It is well known that glucocorticoids induce peripheral insulin resistance in
rodents and humans. Here, we investigated the structural and ultrastructural
modifications, as well as the proteins involved in beta-cell function and ... Cited by 2 - Related articles - All 3 versions
D Lindberg - uu.diva-portal.org Dissertation presented at Uppsala University to be publicly examined in
Rosénsalen, Kvinnokliniken, Akademiska sjukhuset ing 95, Uppsala, Friday, March
23, 2007 at 13:00 for the degree of Doctor of Philosophy (Faculty of ... Related articles - View as HTML - All 5 versions