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Scholar Results 1 - 10 of 12 citing Vasavada: Tissue-specific deletion of the retinoblastoma protein in the pancreatic β-cell.... (0.07 sec) 

The replication of beta cells in normal physiology, in disease and for therapy.


PC Butler, JJ Meier, AE Butler, A Bhushan - Nature clinical practice. Endocrinology & metabolism, 2007 - ncbi.nlm.nih.gov
Replication of beta cells is an important source of beta-cell expansion in early
childhood. The recent linkage of type 2 diabetes with several transcription
factors involved in cell cycle regulation implies that growth of the ...
Cited by 41 - Related articles - BL Direct - All 3 versions

A gene expression network model of type 2 diabetes links cell cycle regulation in islets with …

- 171.66.122.45
MP Keller, YJ Choi, P Wang, D Belt Davis, ME … - Genome Research, 2008 - 171.66.122.45
Insulin resistance is necessary but not sufficient for the development of type 2
diabetes. Diabetes results when pancreatic beta-cells fail to compensate for
insulin resistance by increasing insulin production through an expansion of ...
Cited by 27 - Related articles - BL Direct - All 15 versions

Diabetes mellitus: an opportunity for therapy with stem cells?


V Sordi, F Bertuzzi, L Piemonti - Regen. Med., 2008 - Future Medicine
In both Type 1 and 2 diabetes, insufficient numbers of insulin-producing
β-cells are a major cause of defective control of blood glucose and its
complications. Restoration of damaged β-cells by endocrine pancreas ...
Cited by 5 - Related articles - BL Direct - All 4 versions

Differential expression of cell cycle proteins during ageing of pancreatic islet cells


C Hinault, J Hu, BF Maier, RG Mirmira, RN … - Diabetes Obes Metab, 2008 - interscience.wiley.com
One of the major challenges for developmental biologists and investigators in
the field of diabetes over the last few decades has been to dissect the origin
of pancreatic endocrine cells and to accurately understand the mechanisms ...
Cited by 3 - Related articles - All 2 versions

High doses of dexamethasone induce increased {beta}-cell proliferation in pancreatic rat …


A Rafacho, TM Cestari, SR Taboga, AC … - American Journal of Physiology- Endocrinology And …, 2009 - Am Physiological Soc
Activation of insulin signaling and cell cycle intermediates is required for
adult β-cell proliferation. Here, we report a model to study β-cell
proliferation in living rats by administering three different doses of ...
Cited by 3 - Related articles - All 3 versions

[CITATION] Growth factor control of pancreatic islet regeneration and function


A Assmann, C Hinault, RN Kulkarni, JD … - Pediatric Diabetes, 2009 - interscience.wiley.com
It is also possible that your web browser is not configured or not able to
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degraded, the site should continue to be functional. We recommend using the ...
Cited by 2 - Related articles - All 3 versions

MINIREVIEW: Meeting the demand for insulin: Molecular mechanisms of adaptive postnatal …


MM Sachdeva, DA Stoffers - Molecular Endocrinology, 2009 - Endocrine Soc
Type 2 diabetes results from pancreatic ß-cell failure in the setting of
insulin resistance. This model of disease progression has received recent
support from the results of genome-wide association studies that identify ...
Cited by 2 - Related articles - All 3 versions

Increased pancreatic islet mass is accompanied by activation of the insulin receptor …


U IB - International Journal of Experimental Pathology - interscience.wiley.com
It is well known that glucocorticoids induce peripheral insulin resistance in
rodents and humans. Here, we investigated the structural and ultrastructural
modifications, as well as the proteins involved in beta-cell function and ...
Cited by 2 - Related articles - All 3 versions

[PDF] Molecular genetic studies of sporadic and MEN1-associated endocrine pancreatic tumors


D Lindberg - uu.diva-portal.org
Dissertation presented at Uppsala University to be publicly examined in
Rosénsalen, Kvinnokliniken, Akademiska sjukhuset ing 95, Uppsala, Friday, March
23, 2007 at 13:00 for the degree of Doctor of Philosophy (Faculty of ...
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[CITATION] http://www. hh. um. es


P Yesil, E Lammert - Histol Histopathol, 2008
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