S Schenk, M Saberi, JM Olefsky - The Journal of Clinical Investigation, 2008 - pubmedcentral.nih.gov Insulin resistance is a major metabolic feature of obesity and is a key factor
in the etiology of a number of diseases, including type 2 diabetes. In this
review, we discuss potential mechanisms by which brief nutrient excess and ... Cited by 47 - Related articles - All 12 versions
- ►nih.gov D Patsouris, PP Li, D Thapar, J Chapman, JM … - Cell metabolism, 2008 - Elsevier Obese adipose tissue is characterized by infiltration of macrophages. We and
others recently showed that a specific subset of macrophages is recruited to
obese adipose and muscle tissue. This subset expresses CD11c and produces ... Cited by 17 - Related articles - All 7 versions
- ►nursing2008.com V Greenfield, O Cheung, AJ Sanyal - Current Opinion in Gastroenterology, 2008 - journals.lww.com Recent findings: Nonalcoholic fatty liver disease is present in approximately
30% of the US population. A histologic grading and staging system has been
developed and validated. Nonalcoholic fatty liver disease increases the ... Cited by 17 - Related articles - BL Direct - All 11 versions
- ►nih.gov BJ DeBosch, AJ Muslin - Journal of molecular and cellular cardiology, 2008 - Elsevier The insulin-signal transduction pathway is a highly conserved pathway that
regulates several aspects of cellular physiology, including most notably the
regulation of cellular growth and of glucose uptake and utilization. ... Cited by 4 - Related articles - All 15 versions
T Yang, ML Martin, JS Nielsen, K Milne, EM … - Cancer Immunology, Immunotherapy, 2009 - Springer Cancer Immunol Immunother (2009) 58:1867–1877 DOI 10.1007/s00262-009-0698-3 ... CD8+ T cells lacking the Cbl-b gene ... Taimei Yang · Michele L. Martin
· Julie S. Nielsen · Katy Milne · Erika M. Wall · Wendy Lin · Peter H. ... Cited by 1 - Related articles - All 2 versions
AO'Hara, FL Lim, DJ Mazzatti, P Trayhurn - Pflügers Archiv European Journal of Physiology, 2009 - Springer Abstract White adipose tissue exhibits inflammation as tissue mass expands in
obesity, involving macrophage infiltration and a direct inflammatory response by
adipo- cytes. DNA microarrays and conditioned medium have been used to ... Cited by 1 - Related articles - All 2 versions
- ►molbiolcell.org E Purev, L Neff, WC Horne, R Baron - Molecular Biology of the Cell, 2009 - Am Soc Cell Biol The domain structures of c-Cbl and Cbl-b are the most similar among the
mammalian Cbl proteins (Thien and Langdon, 2005 Go ). Like other family members,
c-Cbl and Cbl-b share a tyrosine kinase binding (TKB) domain that binds ... Related articles - All 2 versions
PJ Bilan, V Samokhvalov, A Koshkina, JD …, 2009 - Informa Pharma Science Obesity is associated with insulin resistance and increased risk for developing
type 2 diabetes. Enlarged adipocytes develop resistance to the anti-lipolytic
action of insulin. Elevated levels of fatty acids in the plasma and ... Related articles - All 5 versions
R Nakao, K Hirasaka, J Goto, K Ishidoh, C … - Molecular and Cellular Biology, 2009 - Am Soc Microbiol Skeletal muscle atrophy caused by unloading is characterized by both decreased
responsiveness to myogenic growth factors (eg, insulin-like growth factor 1
[IGF-1] and insulin) and increased proteolysis. Here, we show that ... Related articles - All 3 versions
DII Hemdan, K Hirasaka, R Nakao, S Kohno, … - The Journal of Medical Investigation, 2009 - medical.med.tokushima-u.ac.jp Unloading, as occurs in long-term bed rest, im- mobilization, and
weightlessness, causes rapid and marked muscle atrophy (1, 2). We previously re-
ported that unloading, including spaceflight as well Related articles - View as HTML - All 2 versions
